{"id":9326,"date":"2020-04-23T04:34:48","date_gmt":"2020-04-23T01:34:48","guid":{"rendered":"https:\/\/www.synevo.ro\/product\/uree-serica\/"},"modified":"2026-02-19T01:28:32","modified_gmt":"2026-02-18T23:28:32","slug":"uree-serica","status":"publish","type":"product","link":"https:\/\/old.synevo.md\/ru\/shop\/uree-serica\/","title":{"rendered":"\u041c\u043e\u0447\u0435\u0432\u0438\u043d\u0430 \u0432 \u043a\u0440\u043e\u0432\u0438"},"content":{"rendered":"

\u041e\u0431\u0449\u0430\u044f \u0438\u043d\u0444\u043e\u0440\u043c\u0430\u0446\u0438\u044f<\/em><\/strong><\/p>\n

Ureea este principalul produs azotat final al metabolismului aminoacizilor, proveniti din scindarea in stomac si intestin a proteinelor, sub actiunea fermentilor proteolitici si absorbtia acestora prin peretele intestinal. Sediul principal de formare a ureei este ficatul, dar si tesutul in curs de crestere (de exemplu, tesutul embrionar sau tumoral) are proprietatea de a forma uree din arginina. Cea mai mare parte a ureei este eliminata prin filtrare glomerulara; 40-60% redifuzeaza in sange in functie de fluxul tubular si de hormonul antidiuretic (ADH)6<\/sup>.<\/p>\n

Ureea din sange si urina variaza in raport direct proportional cu alimentatia proteica si invers proportional cu anabolismul celular din cursul starilor de crestere, graviditate, convalescenta3<\/sup>. De asemenea, concentratia plasmatica a ureei depinde de perfuzia renala: in prezenta diurezei redifuzia ureei in sange din tubii renali distali este minima, o cantitate mare de uree este excretata in urina si nivelul ureei serice ramane scazut; daca este prezenta antidiureza, ca in sete, exsicoza, insuficienta cardiaca oligurica, ureea redifuzeaza din tubii distali in sange, iar nivelurile plasmatice ale ureei cresc. Niveluri persistent crescute ale ureei serice indica alterarea semnificativa a ratei filtrarii glomerulare. La un aport proteic normal de 100 g\/zi si perfuzie renala normala, niveluri crescute ale ureei serice nu se intalnesc pana cand rata filtrarii glomerulare nu scade la 30 mL\/min6<\/sup>.<\/p>\n

In laborator se determina atat ureea serica propriu-zisa cat si portiunea azotata a ureei: ureea nitrogen (BUN).<\/p>\n

Recomandari pentru determinarea ureei serice <\/em><\/strong>\u2013 diagnosticul insuficientei renale; diferentierea intre azotemia prerenala si postrenala pe baza raportului uree\/creatinina; in insuficienta renala terminala, intrucat semnele urotoxice se coreleaza bine cu nivelul ureei; monitorizarea succesului dietei hipoproteice in insuficienta renala cronica; monitorizarea hemodializei5<\/sup>;6<\/sup>.<\/p>\n

Pregatire pacient <\/em><\/strong>-\u00a0 <\/em><\/strong>\u00e0 jeun (pe nemancate) sau postprandial4<\/sup>.<\/p>\n

Specimen recoltat <\/em><\/strong>-sange venos4<\/sup>.<\/p>\n

Recipient de recolta <\/em><\/strong>\u2013 vacutainer fara anticoagulant cu\/fara gel separator4<\/sup>.<\/p>\n

Prelucrare necesara dupa recoltare <\/em><\/strong>\u2013 se separa serul prin centrifugare4<\/sup>.<\/p>\n

Volum proba<\/em><\/strong> \u2013 minim 0.5 mL ser4<\/sup>.<\/p>\n

Stabilitate proba <\/em><\/strong>\u2013 serul separat este stabil 7 zile<\/em> la temperatura camerei; 7 zile<\/em> la 2-8\u00b0C; 1 an<\/em> la -20\u00b0C4<\/sup>.<\/p>\n

Metoda <\/em><\/strong>- spectrofotometrica (kinetica)<\/span>4<\/sup>.<\/p>\n

Valori de referinta <\/em><\/strong>\u2013 sunt dependente de varsta4<\/sup>.<\/p>\n

