{"id":9241,"date":"2020-04-23T04:32:23","date_gmt":"2020-04-23T01:32:23","guid":{"rendered":"https:\/\/www.synevo.ro\/product\/fosfataza-alcalina\/"},"modified":"2026-02-19T01:14:40","modified_gmt":"2026-02-18T23:14:40","slug":"fosfataza-alcalina","status":"publish","type":"product","link":"https:\/\/old.synevo.md\/ru\/shop\/fosfataza-alcalina\/","title":{"rendered":"\u0429\u0435\u043b\u043e\u0447\u043d\u0430\u044f \u0444\u043e\u0441\u0444\u0430\u0442\u0430\u0437\u0430"},"content":{"rendered":"

\u041e\u0431\u0449\u0430\u044f \u0438\u043d\u0444\u043e\u0440\u043c\u0430\u0446\u0438\u044f<\/em><\/strong><\/p>\n

Fosfataza alcalina (ALP) este o enzima ce face parte din clasa hidrolazelor (ortofosfomonoesterfosfohidrolaza) si este alcatuita in principal din trei forme izoenzimatice (hepatobiliara, osoasa, intestinala), la care se adauga in timpul sarcinii o forma tranzitorie (forma placentara). Desi se poate face o evaluare rezonabila in privinta originii hepatice sau non-hepatice a cresterii fosfatazei alcaline utilizand doar date clinice, exista si metode biochimice ce pot face diferentierea intre izoenzime1;3<\/sup> .<\/p>\n

Recomandari pentru determinarea fosfatazei alcaline<\/em><\/strong><\/p>\n

Determinarea fosfatazei alcaline este de obicei folosita pentru diagnosticul diferential al bolilor hepatice. Alta arie de utilizari clinice include afectiunile osoase, fiind la ora actuala singura enzima cu importanta practica pentru patologia tesutului osos, si in hiperparatiroidism. In tumorile de diverse etiologii fosfataza alcalina are valoare de marker tumoral (depistarea metastazelor hepatice sau osoase)1;5<\/sup>.<\/p>\n

Pregatire pacient<\/em><\/strong> \u2013 \u00e0 jeun (pe nemancate)4<\/sup>.<\/p>\n

Specimen recoltat<\/em><\/strong> \u2013 sange venos4<\/sup>.<\/p>\n

Recipient de recoltare <\/em><\/strong>\u2013 vacutainer fara anticoagulant cu\/fara gel separator4<\/sup>.<\/p>\n

Prelucrare necesara dupa recoltare<\/em><\/strong> \u2013 se separa serul prin centrifugare4<\/sup>.<\/p>\n

Volum proba<\/em><\/strong> \u2013 minim 0.5 mL ser4<\/sup>.<\/p>\n

Cauze\u00a0 de respingere a probei<\/em><\/strong> \u2013 specimen intens hemolizat, lipemic sau contaminat bacterian4<\/sup>.<\/p>\n

Stabilitate proba <\/em><\/strong>\u2013 serul separat este stabil 7 zile<\/em> la temperatura camerei; 7 zile<\/em> la 4-8\u00b0C; 2 luni<\/em> la -20\u00b0C4<\/sup>.<\/p>\n

Metoda <\/em><\/strong>- spectrofotometrica (test colorimetric)<\/span>4<\/sup>.<\/p>\n

Valori de referinta <\/em><\/strong>\u2013 sunt dependente de varsta si sex4<\/sup>:<\/p>\n\n\n\n\n\n\n\n\n\n\n
\n

