{"id":9436,"date":"2020-04-23T03:37:57","date_gmt":"2020-04-23T00:37:57","guid":{"rendered":"https:\/\/www.synevo.ro\/product\/mycoplasma-hominis-ureaplasma-urealyticum-cultura-identificare-antibiograma\/"},"modified":"2026-02-18T23:29:49","modified_gmt":"2026-02-18T21:29:49","slug":"mycoplasma-hominis-ureaplasma-urealyticum-cultura-identificare-antibiograma","status":"publish","type":"product","link":"https:\/\/old.synevo.md\/ru\/shop\/mycoplasma-hominis-ureaplasma-urealyticum-cultura-identificare-antibiograma\/","title":{"rendered":"\u041f\u043e\u0441\u0435\u0432 \u043d\u0430 \u043c\u0438\u043a\u043e\u043f\u043b\u0430\u0437\u043c\u0443 \u0445\u043e\u043c\u0438\u043d\u0438\u0441 \u0438 \u0443\u0440\u0435\u0430\u043f\u043b\u0430\u0437\u043c\u044b (Mycoplasma hominis, Ureaplasma spp.) - \u043a\u0443\u043b\u044c\u0442\u0443\u0440\u0430, \u0430\u043d\u0442\u0438\u0431\u0438\u043e\u0442\u0438\u043a\u043e\u0433\u0440\u0430\u043c\u043c\u0430"},"content":{"rendered":"

Informa\u0163<\/em><\/strong>ii generale<\/em><\/strong><\/p>\n

Mycoplasmele<\/em> sunt cunoscute ca fiind cele mai mici forme biologice ce pot supravie\u0163ui singure. Spre deosebire de toate celelalte bacterii, aceste procariote nu au perete celular. Mycoplasmele sunt ubicuitare regnului vegetal \u015fi animal, dar Mycoplasma spp<\/em>. \u015fi Ureaplasma urealyticum<\/em> colonizeaz\u0103 \u015fi infecteaz\u0103 omul \u015fi nu se g\u0103sesc la animale. Ele reprezint\u0103 cele 2 genuri ale familiei Mycoplasmataceae5<\/sup>.<\/p>\n

Mycoplasmele fac parte din flora microbian\u0103 a omului \u015fi se g\u0103sesc \u00een special la nivelul orofaringelui, tractului respirator superior \u015fi tractului urogenital. De aceea, ele sunt considerate \u00een principal microorganisme comensale.<\/p>\n

Implicarea M. genitalium<\/em>, M. pirum<\/em>, M. penetrans<\/em> \u0438 M. fermentans<\/em> \u00een bolile umane este incert\u0103; habitatul \u015fi transmisia acestor mycoplasme sunt necunoscute.<\/p>\n

Sunt cunoscute 3 specii a c\u0103ror izolare prezint\u0103 semnifica\u0163ie (M. pneumoniae<\/em>, U. urealyticum<\/em> \u0438 M. hominis<\/em>) deoarece rolul lor \u00een infec\u0163iile umane este foarte bine stabilit: U. urealyticum<\/em> \u0438 M. hominis<\/em> se pot izola din tractul genito-urinar, \u00een timp ce M. pneumoniae<\/em> se izoleaz\u0103 din tractul respirator.<\/p>\n

Mycoplasmele<\/em> \u0438 ureaplasmele<\/em> pot coloniza tractul genital al nou-n\u0103scu\u0163ilor \u00een timpul na\u015fterii. Ureaplasma<\/em> a fost izolat\u0103 la aproximativ 1\/3 din feti\u0163e, iar Mycoplasma spp.<\/em> \u00eentr-un procent mai mic, \u00een timp ce\u00a0 la b\u0103ie\u0163i aceast\u0103 colonizare este mai redus\u0103. De asemenea at\u00e2t mycoplasmele c\u00e2t \u015fi ureaplasmele au fost izolate de la nivelul nasului \u015fi faringelui la 15% dintre nou-n\u0103scu\u0163i.<\/p>\n

In general, aceast\u0103 colonizare nu persist\u0103 peste v\u00e2rsta de 2 ani, \u00eens\u0103, odat\u0103 cu pubertatea apare din nou colonizarea cu ace\u015fti germeni, ca urmare a \u00eenceperii vie\u0163ii sexuale.<\/p>\n

Colonizarea tractului genital cu Ureaplasma<\/em> este de patru ori mai frecvent\u0103 decat cea cu Mycoplasma spp.<\/em> \u015fi este mai frecvent\u0103 la femei dec\u00e2t la b\u0103rba\u0163i. Prezen\u0163a lor este dificil de interpretat, aceasta reflect\u00e2nd probabil colonizarea2<\/sup>. \u00a0<\/strong><\/p>\n

Variabilitatea antigenic\u0103, capacitatea de a suprima r\u0103spunsul imun al gazdei, rata mic\u0103 de proliferare \u015fi localizarea intracelular\u0103 ar putea explica natura cronic\u0103 a infec\u0163iilor cu Mycoplasma spp.<\/em> \u015fi incapacitatea frecvent\u0103 a gazdei de a suprima infec\u0163ia prin r\u0103spunsuri imune \u015fi non-imune3<\/sup>.<\/p>\n