\u2022 uree<\/em><\/strong>:<\/p>\n\n\n\n\n\n\n\n
\n

Varsta<\/em><\/strong><\/p>\n<\/td>\n

\n

Valoare <\/em><\/strong>(<\/em><\/strong>mg\/dL)<\/em><\/strong><\/p>\n<\/td>\n<\/tr>\n

\n

< 1 an<\/p>\n<\/td>\n

\n

<41<\/p>\n<\/td>\n<\/tr>\n

\n

1-18 ani<\/p>\n<\/td>\n

\n

<39<\/p>\n<\/td>\n<\/tr>\n

\n

18-60 ani<\/p>\n<\/td>\n

\n

<43<\/p>\n<\/td>\n<\/tr>\n

\n

60-90\u00a0ani<\/p>\n<\/td>\n

\n

<49<\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\u2022 uree nitrogen (BUN<\/em><\/strong>):<\/p>\n\n\n\n\n\n\n\n
\n

Varsta<\/em><\/strong><\/p>\n<\/td>\n

\n

Valoare <\/em><\/strong>(<\/em><\/strong>mg\/dL)<\/em><\/strong><\/p>\n<\/td>\n<\/tr>\n

\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 < 1 an<\/td>\n\n

<19<\/p>\n<\/td>\n<\/tr>\n

\n

1-18 ani<\/p>\n<\/td>\n

\n

<18<\/p>\n<\/td>\n<\/tr>\n

\n

18-60 ani<\/p>\n<\/td>\n

\n

<20<\/p>\n<\/td>\n<\/tr>\n

\n

60-90\u00a0ani<\/p>\n<\/td>\n

\n

<23<\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Factor de conversie: mg\/dL x 0.166 = mmol\/L;\u00a0 mmol\/L x 6.024 = mg\/dL; mg\/dL uree nitrogen x 0.357 = mmol\/L uree; mg\/dL uree nitrogen x 2.14 = mg\/dL uree;\u00a0 mg\/dL uree x 0.467 = mg\/dL uree nitrogen<\/em>.<\/p>\n

Limita de detectie<\/em><\/strong> \u2013 0.5 mmol\/L (3 mg\/dL)4<\/sup><\/p>\n

Valori critice <\/em><\/strong>- >100 mg\/dL<\/strong>1<\/sup>.<\/span><\/p>\n

Interpretarea rezultatelor<\/em><\/strong><\/p>\n

\u2022\u00a0 o valoare scazuta a ureei, de 6-8 mg\/dL, se asociaza frecvent cu o stare de hiperhidratare;<\/p>\n

\u2022\u00a0 o valoare de 10-20 mg\/dL indica o functie glomerulara normala;<\/p>\n

\u2022\u00a0 cresterea ureei sanguine la 50-150 mg\/dL presupune o afectare semnificativa a functiei renale;<\/p>\n

\u2022\u00a0 o valoare marcat crescuta a ureei, de 150-250 mg\/dL, indica o afectare severa a functiei glomerulare.<\/p>\n

In insuficienta renala cronica valorile ureei sanguine se coreleaza mai bine cu simptomele de uremie decat cele ale creatininei serice3<\/sup>.<\/p>\n\n\n\n\n
\n

Cresteri<\/em><\/strong><\/p>\n<\/td>\n

\n

Scaderi<\/em><\/strong><\/p>\n<\/td>\n<\/tr>\n

\n

Starile asociate cu cresterea ureei serice sunt cunoscute ca azotemie:<\/p>\n

\u2022 scaderea perfuziei renale (azotemie prerenala<\/span>): insuficienta cardiaca congestiva, hemoragie digestiva, soc, deshidratare;<\/p>\n

\u2022 afectiuni renale, acute sau cronice (azotemie renala<\/span>): glomerulonefrite, pielonefrite;<\/p>\n

\u2022 obstructii ale tractului urinar (azotemie postrenala<\/span>);<\/p>\n

\u2022 intensificarea catabolismului proteic (valorile creatininei serice raman neschimbate): arsuri, neoplazii, stari febrile prelungite, stres, IMA etc.;<\/p>\n

\u2022 diabet zaharat cu cetoacidoza1;3<\/sup>;6<\/sup>.<\/p>\n<\/td>\n

\n

\u2022 afectiuni hepatice severe (insuficienta hepatica): toxice, infectioase; \u2022acromegalie;<\/p>\n