Varsta<\/em><\/strong><\/p>\n<\/td>\n

\n

Valori ( U\/L)<\/em><\/strong><\/p>\n<\/td>\n<\/tr>\n

\n

0-6 luni<\/p>\n<\/td>\n

\n

<449<\/p>\n<\/td>\n<\/tr>\n

\n

7-12 luni<\/p>\n<\/td>\n

\n

<462<\/p>\n<\/td>\n<\/tr>\n

\n

1-3 ani<\/p>\n<\/td>\n

\n

<281<\/p>\n<\/td>\n<\/tr>\n

\n

4-6 ani<\/p>\n<\/td>\n

\n

<269<\/p>\n<\/td>\n<\/tr>\n

\n

7-12 ani<\/p>\n<\/td>\n

\n

<300<\/p>\n<\/td>\n<\/tr>\n

\n

\u041d<\/strong>: 13-17 ani<\/p>\n

\u0415<\/strong>:\u00a0 13-17 ani<\/p>\n<\/td>\n

\n

\u00a0\u00a0\u00a0\u00a0 <390<\/p>\n

<187<\/p>\n<\/td>\n<\/tr>\n

\n

\u041d<\/strong>: >17 ani<\/p>\n

\u0415<\/strong>:\u00a0 >17ani<\/p>\n<\/td>\n

\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <129\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 \u00a0<104<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Factor de conversie: U\/L x 0.0167 = \u00b5kat\/L.<\/em><\/p>\n

Limita de detectie<\/em><\/strong> - <\/em>0.67U\/L(0.011 \u00b5kat\/L)4<\/sup>.\u00a0<\/em><\/p>\n

Valorile mai mari inregistrate la copii se asociaza cu perioada de crestere osoasa.<\/p>\n

Interpretarea rezultatelor<\/em><\/strong><\/p>\n\n\n\n\n\n\n
\n

Cresteri<\/em><\/strong><\/p>\n<\/td>\n<\/tr>\n

\u2022 Valori crescute de origine hepatica<\/em>: cele mai marcate cresteri se intalnesc in obstructia mecanica a cailor biliare extrahepatice sau in colestaza intrahepatica:<\/p>\n

\u2013 o crestere de 10 ori \u2013 in cancer de cap de pancreas, litiaza coledociana, hepatita colestatica medicamentoasa;<\/p>\n

\u2013 o crestere de 5-20 ori \u2013 in ciroza biliara primitiva, carcinoame hepatice primare sau metastatice;<\/p>\n

\u2013 cresteri usoare\/moderate (de 2 ori normalul) se inregistreaza in hepatita virala si ciroza;<\/p>\n

\u2013 in mononucleoza infectioasa si in infectia cu citomegalovirus pot aparea cresteri de pana la 5 ori normalul;<\/p>\n

\u2013 in ingestia cronica de alcool fosfataza alcalina poate avea valoare normala sau crescuta, sunt insa constant crescute GGT, AST si eventual bilirubina5<\/sup>;<\/p>\n

\u2013 valori crescute mai pot aparea in bolile hepatice de cauza infiltrativa (sarcoidoza, tuberculoza, amiloidoza, abcese)1<\/sup>.<\/p>\n

\u2022\u00a0 Valori crescute de origine osoasa<\/em>: hiperparatiroidism; hipertiroidism; boala Paget; metastaze osoase; tumori osoase; osteomalacie, rahitism; in evolutia fracturilor multiple1<\/sup>.<\/p>\n

\u2022\u00a0 Valori crescute de origine placentara<\/em>: apar in saptamanile 16-20 ale unei sarcini normale, crescand pana la nivelul maxim (de 2 ori normalul) la debutul travaliului5<\/sup>.<\/p>\n

\u2022 Valori crescute de origine intestinala<\/em>: in diverse afectiuni ulcerative ale tractului gastrointestinal, malabsorbtie severa, infarct intestinal.<\/p>\n

\u2022 Valori crescute in neoplasme<\/em>: ocazional tumorile (in special hipernefromul) pot produce o fosfataza alcalina identica sau similara cu forma placentara (izoenzima Regan)5<\/sup>.\u00a0<\/em><\/strong><\/td>\n<\/tr>\n

\n

Scaderi<\/em><\/strong><\/p>\n<\/td>\n<\/tr>\n

\n

\u2022 hipofosfatazia familiala; \u2022 hipotiroidism, cretinism; \u2022 malnutritie; \u2022 deficit de zinc; \u2022 deficit de magneziu; \u2022 femeile aflate in post menopauza cu osteoporoza care urmeaza tratament estrogenic substitutiv1;3<\/sup>.<\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Limite si interferente<\/em><\/strong><\/p>\n