Unele specii, de ex. M. pirum<\/em>, M. penetrans<\/em> \u0438 M. fermentans<\/em> au fost implicate drept cofactori infec\u0163io\u015fi \u00een infec\u0163ia cu HIV, fiind detectate \u00een aproximativ 20% din cazuri. Ele pot influen\u0163a patogeneza infec\u0163iei cu HIV prin activarea sau supresia specific\u0103 \u015fi direct\u0103 a sistemului imun, produc\u0163ia de superantigene, cu alter\u0103ri ulterioare ale r\u0103spunsurilor imune, sau prin contribu\u0163ia la stresul oxidativ. Infec\u0163ia cu HIV ar putea cre\u015fte susceptibilitatea acestor pacien\u0163i la infec\u0163ii cu diferite specii de mycoplasme, de ex. M. fermentans3<\/sup><\/em>.<\/p>\n

Aspecte clinice<\/em><\/span><\/strong><\/p>\n

Infec\u0163iile provocate de mycoplasme sunt asimptomatice \u00een 30-70% din cazuri.<\/p>\n

Mycoplasma hominis<\/em> \u0438 Ureaplasma urealyticum<\/em> sunt implicate \u00eentr-o gam\u0103 variat\u0103 de afec\u0163iuni urogenitale: boala inflamatorie pelvin\u0103, sterilitate, avort septic, uretrite nongonococice la b\u0103rba\u0163i, rar orhiepididimite, sindrom uretral la femei, infec\u0163ii puerperale acute (subacute \u015fi cronice), pielonefrite, peritonite, sindrom Reiter. Anumite serotipuri sunt implicate \u00een etiopatogenia infertilit\u0103\u0163ii4<\/sup>.<\/p>\n

Dismicrobismul vaginozelor include frecvent \u015fi M. hominis<\/em>. Tot M. hominis<\/em> poate da, rareori, vaginite prepubertare1<\/sup>.<\/p>\n

Transmiterea se poate face prin contact direct \u00eentre gazde, vertical de la mam\u0103 la f\u0103t, prin infec\u0163ii nosocomiale \u015fi prin transplant.<\/p>\n

Din totalul uretritelor nongonococice, 20-25% sunt provocate de M. hominis<\/em>, U. urealyticum<\/em> \u0438 M. genitalium<\/em>. Ace\u015fti agen\u0163i colonizeaz\u0103 vaginul femeilor care au contact cu mai mul\u0163i parteneri. Clinic se manifest\u0103 ca: vaginite, cervicite, bartholinite, febr\u0103 puerperal\u0103 \u015fi chiar sterilitate.<\/p>\n

Ureaplasma poate cauza inflama\u0163ii placentare, poate invada sacul amniotic, provoc\u00e2nd infec\u0163ii persistente \u015fi complica\u0163ii la na\u015ftere. Mycoplasma hominis<\/em> \u0438 Ureaplasma urealyticum<\/em> au fost izolate, \u00een aproximativ 10% din cazuri, din s\u00e2ngele femeilor cu febr\u0103 puerperal\u0103 sau avort, dar nu \u015fi de la femeile afebrile care au avut avorturi sau la gravidele s\u0103n\u0103toase.<\/p>\n

La persoanele cu sistem imun intact, M. hominis<\/em> \u0438 U. urealyticum<\/em> sunt, de obicei, germeni comensali ai mucoasei tractului genital inferior, prezen\u0163a lor nefiind asociat\u0103 cu manifest\u0103ri clinice. Virulen\u0163a lor este sc\u0103zut\u0103, comport\u00e2ndu-se ca oportuni\u015fti. Prezen\u0163a lor \u00een aceast\u0103 zona \u00een procente diferite este explicat\u0103 prin modul de comportament \u015fi se refer\u0103 la: statutul economic, comportamentul sexual \u015fi num\u0103rul partenerilor sexuali5<\/sup>.<\/p>\n

Infec\u0163iile cu M. hominis<\/em> \u0438 U. urealyticum<\/em>, al\u0103turi de Chlamydia trachomatis<\/em>, sunt considerate boli venerice \u201cde genera\u0163ia a III-a\u201d; infec\u0163iile evolueaz\u0103 cronic \u015fi produc o serie de complica\u0163ii, afect\u00e2nd calitatea vie\u0163ii individului. Aceste persoane pot r\u0103m\u00e2ne mult timp \u201cpurt\u0103tori s\u0103n\u0103to\u015fi\u201d ai infec\u0163iei, surse \u00een vehicularea agen\u0163ilor infec\u0163iosi pe cale sexual\u0103.<\/p>\n

In vederea reducerii morbidit\u0103\u0163ii se impun: depistarea \u015fi tratarea corect\u0103 a bolnavilor, controlul periodic al acestora pentru evitarea recidivelor \u015fi educa\u0163ia sanitar\u0103 \u00een r\u00e2ndul popula\u0163iei active sexual.<\/p>\n

Diagnosticul de laborator <\/em><\/strong><\/p>\n

Probele corespunz\u0103toare pentru cultivarea mycoplasmelor sunt: s\u00e2nge, lichid sinovial, lichid amniotic, LCR, urin\u0103, secre\u0163ie prostatic\u0103, sperm\u0103, sput\u0103, lichid pleural, lavaj bronho-alveolar etc., \u00een func\u0163ie de condi\u0163iile clinice \u015fi de suspiciunea de diagnostic.<\/p>\n

In laboratoarele Synevo se efectueaz\u0103 numai determin\u0103ri din secre\u0163ii urogenitale: \u00a0secretie vaginala si secretie col uterin pentru femei iar pentru barbati urina primul jet, secretie uretrala, secretie prostatica si sperma4<\/sup>.<\/p>\n