\u2022 malnutritie; \u2022 malabsorbtie;<\/p>\n

\u2022 hormoni anabolizanti;<\/p>\n

\u2022 SIADH (sindromul secretiei inadecvate de ADH-hormon antidiuretic)1<\/sup>;<\/p>\n

\u2022 hiperamoniemiile ereditare (ureea este virtual absenta in sange)3<\/sup>;6<\/sup>.<\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Limite si interferente<\/em><\/strong><\/p>\n

\u2022 Variatii fiziologice<\/p>\n

In mod normal copiii prezinta valori mai scazute ale ureei serice (catabolism proteic scazut legat de crestere)6<\/sup>.<\/p>\n

In ultima parte a sarcinii pot aparea valori scazute ale ureei serice datorita hipervolemiei fiziologice.<\/p>\n

\u2022 Factori legati de dieta<\/p>\n

O dieta hipoproteica, dar cu un continut crescut de carbohidrati, poate cauza scaderi ale ureei serice1<\/sup>.<\/p>\n

Ingestia recenta a unei mese bogate in proteine poate determina valori \u201cborderline\u201d crescute ale ureei serice5<\/sup>. Aportul crescut de proteine (>200 g\/zi), in special daca se asociaza cu aport redus de lichide, transpiratii profuze sau poliurie indusa de alcool, poate duce la cresterea nivelului seric al ureei pana la 80 mg\/dL6<\/sup>.<\/p>\n

\u2022 Conditii patologice: administrarea intravenoasa excesiva de fluide poate determina scaderea ureei serice5<\/sup>.<\/p>\n

Ureea serica nu este un parametru specific, nici sensibil pentru stabilirea debutului unei disfunctii glomerulare. In prezenta unei disfunctii renale mai pronuntate concentratia ureei serice se coreleaza mai bine cu rata filtrarii glomerulare6<\/sup>.<\/p>\n

In insuficienta renala cronica cu poliurie sau asociata cu diaree, varsaturi, insuficienta hepatica, nivelul ureei poate fi mai putin crescut decat cel anticipat. Pe de alta parte, in asocierea insuficientei renale cronice cu oligurie, aport proteic crescut, insuficienta cardiaca, hemoragie digestiva nivelul ureei este mai mare decat cel asteptat6<\/sup>.<\/p>\n

\u2022 Medicamente<\/p>\n

Cresteri<\/strong><\/span>: acetaminofen, acetazolamid, acid aminocaproic, acid nalidixic, acyclovir, albendazol, antiacide alcaline, alopurinol, amantadina, amikacin, amilorid, amiodarona, aminoacizi, amfotericina B, asparaginaza, aspirina, atenolol, azatioprin, azitromicina, bacitracin, benazepril, bisoprolol, busulfan, calcitriol, canabis, capreomicin, captopril, carbamazepin, carvedilol, caspofungin, cefaclor, cefamandol, cefazolin, cefixim, cefoperazon, cefotaxim, cefotetan, cefoxitin, cefpodoxim, ceftibuten, ceftizoxim, ceftriaxon, cefuroxim, cefalexin, cefaloridin, cefalotin, cetirizin, cloroform, clorotiazida, clorfeniramina, clortalidona, cimetidina, cinoxacin, ciprofloxacin, cisplatin, claritromicina, clindamicina, clonidina, codeina, cotrimoxazol, colistin, ciclosporina, dexametozona, dextran, diazepam, diazoxid, diclofenac, disopiramida, diuretice, doxorubicin, doxiciclina, enalapril, ergotamina, epoetin alfa, eprosartan, etambutol, eter, etidronat, etretinat, fenoprofen, flucitozin, fludarabina, foscarnet, furosemid, ganciclovir,\u00a0 gentamicina, griseofulvina, hidralazina, hidroclorotiazid, hidroxiuree, ibuprofen, idarubicin, ifosfamida, imipramina, indometacin, isotretinoin, kanamicina, ketoprofen, labetalol, leuprolid, levodopa, lidocaina, lisinopril, litiu, losartan, lovastatin, manitol, acid mefenamic, meropenem, meticilina, metisergid, metoprolol, metotrexat, metildopa, metilprednisolon, metoprolol, mitomicin, mitoxantron, moxalactam, naproxen, neomicina, netilmicina, nifedipina, nitrofurantoin, norfloxacin, ofloxacin, oxacilina, pamidronat, penicilamina, penicilina, pentamidina, pentostatin, piperacilina, piroxicam, preparate de fier, probenecid, propafenona, propranolol, rifampicina, ramipril, saruri de aur, spironolactona, streptokinaza, streptomicina, streptozocin, sulfametoxazol, sulfasalazina, sulindac, tacrolimus, tetraciclina, taliu, ticarcilina, ticlopidin, tobramicin, tramadol, trandolapril, tretinoin, triamteren, triazolam, trimetroprim, ursodiol, valsartan, vancomicin, vasopresin, vitamina D, zalcitabin2<\/sup>.<\/p>\n