Valoarea ALP interpretata izolat poate crea confuzii de diagnostic. Determinarea GGT reprezinta un test suplimentar util, pentru a confirma originea hepato-biliara a fosfatazei alcaline crescute in prezenta unor valori normale ale transaminazelor.<\/p>\n

\u2022 Medicamente<\/p>\n

Cresteri<\/strong><\/span><\/p>\n

Medicamente care produc colestaza<\/em>: acid aminosalicilic, amitriptilina, steroizi anabolizanti, androgeni, azatioprina, benzodiazepine, carbamazepin, carbazona, clorotiazida, clorpropamida, acid clavulanic, dapsona.<\/p>\n

Medicamente care produc afectare hepatocelulara<\/em>: acetaminofen, alopurinol, acid aminosalicilic, amiodarona, amitriptilina, steroizi anabolizanti, androgeni, asparaginaza, aspirina, azatioprina, carbamazepin, chenodiol, clorambucil, cloramfenicol, clorpropamida, cimetidina, ciclosporina, danazol, dantrolen, dapsona, diclofenac, dicumarol (rar), disulfiram, eritromicina, estrogeni, etionamida, gliburid (glibenclamid), saruri de aur, imipramina, mercaptopurina, metimazol, acid nicotinic, nitrofurantoin, contraceptive orale, estrogeni, etanol (exces), etionamida, fluconazol, halotan, ibuprofen, imipramina, indometacin, saruri de fier (supradozare), izoniazida, ketoconazol, inhibitori de MAO, mercaptopurina, metotrexat, metoxifluran, metildopa, naproxen, papaverina, parametadion, penicilamina, peniciline, fenotiazine, fenilbutazona, progestative, propoxifen, sulfonamide, sulfone, sulindac, tamoxifen, tolbutamida, perhexilin, fenazopiridina, fenidiona, fenobarbital, fenilbutazona, fenitoin, plicamicina (mitramicina), probenecid, procainamida, propiltiouracil, pirazinamida, chinidina, rifampicina, salicilati, sulfasalazina, sulfonamide, tamoxifen, tetracicline, trimetadiona, acid valproic, vitamina A, warfarina (rar).<\/p>\n

Multe alte medicamente pot determina cresteri<\/em> care, in general, sunt tranzitorii, dar in anumite cazuri indica hepatotoxicitate. Acestea includ: acebutolol, aminoglutetimid, aminoglicozide, bromocriptina, carboplatin, captopril, cefalosporine, clindamicin, clotrimazol, colchicina, ciclosporina, citarabina, dapsona,\u00a0 desipramina, dicumarol, didanosin, disopiramid, enalapril, etambutol, etopozid, filgrastim, flucitozin, foscarnet, ganciclovir, gentamicina, interferon, izotretinoin, ketoconazol, labetolol, levamisol, lincomicina, mebenzadol, mefenitoin, nifedipin, antiinflamatoare nesteroidiene (ex.: ibuprofen, naproxen), omeprazol, ondansetron, peniciline, fenitoina, propoxifen, protriptilina, streptozocin, sulfoniluree, tioguanina, ticlopidina, verapamil, zalcitabin2<\/sup>.<\/p>\n

Scaderi<\/strong><\/span>: acyclovir, azatioprina, calcitriol, ciclosporina, contraceptive orale, clofibrat, danazol, estrogeni, pamidronat, penicilamina, prednisolon, prednison, tamoxifen, ursodiol, vitamina D2<\/sup>.<\/p>\n

\u2022 Interferente analitice<\/p>\n

Hemoliza intensa poate genera valori fals scazute ale fosfatazei alcaline4<\/sup>.<\/p>\n

\u00a0<\/span><\/p>\n

\u0411\u0438\u0431\u043b\u0438\u043e\u0433\u0440\u0430\u0444\u0438\u044f<\/span><\/p>\n