\u0421\u0431\u043e\u0440 \u043c\u0430\u0442\u0435\u0440\u0438\u0430\u043b\u0430<\/em><\/strong> secre\u0163iilor vaginale, col uterin \u015fi uretrale se efectueaz\u0103 cu tamponul; se va asigura rotirea viguroas\u0103 a tamponului pentru ob\u0163inerea de celule poten\u0163ial infectate cu mycoplasme. Tamponul va fi introdus \u00een recipientul furnizat de laborator.Determinarea mai poate fi efectuat\u0103 la b\u0103rba\u0163i din urina-primul jet, sperm\u0103 si secretie \u00a0prostatica.<\/p>\n

Nu se recolteaz\u0103 probe dac\u0103 s-au administrat lubrifian\u0163i sau antiseptice locale. Se recomand\u0103 tampoane de Dacron, calcium alginate sau poliester, cu m\u00e2ner de plastic sau aluminiu, deoarece\u00a0alte materiale pot avea un efect inhibitor asupra mycoplasmelor.<\/p>\n

Mycoplasmele sunt microorganisme foarte sensibile \u00een condi\u0163ii de mediu cald \u015fi uscat. De aceea, probele trebuie recoltate pe mediu de transport corespunz\u0103tor. Probele au stabilitate 24 de ore la temperatura camerei si 48 de ore la 2-8 \u00ba C.<\/p>\n

Prelucrarea probelor, valori de referin\u0163\u0103 \u015fi comunicarea rezultatelor<\/em><\/strong><\/p>\n

In laboratorul Synevo pentru cultura \u015fi identificarea Mycoplasma hominis<\/em> \u0438 Ureaplasma urealyticum<\/em> se folose\u015fte un kit ce combin\u0103 cultura \u00een bulionul selectiv cu stripul ce con\u0163ine 30 de godeuri. Bulionul furnizeaz\u0103 condi\u0163ii optime de cre\u015ftere a Mycoplasmei (pH, substraturi, asocierea mai multor factori de cre\u015ftere). Dac\u0103 o cultur\u0103 \u00een bulion este pozitiv\u0103, atunci substraturile specifice (uree pentru Ureaplasma spp<\/em> \u015fi arginina pentru M.\u00a0hominis<\/em>) \u015fi indicatorul de culoare ro\u015fu fenol prezente \u00een bulion vor conduce la schimbarea culorii, ca urmare a cre\u015fterii pH\u2013ului.<\/p>\n

Dup\u0103 inoculare, bulionul este dispersat \u00een strip, iar citirea se face la 24 ore. Acesta furnizeaza simultan rezultate<\/a><\/u> pentru identificare, apreciere semicantitativ\u0103 \u015fi testarea susceptibilit\u0103\u0163ii izolatelor fata de 13\u00a0 antibiotice din 5 clase: Tetracicline (Doxiciclina,Tetraciclina, Minociclina), Macrolide (Eritromicina, Azitromicina, Claritromicina, Roxitromicina, Josamicina), Quinolone (Ciprofloxacina, Ofloxacina, Levofloxacina), Lincosamide (Clindamicina) si Streptogramine (Pristinamicina).<\/p>\n

Trusa asigura o buna specificitate pentru produsele patologice cu contaminare microbiana (alte bacterii decat Mycoplasma si Ureaplasma).<\/p>\n

Valori de referin\u0163\u0103<\/em><\/strong><\/p>\n

Ureaplasma urealyticum \u2013 Negativ<\/div>\n
Mycoplasma hominis \u2013 Negativ<\/div>\n

In cazul unor rezultate pozitive sunt posibile dou\u0103 situa\u0163ii:<\/p>\n

    \n
  • Ureaplasma urealyticum \u015fi\/sau Mycoplasma hominis >104<\/sup> UFC\/proba; va fi comunicat\u0103 antibiograma;<\/li>\n
  • Ureaplasma urealyticum \u015fi\/sau Mycoplasma hominis <104<\/sup> UFC\/proba; va fi comunicat\u0103 antibiograma \u00eempreun\u0103 cu urm\u0103torul comentariu: \u201cAv\u00e2nd \u00een vedere c\u0103 Mycoplasama hominis \u015fi\u00a0 Ureaplasma urealyticum fac parte din flora comensal\u0103 a mucoasei tractului urogenital, medicul va interpreta oportunitatea tratamentului \u00een func\u0163ie de contextul clinic<\/em>\u201d.<\/li>\n<\/ul>\n

    Rezultatul echivoc se comunic\u0103 atunci c\u00e2nd trusa nu poate fi interpretat\u0103.<\/p>\n

    Acest aspect apare datorit\u0103 prezen\u0163ei \u00een proba a florei microbiene\u00a0(alta decat Mycoplasma<\/em> \u0438 Ureaplasma<\/em>) dotat\u0103 cu echipament enzimatic care\u00a0metabolizeaz\u0103 substraturile specifice \u015fi vireaz\u0103 indicatorul de culoare din trus\u0103. In aceast\u0103 situa\u0163ie va fi comunicat rezultatul echivoc \u00eempreun\u0103 cu urm\u0103torul comentariu: \u201cProb\u0103 contaminat\u0103 bacterian, rug\u0103m repetarea recolt\u0103rii dup\u0103 efectuarea tratamentului adecvat<\/em>\u201d4<\/sup>.<\/p>\n

    \u00a0<\/span><\/p>\n

    \u0411\u0438\u0431\u043b\u0438\u043e\u0433\u0440\u0430\u0444\u0438\u044f<\/span><\/strong><\/p>\n