Scaderi<\/strong><\/span>: acid ascorbic, fenotiazine2<\/sup>.<\/p>\n

\u00a0<\/span><\/p>\n

\u0411\u0438\u0431\u043b\u0438\u043e\u0433\u0440\u0430\u0444\u0438\u044f<\/span><\/p>\n

1. Frances Fischbach. Chemistry studies. In A Manual of Laboratory and Diagnostic Tests. Lippincott Williams & Wilkins, USA, 8 Ed., 2009, 369-370.<\/span><\/p>\n

2. Frances Fischbach. Effects of the Drugs on Laboratory Tests. In A Manual of Laboratory and Diagnostic Tests. Lippincott Williams & Wilkins, USA, 8 Ed., 2009; 1230-1231.<\/span><\/p>\n

3. Jacques Wallach. Analizele de sange. In Interpretarea testelor de diagnostic. Editura Stiintelor Medicale, Romania, 7 Ed., 2001; 110-111.<\/span><\/p>\n

4. Laborator Synevo. Referinte specifice tehnologiei de lucru utilizate 2015. Ref Type: Catalog.<\/span><\/p>\n

5. Laboratory Corporation of America. Directory of Services and Interpretive Guide. Urea Nitrogen, Serum. www.labcorp.com . 2010. Ref Type: Internet Communication.<\/span><\/p>\n

6. Lothar Thomas. Kidney and urinary tract. In Clinical Laboratory Diagnostics-Use and Assessment of Clinical laboratory Results. TH-Books Verlagsgesellschaft mbH, Frankfurt \/Main, Germany, 1 Ed., 1998, 374-377.<\/span><\/p>","protected":false},"excerpt":{"rendered":"

\u041c\u043e\u0447\u0435\u0432\u0438\u043d\u0430 – \u043a\u043e\u043d\u0435\u0447\u043d\u044b\u0439 \u043f\u0440\u043e\u0434\u0443\u043a\u0442 \u043c\u0435\u0442\u0430\u0431\u043e\u043b\u0438\u0437\u043c\u0430 \u0431\u0435\u043b\u043a\u043e\u0432 \u0432 \u043e\u0440\u0433\u0430\u043d\u0438\u0437\u043c\u0435. \u041e\u0441\u043d\u043e\u0432\u043d\u043e\u0435 \u043c\u0435\u0441\u0442\u043e \u043e\u0431\u0440\u0430\u0437\u043e\u0432\u0430\u043d\u0438\u044f \u043c\u043e\u0447\u0435\u0432\u0438\u043d\u044b – \u044d\u0442\u043e \u043f\u0435\u0447\u0435\u043d\u044c, \u043d\u043e, \u043e\u0434\u043d\u0430\u043a\u043e, \u0442\u043a\u0430\u043d\u044c \u0432 \u043f\u0440\u043e\u0446\u0435\u0441\u0441\u0435 \u0440\u043e\u0441\u0442\u0430 (\u043d\u0430\u043f\u0440\u0438\u043c\u0435\u0440, \u044d\u043c\u0431\u0440\u0438\u043e\u043d\u0430\u043b\u044c\u043d\u0430\u044f \u0442\u043a\u0430\u043d\u044c \u0438\u043b\u0438 \u043e\u043f\u0443\u0445\u043e\u043b\u0435\u0432\u0430\u044f \u0442\u043a\u0430\u043d\u044c) \u0438\u043c\u0435\u0435\u0442 \u0441\u0432\u043e\u0439\u0441\u0442\u0432\u043e \u043e\u0431\u0440\u0430\u0437\u043e\u0432\u044b\u0432\u0430\u0442\u044c \u043c\u043e\u0447\u0435\u0432\u0438\u043d\u0443 \u0438\u0437 \u0430\u0440\u0433\u0438\u043d\u0438\u043d\u0430. \u0411\u043e\u043b\u044c\u0448\u0438\u043d\u0441\u0442\u0432\u043e \u043c\u043e\u0447\u0435\u0432\u0438\u043d\u044b \u0432\u044b\u0432\u043e\u0434\u0438\u0442\u0441\u044f \u043f\u0443\u0442\u0435\u043c \u043a\u043b\u0443\u0431\u043e\u0447\u043a\u043e\u0432\u043e\u0439 \u0444\u0438\u043b\u044c\u0442\u0440\u0430\u0446\u0438\u0438; 40-60% \u043e\u0431\u0440\u0430\u0442\u043d\u043e \u0432\u0441\u0430\u0441\u044b\u0432\u0430\u0435\u0442\u0441\u044f \u0432 \u043a\u0440\u043e\u0432\u043e\u0442\u043e\u043a, \u0432 \u0437\u0430\u0432\u0438\u0441\u0438\u043c\u043e\u0441\u0442\u0438 \u043e\u0442 \u0441\u043a\u043e\u0440\u043e\u0441\u0442\u0438 \u0442\u043e\u043a\u0430 \u0432 \u043a\u0430\u043d\u0430\u043b\u044c\u0446\u0430\u0445 \u0438 \u043e\u0442 \u043a\u043e\u043d\u0446\u0435\u043d\u0442\u0440\u0430\u0446\u0438\u0438 \u0430\u043d\u0442\u0438\u0434\u0438\u0443\u0440\u0435\u0442\u0438\u0447\u0435\u0441\u043a\u043e\u0433\u043e \u0433\u043e\u0440\u043c\u043e\u043d\u0430 (\u0410\u0414\u0413).<\/p>\n