1. Frances Fischbach. Chemistry Studies. In A Manual of Laboratory and Diagnostic Tests. Lippincott Williams & Wilkins, USA, 8 Ed., 2009; 413-415.<\/span><\/p>\n

2. Frances Fischbach. Effects of the Drugs on Laboratory Tests. In A Manual of Laboratory and Diagnostic Tests. Lippincott Williams & Wilkins, USA, 8 Ed., 2009; 1222-1223.<\/span><\/p>\n

3. Jacques Wallach. Analizele de sange. In Interpretarea testelor de diagnostic. Editura Stiintelor Medicale, Romania, 7 Ed., 2001; 73-76.<\/span><\/p>\n

4. Laborator Synevo. Referintele specifice tehnologiei de lucru utilizate. 2010. Ref Type: Catalog.<\/span><\/p>\n

5. Laboratory Corporation of America. Directory of Services and Interpretive Guide. Alkaline Phosphatase, Serum. www.labcorp.com . 2010. Ref Type: Internet Communication.<\/span><\/p>","protected":false},"excerpt":{"rendered":"

\u0429\u0435\u043b\u043e\u0447\u043d\u0430\u044f \u0444\u043e\u0441\u0444\u0430\u0442\u0430\u0437\u0430\u00a0 – \u0444\u0435\u0440\u043c\u0435\u043d\u0442 \u043a\u043b\u0430\u0441\u0441\u0430 \u0433\u0438\u0434\u0440\u043e\u043b\u0430\u0437 (\u043e\u0440\u0442\u043e\u0444\u043e\u0441\u0444\u043e\u043c\u043e\u043d\u043e\u044d\u0441\u0442\u0435\u0440\u0444\u043e\u0441\u0444\u043e\u0433\u0438\u0434\u0440\u043e\u043b\u0430\u0437\u0430), \u0432 \u043e\u0441\u043d\u043e\u0432\u043d\u043e\u043c, \u0441\u043e\u0441\u0442\u043e\u0438\u0442 \u0438\u0437 \u0442\u0440\u0435\u0445 \u0438\u0437\u043e\u0444\u0435\u0440\u043c\u0435\u043d\u0442\u043d\u044b\u0445 \u0444\u043e\u0440\u043c (\u0433\u0435\u043f\u0430\u0442\u043e\u0431\u0438\u043b\u0438\u0430\u0440\u043d\u043e\u0439, \u043a\u043e\u0441\u0442\u043d\u043e\u0439, \u043a\u0438\u0448\u0435\u0447\u043d\u043e\u0439), \u0432\u043e \u0432\u0440\u0435\u043c\u044f \u0431\u0435\u0440\u0435\u043c\u0435\u043d\u043d\u043e\u0441\u0442\u0438 \u043f\u043e\u044f\u0432\u043b\u044f\u0435\u0442\u0441\u044f \u043f\u0435\u0440\u0435\u0445\u043e\u0434\u043d\u0430\u044f \u043f\u043b\u0430\u0446\u0435\u043d\u0442\u0430\u0440\u043d\u0430\u044f \u0444\u043e\u0440\u043c\u0430. \u0429\u0435\u043b\u043e\u0447\u043d\u0430\u044f \u0444\u043e\u0441\u0444\u0430\u0442\u0430\u0437\u0430 \u043a\u0430\u0442\u0430\u043b\u0438\u0437\u0438\u0440\u0443\u0435\u0442 \u043e\u0442\u0449\u0435\u043f\u043b\u0435\u043d\u0438\u0435 \u0444\u043e\u0441\u0444\u043e\u0440\u043d\u043e\u0439 \u043a\u0438\u0441\u043b\u043e\u0442\u044b \u043e\u0442 \u0435\u0435 \u043e\u0440\u0433\u0430\u043d\u0438\u0447\u0435\u0441\u043a\u0438\u0445 \u0441\u043e\u0435\u0434\u0438\u043d\u0435\u043d\u0438\u0439, \u0444\u0435\u0440\u043c\u0435\u043d\u0442 \u0440\u0430\u0441\u043f\u043e\u043b\u043e\u0436\u0435\u043d \u043d\u0430 \u043a\u043b\u0435\u0442\u043e\u0447\u043d\u043e\u0439 \u043c\u0435\u043c\u0431\u0440\u0430\u043d\u0435 \u0438 \u043f\u0440\u0438\u043d\u0438\u043c\u0430\u0435\u0442 \u0443\u0447\u0430\u0441\u0442\u0438\u0435 \u0432 \u0442\u0440\u0430\u043d\u0441\u043f\u043e\u0440\u0442\u0435 \u0444\u043e\u0441\u0444\u043e\u0440\u0430.<\/p>\n