    1. Daniela B\u0103descu. Identificarea Micoplasmelor \u015fi Ureaplasmelor. In Tratat de Microbiologie Clinic\u0103. Dumitru Buiuc, Marian Negu\u0163, Editura Medical\u0103, Rom\u00e2nia, Edi\u0163ia a II-a. 2008; 36:928-934.<\/span><\/span><\/div>\n
    2. J.D.C. Diaconu, O.A. Coman, V. Benea. Tratat de terapeutic\u0103 dermato \u2013 venerologic\u0103. In Via\u0163a Medical\u0103 Romaneasc\u0103, Rom\u00e2nia Ed. 2002, 790-793.<\/span><\/div>\n
    3. Ken B.Waites, David Taylor-Robinson. Mycoplasma and Ureaplasma. In Manual of Clinical Microbiology. Patrick R. Murray et al, ASM PRESS, USA,9-Th Edition. 2007;64:1004-1020.<\/span><\/div>\n
    4. Laborator Synevo. Referin\u0163ele specifice tehnologiei de lucru utilizate 2010. Ref Type: Catalog<\/span><\/div>\n
    5. Olga-Mihaela Dorobat. Familia Mycoplasmataceae. In Bacteriologie Medical\u0103. Universitatea \u201cTitu Maiorescu\u201d, Rom\u00e2nia Ed. 2006;32:429-435.<\/span><\/div>","protected":false},"excerpt":{"rendered":"

    \u041c\u0438\u043a\u043e\u043f\u043b\u0430\u0437\u043c\u044b \u0438 \u0443\u0440\u0435\u0430\u043f\u043b\u0430\u0437\u043c\u044b \u2212 \u0433\u0440\u0443\u043f\u043f\u0430 \u0433\u0440\u0430\u043c\u043e\u0442\u0440\u0438\u0446\u0430\u0442\u0435\u043b\u044c\u043d\u044b\u0445 \u0431\u0430\u043a\u0442\u0435\u0440\u0438\u0439 \u0440\u0430\u0437\u043c\u0435\u0440\u043e\u043c 115-200 \u043d\u043c. \u041f\u043e\u043a\u0440\u044b\u0442\u044b \u0442\u0440\u0435\u0445\u0441\u043b\u043e\u0439\u043d\u043e\u0439 \u043c\u0435\u043c\u0431\u0440\u0430\u043d\u043e\u0439, \u043d\u0435 \u0438\u043c\u0435\u044e\u0442 \u043f\u043b\u043e\u0442\u043d\u043e\u0439 \u043a\u043b\u0435\u0442\u043e\u0447\u043d\u043e\u0439 \u0441\u0442\u0435\u043d\u043a\u0438 (\u043f\u043e\u044d\u0442\u043e\u043c\u0443 \u0434\u0430\u043d\u043d\u044b\u0435 \u043c\u0438\u043a\u0440\u043e\u043e\u0440\u0433\u0430\u043d\u0438\u0437\u043c\u044b \u0443\u0441\u0442\u043e\u0439\u0447\u0438\u0432\u044b \u043a \u043f\u0435\u043d\u0438\u0446\u0438\u043b\u043b\u0438\u043d\u0443 \u0438 \u0434\u0440\u0443\u0433\u0438\u043c \u0430\u043d\u0442\u0438\u0431\u0438\u043e\u0442\u0438\u043a\u0430\u043c, \u0431\u043b\u043e\u043a\u0438\u0440\u0443\u044e\u0449\u0438\u043c \u0441\u0438\u043d\u0442\u0435\u0437 \u043a\u043b\u0435\u0442\u043e\u0447\u043d\u043e\u0439 \u0441\u0442\u0435\u043d\u043a\u0438). \u0412 \u0441\u043e\u043e\u0442\u0432\u0435\u0442\u0441\u0442\u0432\u0438\u0438 \u0441 \u0441\u043e\u0432\u0440\u0435\u043c\u0435\u043d\u043d\u043e\u0439 \u043a\u043b\u0430\u0441\u0441\u0438\u0444\u0438\u043a\u0430\u0446\u0438\u0435\u0439 \u043c\u0438\u043a\u043e\u043f\u043b\u0430\u0437\u043c\u044b \u043e\u0442\u043d\u0435\u0441\u0435\u043d\u044b \u043a \u0440\u043e\u0434\u0443 \u043c\u043e\u043b\u043b\u0438\u043a\u0443\u0442\u044b (Mollicutes), \u043f\u043e\u0440\u044f\u0434\u043a\u0443 \u043c\u0438\u043a\u043e\u043f\u043b\u0430\u0437\u043c\u044b (Mycoplasmatacea), \u0432\u043a\u043b\u044e\u0447\u0430\u044e\u0449\u0435\u043c\u0443 \u0432 \u0441\u0435\u0431\u044f \u0434\u0432\u0430 \u0440\u043e\u0434\u0430: \u043c\u0438\u043a\u043e\u043f\u043b\u0430\u0437\u043c\u0430 (Mycoplasma) \u2212 \u0431\u043e\u043b\u0435\u0435 \u0441\u0442\u0430 \u0432\u0438\u0434\u043e\u0432 \u0438 \u0443\u0440\u0435\u043f\u043b\u0430\u0437\u043c\u0430 (Ureaplasma) \u2212 \u0442\u0440\u0438 \u0432\u0438\u0434\u0430 \u0438 \u0448\u0435\u0441\u0442\u043d\u0430\u0434\u0446\u0430\u0442\u044c \u0441\u0435\u0440\u043e\u0442\u0438\u043f\u043e\u0432.<\/p>\n