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\u0422\u0440\u0430\u043d\u0441\u043f\u043e\u0440\u0442\u043d\u0430\u044f\u00a0\u0441\u0440\u0435\u0434\u0430,\u00a0\u043f\u0440\u043e\u0431\u0438\u0440\u043a\u0430<\/b><\/td>\n\u0412\u0430\u043a\u0443\u0442\u0430\u0439\u043d\u0435\u0440\u00a0\u0441\/\u0431\u0435\u0437\u00a0\u0430\u043d\u0442\u0438\u043a\u043e\u0430\u0433\u0443\u043b\u044f\u043d\u0442\u0430\u00a0\u0441\/\u0431\u0435\u0437\u00a0\u0433\u0435\u043b\u0435\u0432\u043e\u0439\u00a0\u0444\u0430\u0437\u044b<\/td>\n<\/tr>\n
\u041f\u0440\u0430\u0432\u0438\u043b\u0430\u00a0\u0438\u00a0\u0443\u0441\u043b\u043e\u0432\u0438\u044f\u00a0\u0442\u0440\u0430\u043d\u0441\u043f\u043e\u0440\u0442\u0438\u0440\u043e\u0432\u043a\u0438,\u00a0\u0441\u0442\u0430\u0431\u0438\u043b\u044c\u043d\u043e\u0441\u0442\u044c\u00a0\u043f\u0440\u043e\u0431\u044b<\/b><\/td>\n\u0421\u0442\u0430\u043d\u0434\u0430\u0440\u0442\u043d\u044b\u0435<\/td>\n<\/tr>\n
\u041c\u0435\u0442\u043e\u0434\u00a0\u0442\u0435\u0441\u0442\u0438\u0440\u043e\u0432\u0430\u043d\u0438\u044f<\/b><\/td>\n\u041a\u0438\u043d\u0435\u0442\u0438\u0447\u0435\u0441\u043a\u0438\u0439<\/td>\n<\/tr>\n
<\/td>\n<\/td>\n<\/tr>\n
<\/td>\n<\/td>\n<\/tr>\n
<\/td>\n<\/td>\n<\/tr>\n
\u0418\u043d\u0442\u0435\u0440\u0444\u0435\u0440\u0438\u0440\u0443\u044e\u0449\u0438\u0435\u00a0\u0444\u0430\u043a\u0442\u043e\u0440\u044b.\u00a0\u041c\u0435\u0434\u0438\u043a\u0430\u043c\u0435\u043d\u0442\u044b<\/b><\/td>\n<\/tr>\n
\u041f\u043e\u0432\u044b\u0448\u0430\u044e\u0442<\/b><\/td>\n\u0421\u043d\u0438\u0436\u0430\u044e\u0442<\/b><\/td>\n<\/tr>\n
\u0410\u043c\u0438\u043d\u043e\u043a\u0430\u043f\u0440\u043e\u043d\u043e\u0432\u0430\u044f\u00a0\u043a\u0438\u0441\u043b\u043e\u0442\u0430,\u00a0\u043d\u0430\u043b\u0438\u0434\u0438\u043a\u0441\u043e\u0432\u0430\u044f\u00a0\u043a\u0438\u0441\u043b\u043e\u0442\u0430,\u00a0\u0430\u0446\u0438\u043a\u043b\u043e\u0432\u0438\u0440,<\/p>\n