\u0429\u0435\u043b\u043e\u0447\u043d\u0430\u044f \u0444\u043e\u0441\u0444\u0430\u0442\u0430\u0437\u0430 \u0443\u0447\u0430\u0441\u0442\u0432\u0443\u0435\u0442 \u0432 \u043f\u0440\u043e\u0446\u0435\u0441\u0441\u0430\u0445, \u0441\u0432\u044f\u0437\u0430\u043d\u043d\u044b\u0445 \u0441 \u0440\u043e\u0441\u0442\u043e\u043c \u043a\u043e\u0441\u0442\u0435\u0439, \u043f\u043e\u044d\u0442\u043e\u043c\u0443 \u0430\u043a\u0442\u0438\u0432\u043d\u043e\u0441\u0442\u044c \u0435\u0451 \u0432 \u0441\u044b\u0432\u043e\u0440\u043e\u0442\u043a\u0435 \u0434\u0435\u0442\u0435\u0439 \u0432\u044b\u0448\u0435, \u0447\u0435\u043c \u0443 \u0432\u0437\u0440\u043e\u0441\u043b\u044b\u0445. \u041f\u0430\u0442\u043e\u043b\u043e\u0433\u0438\u0447\u0435\u0441\u043a\u043e\u0435 \u043f\u043e\u0432\u044b\u0448\u0435\u043d\u0438\u0435 \u0430\u043a\u0442\u0438\u0432\u043d\u043e\u0441\u0442\u0438 \u0449\u0435\u043b\u043e\u0447\u043d\u043e\u0439 \u0444\u043e\u0441\u0444\u0430\u0442\u0430\u0437\u044b \u0432 \u0441\u044b\u0432\u043e\u0440\u043e\u0442\u043a\u0435 \u0441\u0432\u044f\u0437\u0430\u043d\u043e, \u0432 \u043e\u0441\u043d\u043e\u0432\u043d\u043e\u043c, \u0441 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u044f\u043c\u0438 \u043a\u043e\u0441\u0442\u0435\u0439 (\u0444\u043e\u0440\u043c\u0438\u0440\u043e\u0432\u0430\u043d\u0438\u0435\u043c \u043a\u043e\u0441\u0442\u043d\u043e\u0439 \u0442\u043a\u0430\u043d\u0438) \u0438 \u043f\u0435\u0447\u0435\u043d\u0438 (\u043e\u0431\u0441\u0442\u0440\u0443\u043a\u0446\u0438\u0435\u0439 \u0436\u0435\u043b\u0447\u043d\u044b\u0445 \u043f\u0440\u043e\u0442\u043e\u043a\u043e\u0432). \u0423 \u043d\u0435\u0434\u043e\u043d\u043e\u0448\u0435\u043d\u043d\u044b\u0445, \u0434\u0435\u0442\u0435\u0439 \u0432 \u043f\u0435\u0440\u0438\u043e\u0434 \u0430\u043a\u0442\u0438\u0432\u043d\u043e\u0433\u043e \u0440\u043e\u0441\u0442\u0430, \u0431\u0435\u0440\u0435\u043c\u0435\u043d\u043d\u044b\u0445 (\u0442\u0440\u0435\u0442\u0438\u0439 \u0442\u0440\u0438\u043c\u0435\u0441\u0442\u0440) \u043c\u043e\u0436\u0435\u0442 \u043d\u0430\u0431\u043b\u044e\u0434\u0430\u0442\u044c\u0441\u044f \u043f\u043e\u0432\u044b\u0448\u0435\u043d\u043d\u0430\u044f \u0444\u0438\u0437\u0438\u043e\u043b\u043e\u0433\u0438\u0447\u0435\u0441\u043a\u0430\u044f \u0430\u043a\u0442\u0438\u0432\u043d\u043e\u0441\u0442\u044c \u0449\u0435\u043b\u043e\u0447\u043d\u043e\u0439 \u0444\u043e\u0441\u0444\u0430\u0442\u0430\u0437\u044b. \u041f\u0440\u043e\u0432\u043e\u0434\u0438\u0442\u044c \u043e\u0431\u044a\u0435\u043a\u0442\u0438\u0432\u043d\u0443\u044e \u043e\u0446\u0435\u043d\u043a\u0443 \u0432 \u043e\u0442\u043d\u043e\u0448\u0435\u043d\u0438\u0438 \u043f\u0435\u0447\u0435\u043d\u043e\u0447\u043d\u043e\u0433\u043e \u0438\u043b\u0438 \u043d\u0435\u043f\u0435\u0447\u0435\u043d\u043e\u0447\u043d\u043e\u0433\u043e \u043f\u0440\u043e\u0438\u0441\u0445\u043e\u0436\u0434\u0435\u043d\u0438\u044f \u0440\u043e\u0441\u0442\u0430 \u0443\u0440\u043e\u0432\u043d\u044f \u0449\u0435\u043b\u043e\u0447\u043d\u043e\u0439 \u0444\u043e\u0441\u0444\u0430\u0442\u0430\u0437\u044b \u043d\u0435\u043e\u0431\u0445\u043e\u0434\u0438\u043c\u043e \u0438\u0441\u043f\u043e\u043b\u044c\u0437\u0443\u044f \u043a\u043b\u0438\u043d\u0438\u0447\u0435\u0441\u043a\u0438\u0435 \u0434\u0430\u043d\u043d\u044b\u0435, \u043e\u0434\u043d\u0430\u043a\u043e \u0441\u0443\u0449\u0435\u0441\u0442\u0432\u0443\u044e\u0442 \u0438 \u0431\u0438\u043e\u0445\u0438\u043c\u0438\u0447\u0435\u0441\u043a\u0438\u0435 \u043c\u0435\u0442\u043e\u0434\u044b, \u043a\u043e\u0442\u043e\u0440\u044b\u0435 \u043c\u043e\u0433\u0443\u0442 \u043f\u0440\u043e\u0432\u043e\u0434\u0438\u0442\u044c \u0434\u0438\u0444\u0444\u0435\u0440\u0435\u043d\u0446\u0438\u0430\u0446\u0438\u044e \u043c\u0435\u0436\u0434\u0443 \u0438\u0437\u043e\u0444\u0435\u0440\u043c\u0435\u043d\u0442\u0430\u043c\u0438.<\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
\u041f\u043e\u043a\u0430\u0437\u0430\u0442\u0435\u043b\u044c<\/b><\/td>\n\u0425\u0430\u0440\u0430\u043a\u0442\u0435\u0440\u0438\u0441\u0442\u0438\u043a\u0430<\/b><\/td>\n<\/tr>\n
\u041c\u0430\u0442\u0435\u0440\u0438\u0430\u043b<\/b><\/td>\n\u0412\u0435\u043d\u043e\u0437\u043d\u0430\u044f\u00a0\u043a\u0440\u043e\u0432\u044c<\/td>\n<\/tr>\n