    \u0412 \u043d\u0430\u0441\u0442\u043e\u044f\u0449\u0435\u0435 \u0432\u0440\u0435\u043c\u044f Mycoplasma hominis \u0438 Ureaplasma spp. \u0441\u0447\u0438\u0442\u0430\u044e\u0442\u0441\u044f \u0443\u0441\u043b\u043e\u0432\u043d\u043e-\u043f\u0430\u0442\u043e\u0433\u0435\u043d\u043d\u044b\u043c\u0438 \u043c\u0438\u043a\u0440\u043e\u043e\u0440\u0433\u0430\u043d\u0438\u0437\u043c\u0430\u043c\u0438, \u043a\u043e\u0442\u043e\u0440\u044b\u0435 \u0432\u044b\u0437\u044b\u0432\u0430\u044e\u0442 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u044f \u043e\u0440\u0433\u0430\u043d\u043e\u0432 \u0443\u0440\u043e\u0433\u0435\u043d\u0438\u0442\u0430\u043b\u044c\u043d\u043e\u0433\u043e \u0442\u0440\u0430\u043a\u0442\u0430 \u0443 \u043c\u0443\u0436\u0447\u0438\u043d \u0438 \u0436\u0435\u043d\u0449\u0438\u043d.<\/p>\n

    \u041c\u0438\u043a\u043e\u043f\u043b\u0430\u0437\u043c\u0435\u043d\u043d\u0430\u044f \u0438 \u0443\u0440\u0435\u0430\u043f\u043b\u0430\u0437\u043c\u0435\u043d\u043d\u0430\u044f \u0438\u043d\u0444\u0435\u043a\u0446\u0438\u044f \u043e\u0431\u043b\u0430\u0434\u0430\u0435\u0442 \u0448\u0438\u0440\u043e\u043a\u0438\u043c \u0441\u043f\u0435\u043a\u0442\u0440\u043e\u043c \u043a\u043b\u0438\u043d\u0438\u0447\u0435\u0441\u043a\u0438\u0445 \u043f\u0440\u043e\u044f\u0432\u043b\u0435\u043d\u0438\u0439: \u0431\u0435\u0441\u0441\u0438\u043c\u043f\u0442\u043e\u043c\u043d\u044b\u0445, \u043b\u0430\u0442\u0435\u043d\u0442\u043d\u043e \u043f\u0440\u043e\u0442\u0435\u043a\u0430\u044e\u0449\u0438\u0445, \u0442\u044f\u0436\u0435\u043b\u044b\u0445 \u043c\u0430\u043d\u0438\u0444\u0435\u0441\u0442\u043d\u044b\u0445 \u0444\u043e\u0440\u043c.<\/p>\n

    \u041c\u0438\u043a\u043e\u043f\u043b\u0430\u0437\u043c\u044b \u043c\u043e\u0436\u043d\u043e \u043e\u0431\u043d\u0430\u0440\u0443\u0436\u0438\u0442\u044c, \u043f\u043e \u0434\u0430\u043d\u043d\u044b\u043c \u0440\u0430\u0437\u043d\u044b\u0445 \u0438\u0441\u0442\u043e\u0447\u043d\u0438\u043a\u043e\u0432, \u0443 10-50% \u0437\u0434\u043e\u0440\u043e\u0432\u044b\u0445 \u0436\u0435\u043d\u0449\u0438\u043d (\u0447\u0430\u0441\u0442\u043e\u0442\u0430 \u0432\u044b\u044f\u0432\u043b\u0435\u043d\u0438\u044f \u0443\u0432\u0435\u043b\u0438\u0447\u0438\u0432\u0430\u0435\u0442\u0441\u044f \u0432\u043e \u0432\u0440\u0435\u043c\u044f \u0431\u0435\u0440\u0435\u043c\u0435\u043d\u043d\u043e\u0441\u0442\u0438) \u0438 8-9% \u0437\u0434\u043e\u0440\u043e\u0432\u044b\u0445 \u043c\u0443\u0436\u0447\u0438\u043d. \u0418\u0441\u0442\u043e\u0447\u043d\u0438\u043a \u0438\u043d\u0444\u0435\u043a\u0446\u0438\u0438 M. hominis \u2212 \u0447\u0435\u043b\u043e\u0432\u0435\u043a, \u0431\u043e\u043b\u044c\u043d\u043e\u0439 \u043c\u0438\u043a\u043e\u043f\u043b\u0430\u0437\u043c\u043e\u0437\u043e\u043c, \u0438\u043b\u0438 \u0437\u0434\u043e\u0440\u043e\u0432\u044b\u0439 \u043d\u043e\u0441\u0438\u0442\u0435\u043b\u044c \u043c\u0438\u043a\u043e\u043f\u043b\u0430\u0437\u043c. \u0417\u0430\u0440\u0430\u0436\u0435\u043d\u0438\u0435 \u043f\u0440\u043e\u0438\u0441\u0445\u043e\u0434\u0438\u0442 \u043f\u0440\u0435\u0438\u043c\u0443\u0449\u0435\u0441\u0442\u0432\u0435\u043d\u043d\u043e \u043f\u043e\u043b\u043e\u0432\u044b\u043c \u043f\u0443\u0442\u0435\u043c, \u0432\u043e\u0437\u043c\u043e\u0436\u0435\u043d \u0438 \u043d\u0435\u043f\u0440\u044f\u043c\u043e\u0439 \u043f\u0443\u0442\u044c \u0437\u0430\u0440\u0430\u0436\u0435\u043d\u0438\u044f \u0436\u0435\u043d\u0449\u0438\u043d, \u043e\u0441\u043e\u0431\u0435\u043d\u043d\u043e \u0434\u0435\u0432\u043e\u0447\u0435\u043a, \u0447\u0435\u0440\u0435\u0437 \u043f\u0440\u0435\u0434\u043c\u0435\u0442\u044b \u043e\u0431\u0438\u0445\u043e\u0434\u0430.<\/p>\n