\u0430\u043b\u043b\u043e\u043f\u0443\u0440\u0438\u043d\u043e\u043b,\u00a0\u0446\u0435\u0444\u0430\u0437\u043e\u043b\u0438\u043d,\u00a0\u0446\u0435\u0444\u0438\u043a\u0441\u0438\u043c,\u00a0\u0446\u0435\u0444\u043e\u043f\u0435\u0440\u0430\u0437\u043e\u043d,\u00a0\u0446\u0435\u0444\u043e\u0442\u0430\u043a\u0441\u0438\u043c,<\/p>\n

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\u043b\u0435\u0432\u043e\u0434\u043e\u043f\u0430,\u00a0\u043b\u0438\u0434\u043e\u043a\u0430\u0438\u043d,\u00a0\u043b\u043e\u0437\u0430\u0440\u0442\u0430\u043d,\u00a0\u043b\u043e\u0432\u0430\u0441\u0442\u0430\u0442\u0438\u043d,\u00a0\u043c\u0435\u0444\u0435\u043d\u0430\u043c\u043e\u0432\u0430\u044f\u00a0\u043a\u0438\u0441\u043b\u043e\u0442\u0430,<\/p>\n

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\u041f\u043e\u043a\u0430\u0437\u0430\u043d\u0438\u044f\u00a0\u043a\u00a0\u043d\u0430\u0437\u043d\u0430\u0447\u0435\u043d\u0438\u044e<\/b><\/td>\n<\/tr>\n
\u041c\u043e\u0447\u0435\u0432\u0438\u043d\u0430\u00a0—\u00a0\u043e\u0434\u0438\u043d\u00a0\u0438\u0437\u00a0\u043c\u0430\u0440\u043a\u0435\u0440\u043e\u0432\u00a0\u043d\u0430\u0440\u0443\u0448\u0435\u043d\u0438\u044f\u00a0\u0430\u0437\u043e\u0442\u0438\u0441\u0442\u043e\u0433\u043e\u00a0\u043e\u0431\u043c\u0435\u043d\u0430<\/b><\/p>\n

\u00b7\u00a0\u041d\u0430\u0440\u0443\u0448\u0435\u043d\u0438\u0435\u00a0\u0444\u0443\u043d\u043a\u0446\u0438\u0438\u00a0\u043f\u043e\u0447\u0435\u043a\u00a0\u0438\u00a0\u043f\u0435\u0447\u0435\u043d\u0438\u00a0(\u043f\u043e\u0447\u0435\u0447\u043d\u0430\u044f\u00a0\u0438\u00a0\u043f\u0435\u0447\u0435\u043d\u043e\u0447\u043d\u0430\u044f\u00a0\u043d\u0435\u0434\u043e\u0441\u0442\u0430\u0442\u043e\u0447\u043d\u043e\u0441\u0442\u044c);<\/p>\n

\u00b7\u00a0\u0434\u0438\u0444\u0444\u0435\u0440\u0435\u043d\u0446\u0438\u0430\u0446\u0438\u044f\u00a0\u043c\u0435\u0436\u0434\u0443\u00a0\u043f\u0440\u0435\u0440\u0435\u043d\u0430\u043b\u044c\u043d\u043e\u0439\u00a0\u0438\u00a0\u043f\u043e\u0441\u0442\u0440\u0435\u043d\u0430\u043b\u044c\u043d\u043e\u0439\u00a0\u0430\u0437\u043e\u0442\u0435\u043c\u0438\u0435\u0439\u00a0\u043d\u0430\u00a0\u043e\u0441\u043d\u043e\u0432\u0435\u00a0\u043e\u0442\u043d\u043e\u0448\u0435\u043d\u0438\u044f\u00a0\u043c\u043e\u0447\u0435\u0432\u0438\u043d\u0430\/\u043a\u0440\u0435\u0430\u0442\u0438\u043d\u0438\u043d;<\/p>\n