\u041f\u0440\u0430\u0432\u0438\u043b\u0430\u00a0\u043f\u043e\u0434\u0433\u043e\u0442\u043e\u0432\u043a\u0438\u00a0\u043f\u0430\u0446\u0438\u0435\u043d\u0442\u0430<\/b><\/td>\n\u0421\u0442\u0430\u043d\u0434\u0430\u0440\u0442\u043d\u044b\u0435<\/td>\n<\/tr>\n
\u0422\u0440\u0430\u043d\u0441\u043f\u043e\u0440\u0442\u043d\u0430\u044f\u00a0\u0441\u0440\u0435\u0434\u0430,\u00a0\u043f\u0440\u043e\u0431\u0438\u0440\u043a\u0430<\/b><\/td>\n\u0412\u0430\u043a\u0443\u0442\u0430\u0439\u043d\u0435\u0440\u00a0\u0441\/\u0431\u0435\u0437\u00a0\u0430\u043d\u0442\u0438\u043a\u043e\u0430\u0433\u0443\u043b\u044f\u043d\u0442\u0430\u00a0\u0441\/\u0431\u0435\u0437\u00a0\u0433\u0435\u043b\u0435\u0432\u043e\u0439\u00a0\u0444\u0430\u0437\u044b<\/td>\n<\/tr>\n
\u041f\u0440\u0430\u0432\u0438\u043b\u0430\u00a0\u0438\u00a0\u0443\u0441\u043b\u043e\u0432\u0438\u044f\u00a0\u0442\u0440\u0430\u043d\u0441\u043f\u043e\u0440\u0442\u0438\u0440\u043e\u0432\u043a\u0438,\u00a0\u0441\u0442\u0430\u0431\u0438\u043b\u044c\u043d\u043e\u0441\u0442\u044c\u00a0\u043f\u0440\u043e\u0431\u044b<\/b><\/td>\n\u0421\u0442\u0430\u043d\u0434\u0430\u0440\u0442\u043d\u044b\u0435<\/td>\n<\/tr>\n
\u041c\u0435\u0442\u043e\u0434\u00a0\u0442\u0435\u0441\u0442\u0438\u0440\u043e\u0432\u0430\u043d\u0438\u044f<\/b><\/td>\n\u041a\u043e\u043b\u043e\u0440\u0438\u043c\u0435\u0442\u0440\u0438\u0447\u0435\u0441\u043a\u0438\u0439<\/td>\n<\/tr>\n
<\/td>\n<\/td>\n<\/tr>\n
<\/td>\n<\/tr>\n
<\/td>\n<\/td>\n<\/tr>\n
\u0418\u043d\u0442\u0435\u0440\u0444\u0435\u0440\u0438\u0440\u0443\u044e\u0449\u0438\u0435\u00a0\u0444\u0430\u043a\u0442\u043e\u0440\u044b.\u00a0\u041c\u0435\u0434\u0438\u043a\u0430\u043c\u0435\u043d\u0442\u044b<\/b><\/td>\n<\/tr>\n
\u041f\u043e\u0432\u044b\u0448\u0430\u044e\u0442<\/b><\/td>\n\u0421\u043d\u0438\u0436\u0430\u044e\u0442<\/b><\/td>\n<\/tr>\n
\u0410\u0437\u0430\u0442\u0438\u043e\u043f\u0440\u0438\u043d,\u00a0\u043a\u0430\u0440\u0431\u0430\u0437\u043e\u043d,\u00a0\u0430\u043d\u0434\u0440\u043e\u0433\u0435\u043d\u044b,\u00a0\u0431\u0435\u043d\u0437\u043e\u0434\u0438\u0430\u0437\u0435\u043f\u0438\u043d\u044b,<\/p>\n