    Mycoplasma hominis \u0432\u044b\u0437\u044b\u0432\u0430\u0435\u0442 \u043f\u043e\u0440\u0430\u0436\u0435\u043d\u0438\u0435 \u0443\u0440\u043e\u0433\u0435\u043d\u0438\u0442\u0430\u043b\u044c\u043d\u043e\u0433\u043e \u0442\u0440\u0430\u043a\u0442\u0430, \u0447\u0430\u0441\u0442\u043e \u0441\u043e\u0447\u0435\u0442\u0430\u0435\u0442\u0441\u044f \u0441 \u0433\u043e\u043d\u043e\u043a\u043e\u043a\u043a\u0430\u043c\u0438, \u0442\u0440\u0438\u0445\u043e\u043c\u043e\u043d\u0430\u0434\u0430\u043c\u0438, \u0430 \u0442\u0430\u043a\u0436\u0435 \u0441 \u0434\u0440\u0443\u0433\u0438\u043c\u0438 \u0443\u0441\u043b\u043e\u0432\u043d\u043e-\u043f\u0430\u0442\u043e\u0433\u0435\u043d\u043d\u044b\u043c\u0438 \u043c\u0438\u043a\u0440\u043e\u043e\u0440\u0433\u0430\u043d\u0438\u0437\u043c\u0430\u043c\u0438. \u041c\u043e\u0436\u0435\u0442 \u0431\u044b\u0442\u044c \u043f\u0440\u0438\u0447\u0438\u043d\u043e\u0439 \u043d\u0435\u0433\u043e\u043d\u043e\u043a\u043e\u043a\u043a\u043e\u0432\u043e\u0433\u043e \u0443\u0440\u0435\u0442\u0440\u0438\u0442\u0430, \u043f\u0440\u043e\u0441\u0442\u0430\u0442\u0438\u0442\u0430, \u0432\u043e\u0441\u043f\u0430\u043b\u0438\u0442\u0435\u043b\u044c\u043d\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439 \u043e\u0440\u0433\u0430\u043d\u043e\u0432 \u043c\u0430\u043b\u043e\u0433\u043e \u0442\u0430\u0437\u0430, \u043f\u0430\u0442\u043e\u043b\u043e\u0433\u0438\u0438 \u0431\u0435\u0440\u0435\u043c\u0435\u043d\u043d\u043e\u0441\u0442\u0438 \u0438 \u043f\u043b\u043e\u0434\u0430, \u0431\u0435\u0441\u043f\u043b\u043e\u0434\u0438\u044f \u0443 \u0436\u0435\u043d\u0449\u0438\u043d \u0438 \u043c\u0443\u0436\u0447\u0438\u043d.<\/p>\n

    \u041f\u043e\u043a\u0430\u0437\u0430\u0442\u0435\u043b\u044c \u0438\u043d\u0444\u0438\u0446\u0438\u0440\u043e\u0432\u0430\u043d\u0438\u044f Ureaplasma urealyticum (U. urealyticum) \u0443 \u0440\u0430\u0437\u043b\u0438\u0447\u043d\u044b\u0445 \u0433\u0440\u0443\u043f\u043f \u043d\u0430\u0441\u0435\u043b\u0435\u043d\u0438\u044f \u0432\u0435\u043b\u0438\u043a \u0438 \u043d\u0435 \u0432\u0441\u0435\u0433\u0434\u0430 \u0441\u0432\u044f\u0437\u0430\u043d \u0441 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u044f\u043c\u0438 \u043c\u043e\u0447\u0435\u043f\u043e\u043b\u043e\u0432\u044b\u0445 \u043e\u0440\u0433\u0430\u043d\u043e\u0432. \u0423\u0440\u0435\u0430\u043f\u043b\u0430\u0437\u043c\u043e\u0437 \u043d\u0435 \u0432\u0445\u043e\u0434\u0438\u0442 \u0432 \u043f\u0435\u0440\u0435\u0447\u0435\u043d\u044c \u0418\u041f\u041f\u041f (\u041c\u041a\u0411-10), \u0445\u043e\u0442\u044f \u0447\u0430\u0441\u0442\u043e \u0441\u043e\u0447\u0435\u0442\u0430\u0435\u0442\u0441\u044f \u0441 \u0433\u043e\u043d\u043e\u043a\u043e\u043a\u043a\u0430\u043c\u0438, \u0442\u0440\u0438\u0445\u043e\u043c\u043e\u043d\u0430\u0434\u0430\u043c\u0438 \u0438 \u0443\u0441\u043b\u043e\u0432\u043d\u043e-\u043f\u0430\u0442\u043e\u0433\u0435\u043d\u043d\u044b\u043c\u0438 \u043c\u0438\u043a\u0440\u043e\u043e\u0440\u0433\u0430\u043d\u0438\u0437\u043c\u0430\u043c\u0438, \u043a\u043e\u0442\u043e\u0440\u044b\u0435 \u043f\u0435\u0440\u0435\u0434\u0430\u044e\u0442\u0441\u044f \u043f\u0440\u0438 \u043f\u043e\u043b\u043e\u0432\u044b\u0445 \u043a\u043e\u043d\u0442\u0430\u043a\u0442\u0430\u0445 \u0438 \u043c\u043e\u0433\u0443\u0442 \u0441\u0442\u0430\u0442\u044c \u043f\u0440\u0438\u0447\u0438\u043d\u043e\u0439 \u043d\u0435\u0433\u043e\u043d\u043e\u043a\u043e\u043a\u043a\u043e\u0432\u043e\u0433\u043e \u0443\u0440\u0435\u0442\u0440\u0438\u0442\u0430 \u0438 \u043f\u0440\u043e\u0441\u0442\u0430\u0442\u0438\u0442\u0430 \u0443 \u043c\u0443\u0436\u0447\u0438\u043d, \u0432\u043e\u0441\u043f\u0430\u043b\u0438\u0442\u0435\u043b\u044c\u043d\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439 \u043e\u0440\u0433\u0430\u043d\u043e\u0432 \u043c\u0430\u043b\u043e\u0433\u043e \u0442\u0430\u0437\u0430, \u043f\u0430\u0442\u043e\u043b\u043e\u0433\u0438\u0438 \u0431\u0435\u0440\u0435\u043c\u0435\u043d\u043d\u043e\u0441\u0442\u0438 \u0438 \u043f\u043b\u043e\u0434\u0430, \u0431\u0435\u0441\u043f\u043b\u043e\u0434\u0438\u044f \u0443 \u0436\u0435\u043d\u0449\u0438\u043d \u0438 \u043c\u0443\u0436\u0447\u0438\u043d.<\/p>\n