\u00b7\u00a0\u043c\u043e\u043d\u0438\u0442\u043e\u0440\u0438\u043d\u0433\u00a0\u044d\u0444\u0444\u0435\u043a\u0442\u0438\u0432\u043d\u043e\u0441\u0442\u0438\u00a0\u043d\u0438\u0437\u043a\u043e\u0431\u0435\u043b\u043a\u043e\u0432\u043e\u0439\u00a0\u0434\u0438\u0435\u0442\u044b\u00a0\u043f\u0440\u0438\u00a0\u0425\u041f\u041d;<\/p>\n

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\u0418\u043d\u0442\u0435\u0440\u043f\u0440\u0435\u0442\u0430\u0446\u0438\u044f\u00a0\u0440\u0435\u0437\u0443\u043b\u044c\u0442\u0430\u0442\u043e\u0432<\/b><\/td>\n<\/tr>\n
\u041f\u043e\u0432\u044b\u0448\u0435\u043d\u0438\u0435\u00a0\u0443\u0440\u043e\u0432\u043d\u044f<\/b><\/td>\n\u0421\u043d\u0438\u0436\u0435\u043d\u0438\u0435\u00a0\u0443\u0440\u043e\u0432\u043d\u044f<\/b><\/td>\n<\/tr>\n
\u00b7\u00a0\u0421\u043d\u0438\u0436\u0435\u043d\u0438\u0435\u00a0\u043f\u043e\u0447\u0435\u0447\u043d\u043e\u0439\u00a0\u043f\u0435\u0440\u0444\u0443\u0437\u0438\u0438\u00a0\u043f\u0440\u0438\u00a0\u0437\u0430\u0441\u0442\u043e\u0439\u043d\u043e\u0439\u00a0\u0441\u0435\u0440\u0434\u0435\u0447\u043d\u043e\u0439\u00a0\u043d\u0435\u0434\u043e\u0441\u0442\u0430\u0442\u043e\u0447\u043d\u043e\u0441\u0442\u0438,<\/p>\n

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\u00b7\u00a0\u0443\u0432\u0435\u043b\u0438\u0447\u0435\u043d\u0438\u0435\u00a0\u043a\u0430\u0442\u0430\u0431\u043e\u043b\u0438\u0437\u043c\u0430\u00a0\u0431\u0435\u043b\u043a\u0430:\u00a0\u043e\u0436\u043e\u0433\u0438,\u00a0\u0440\u0430\u043a,\u00a0\u0434\u043b\u0438\u0442\u0435\u043b\u044c\u043d\u044b\u0435<\/p>\n

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\u0442\u043e\u043a\u0441\u0438\u0447\u0435\u0441\u043a\u0438\u0435\u00a0\u0433\u0435\u043f\u0430\u0442\u0438\u0442\u044b,\u00a0\u0446\u0438\u0440\u0440\u043e\u0437,\u00a0\u043f\u0435\u0447\u0435\u043d\u043e\u0447\u043d\u0430\u044f\u00a0\u043a\u043e\u043c\u0430;<\/p>\n

\u00b7\u00a0\u0433\u0438\u043f\u0435\u0440\u0433\u0438\u0434\u0440\u0430\u0442\u0430\u0446\u0438\u044f\u00a0(\u0432\u00a0\u0442.\u0447.\u00a0\u043f\u0440\u0438\u00a0\u0447\u0440\u0435\u0437\u043c\u0435\u0440\u043d\u043e\u043c\u00a0\u0432\/\u0432\u00a0\u0432\u0432\u0435\u0434\u0435\u043d\u0438\u0438\u00a0\u0436\u0438\u0434\u043a\u043e\u0441\u0442\u0438);<\/p>\n

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\u00b7\u00a0\u0430\u043a\u0440\u043e\u043c\u0435\u0433\u0430\u043b\u0438\u044f;<\/p>\n

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\u00b7\u00a0\u0441\u043e\u0441\u0442\u043e\u044f\u043d\u0438\u0435\u00a0\u043f\u043e\u0441\u043b\u0435\u00a0\u0434\u0438\u0430\u043b\u0438\u0437\u0430;<\/p>\n

\u00b7\u00a0\u0434\u0435\u0442\u0441\u043a\u0438\u0439\u00a0\u0432\u043e\u0437\u0440\u0430\u0441\u0442;<\/p>\n

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