    \u0414\u043b\u044f \u0432\u044b\u044f\u0432\u043b\u0435\u043d\u0438\u044f \u0432\u043e\u0437\u0431\u0443\u0434\u0438\u0442\u0435\u043b\u044f \u0438\u0441\u043f\u043e\u043b\u044c\u0437\u0443\u044e\u0442 \u043c\u0435\u0442\u043e\u0434 \u0431\u0430\u043a\u0442\u0435\u0440\u0438\u0430\u043b\u044c\u043d\u043e\u0433\u043e \u043f\u043e\u0441\u0435\u0432\u0430. \u041f\u0440\u0438 \u044d\u0442\u043e\u043c \u0434\u043e 80% \u0441\u043b\u0443\u0447\u0430\u0435\u0432 \u0432\u044b\u044f\u0432\u043b\u044f\u0435\u0442\u0441\u044f \u0441\u043e\u0432\u043c\u0435\u0441\u0442\u043d\u043e\u0435 \u0438\u043d\u0444\u0438\u0446\u0438\u0440\u043e\u0432\u0430\u043d\u0438\u0435 \u043c\u0438\u043a\u043e\u043f\u043b\u0430\u0437\u043c\u043e\u0439 \u0438 \u043f\u0440\u0435\u0434\u0441\u0442\u0430\u0432\u0438\u0442\u0435\u043b\u044f\u043c\u0438 \u0430\u043d\u0430\u044d\u0440\u043e\u0431\u043d\u043e\u0439 \u043c\u0438\u043a\u0440\u043e\u0444\u043b\u043e\u0440\u044b.<\/p>\n

    \u0412\u044b\u0434\u0435\u043b\u044f\u0435\u043c\u044b\u0435 \u0432\u043e\u0437\u0431\u0443\u0434\u0438\u0442\u0435\u043b\u0438: Mycoplasma hominis, Ureaplasma spp.<\/p>\n

    \u041c\u0430\u0442\u0435\u0440\u0438\u0430\u043b \u0434\u043b\u044f \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u044f<\/p>\n

    \u0412 \u0437\u0430\u0432\u0438\u0441\u0438\u043c\u043e\u0441\u0442\u0438 \u043e\u0442 \u043f\u043e\u043a\u0430\u0437\u0430\u043d\u0438\u0439:<\/p>\n

      \n
    • \u0443 \u0436\u0435\u043d\u0449\u0438\u043d \u043f\u043e\u0434\u043b\u0435\u0436\u0430\u0442 \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u044e \u043c\u0430\u0437\u043a\u0438 \u0438\u0437 \u0443\u0440\u0435\u0442\u0440\u044b, \u0432\u0430\u0433\u0438\u043d\u044b, \u0448\u0435\u0439\u043a\u0438 \u043c\u0430\u0442\u043a\u0438<\/li>\n
    • \u0443 \u043c\u0443\u0436\u0447\u0438\u043d \u2013 \u043c\u0430\u0437\u043e\u043a \u0438\u0437 \u0443\u0440\u0435\u0442\u0440\u044b, \u0441\u0435\u043a\u0440\u0435\u0442 \u043f\u0440\u043e\u0441\u0442\u0430\u0442\u044b, \u044d\u044f\u043a\u0443\u043b\u044f\u0442<\/li>\n<\/ul>\n

      \u0418\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u0435 \u043f\u0440\u043e\u0432\u043e\u0434\u044f\u0442 \u0441 \u0446\u0435\u043b\u044c\u044e \u0432\u044b\u0434\u0435\u043b\u0435\u043d\u0438\u044f, \u0438\u0434\u0435\u043d\u0442\u0438\u0444\u0438\u043a\u0430\u0446\u0438\u0438 \u0432\u043e\u0437\u0431\u0443\u0434\u0438\u0442\u0435\u043b\u0435\u0439 \u043c\u0438\u043a\u043e\u043f\u043b\u0430\u0437\u043c\u043e\u0437\u0430 \u0438 \u043e\u043f\u0440\u0435\u0434\u0435\u043b\u0435\u043d\u0438\u044f \u0438\u0445 \u0447\u0443\u0432\u0441\u0442\u0432\u0438\u0442\u0435\u043b\u044c\u043d\u043e\u0441\u0442\u0438 \u043a \u0430\u043d\u0442\u0438\u0431\u0438\u043e\u0442\u0438\u043a\u0430\u043c.<\/p>\n

      \u0418\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u0435 \u043f\u0440\u043e\u0432\u043e\u0434\u044f\u0442 \u0441 \u0446\u0435\u043b\u044c\u044e \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0438 \u0443\u0440\u043e\u0433\u0435\u043d\u0438\u0442\u0430\u043b\u044c\u043d\u043e\u0439 \u0438\u043d\u0444\u0435\u043a\u0446\u0438\u0438, \u0432\u044b\u0437\u0432\u0430\u043d\u043d\u043e\u0439 Ureaplasma spp., \u0432\u044b\u0431\u043e\u0440\u0430 \u0430\u043d\u0442\u0438\u0431\u0438\u043e\u0442\u0438\u043a\u043e\u0432 \u0438 \u043a\u043e\u043d\u0442\u0440\u043e\u043b\u044f \u0430\u043d\u0442\u0438\u0431\u0430\u043a\u0442\u0435\u0440\u0438\u0430\u043b\u044c\u043d\u043e\u0439 \u0442\u0435\u0440\u0430\u043f\u0438\u0438.<\/p>\n

      \u0427\u0442\u043e \u043c\u043e\u0436\u0435\u0442 \u043f\u043e\u0432\u043b\u0438\u044f\u0442\u044c \u043d\u0430 \u0440\u0435\u0437\u0443\u043b\u044c\u0442\u0430\u0442 \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u044f – \u041d\u0430\u0440\u0443\u0448\u0435\u043d\u0438\u0435 \u043f\u0440\u0430\u0432\u0438\u043b \u043f\u043e\u0434\u0433\u043e\u0442\u043e\u0432\u043a\u0438 \u043a \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u044e \u043c\u043e\u0436\u0435\u0442 \u043f\u043e\u0432\u043b\u0438\u044f\u0442\u044c \u043d\u0430 \u0440\u0435\u0437\u0443\u043b\u044c\u0442\u0430\u0442.<\/p>\n

      \u041f\u0440\u0430\u0432\u0438\u043b\u0430 \u043f\u043e\u0434\u0433\u043e\u0442\u043e\u0432\u043a\u0438 \u043a \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u044e – \u0418\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u0435 \u043f\u0440\u043e\u0432\u043e\u0434\u044f\u0442 \u0434\u043e \u043d\u0430\u0447\u0430\u043b\u0430 \u043f\u0440\u0438\u0435\u043c\u0430 \u0430\u043d\u0442\u0438\u0431\u0438\u043e\u0442\u0438\u043a\u043e\u0432. \u0415\u0441\u043b\u0438 \u0434\u043b\u044f \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u044f \u0431\u0435\u0440\u0443\u0442 \u043c\u0430\u0437\u043e\u043a \u0438\u0437 \u0443\u0440\u0435\u0442\u0440\u044b, \u0441\u0431\u043e\u0440 \u043c\u0430\u0442\u0435\u0440\u0438\u0430\u043b\u0430 \u043f\u0440\u043e\u0432\u043e\u0434\u044f\u0442 \u0434\u043e \u0438\u043b\u0438 \u043d\u0435 \u0440\u0430\u043d\u0435\u0435 2-3 \u0447\u0430\u0441\u043e\u0432 \u043f\u043e\u0441\u043b\u0435 \u043c\u043e\u0447\u0435\u0438\u0441\u043f\u0443\u0441\u043a\u0430\u043d\u0438\u044f.<\/p>\n

      \u0423 \u0436\u0435\u043d\u0449\u0438\u043d \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u0435 \u043d\u0435 \u043f\u0440\u043e\u0432\u043e\u0434\u0438\u0442\u0441\u044f \u0432\u043e \u0432\u0440\u0435\u043c\u044f \u043c\u0435\u043d\u0441\u0442\u0440\u0443\u0430\u0446\u0438\u0438, \u043c\u0430\u0442\u0435\u0440\u0438\u0430\u043b \u0441\u043b\u0435\u0434\u0443\u0435\u0442 \u0431\u0440\u0430\u0442\u044c \u043d\u0435 \u0440\u0430\u043d\u0435\u0435 5-7 \u0434\u043d\u044f \u043c\u0435\u0441\u044f\u0447\u043d\u043e\u0433\u043e \u0446\u0438\u043a\u043b\u0430 \u0438 \u0434\u043e \u0435\u0433\u043e \u043e\u043a\u043e\u043d\u0447\u0430\u043d\u0438\u044f.<\/p>","protected":false},"featured_media":0,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[974,979],"product_tag":[],"class_list":{"0":"post-9436","1":"product","2":"type-product","3":"status-publish","5":"product_cat-teste-de-microbiologie","6":"product_cat-tract-urogenital","8":"first","9":"instock","10":"sold-individually","11":"shipping-taxable","12":"purchasable","13":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/product\/9436","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/comments?post=9436"}],"wp:attachment":[{"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/media?parent=9436"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/product_brand?post=9436"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/product_cat?post=9436"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/product_tag?post=9436"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}