\u0438\u043c\u0438\u043f\u0440\u0430\u043c\u0438\u043d,\u043a\u0430\u0440\u0431\u0430\u043c\u0430\u0437\u0435\u043f\u0438\u043d,\u00a0\u043c\u0435\u043f\u0440\u043e\u0431\u0430\u043c\u0430\u0442,\u00a0\u043c\u0435\u0440\u043a\u0430\u0437\u043e\u043b\u0438\u043b,<\/p>\n

\u043d\u0438\u043a\u043e\u0442\u0438\u043d\u043e\u0432\u0430\u044f\u00a0\u043a\u0438\u0441\u043b\u043e\u0442\u0430,\u00a0\u043f\u0435\u043d\u0438\u0446\u0438\u043b\u043b\u0438\u043d\u044b,\u00a0\u043f\u0435\u0440\u043e\u0440\u0430\u043b\u044c\u043d\u044b\u0435\u00a0\u043a\u043e\u043d\u0442\u0440\u0430\u0446\u0435\u043f\u0442\u0438\u0432\u044b,<\/p>\n

\u043f\u0440\u043e\u0433\u0435\u0441\u0442\u0438\u043d\u044b,\u00a0\u0441\u0443\u043b\u044c\u0444\u0430\u0442\u044b,\u00a0\u0441\u0443\u043b\u044c\u0444\u0430\u043d\u0438\u043b\u0430\u043c\u0438\u0434\u044b,\u00a0\u0444\u0435\u043d\u043e\u0442\u0438\u0430\u0437\u0438\u043d\u044b,<\/p>\n

\u044d\u0440\u0438\u0442\u0440\u043e\u043c\u0438\u0446\u0438\u043d,\u00a0\u044d\u0441\u0442\u0440\u043e\u0433\u0435\u043d\u044b,\u00a0\u043c\u0435\u0442\u043e\u0442\u0440\u0435\u043a\u0441\u0430\u0442,\u00a0\u0445\u043b\u043e\u0440\u043f\u0440\u043e\u043c\u0430\u0437\u0438\u043d,<\/p>\n

\u0430\u043d\u0442\u0438\u0431\u0438\u043e\u0442\u0438\u043a\u0438\u00a0\u0448\u0438\u0440\u043e\u043a\u043e\u0433\u043e\u00a0\u0441\u043f\u0435\u043a\u0442\u0440\u0430\u00a0\u0434\u0435\u0439\u0441\u0442\u0432\u0438\u044f,\u00a0\u0441\u0443\u043b\u044c\u0444\u0430\u043d\u0438\u043b\u0430\u043c\u0438\u0434\u044b,<\/p>\n

\u0431\u043e\u043b\u044c\u0448\u0438\u0435\u00a0\u0434\u043e\u0437\u044b\u00a0\u0432\u0438\u0442\u0430\u043c\u0438\u043d\u0430\u00a0\u0421,\u00a0\u043c\u0430\u0433\u043d\u0435\u0437\u0438\u0438<\/td>\n

\u0424\u0442\u043e\u0440\u0438\u0434\u044b,\u00a0\u043e\u043a\u0441\u0430\u043b\u0430\u0442\u044b,\u00a0\u0444\u043e\u0441\u0444\u0430\u0442\u044b,\u00a0\u0431\u0435\u0440\u0438\u043b\u043b\u0438\u0439,\u00a0\u0441\u043e\u043b\u0438\u00a0\u0446\u0438\u043d\u043a\u0430,\u00a0\u043c\u0430\u0440\u0433\u0430\u043d\u0435\u0446,\u00a0\u0430\u0440\u0441\u0435\u043d\u0438\u0442\u044b,<\/p>\n

\u0446\u0438\u0442\u0440\u0430\u0442\u044b,\u00a0\u0446\u0438\u0430\u043d\u0438\u0434\u044b,\u00a0\u0442\u0438\u043e\u0441\u0443\u043b\u044c\u0444\u0430\u0442\u044b,\u00a0\u042d\u0414\u0422\u0410,\u00a0\u044d\u0441\u0442\u0440\u043e\u0433\u0435\u043d\u044b,\u00a0\u043e\u0440\u0430\u043b\u044c\u043d\u044b\u0435\u00a0\u043a\u043e\u043d\u0442\u0440\u0430\u0446\u0435\u043f\u0442\u0438\u0432\u044b,<\/p>\n

\u0434\u0430\u043d\u0430\u0437\u043e\u043b,\u00a0\u0430\u0437\u0430\u0442\u0438\u043e\u043f\u0440\u0438\u043d,\u00a0\u043a\u043b\u043e\u0444\u0438\u0431\u0440\u0430\u0442<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\n\n\n\n\n\n\n
\u041f\u043e\u043a\u0430\u0437\u0430\u043d\u0438\u044f\u00a0\u043a\u00a0\u043d\u0430\u0437\u043d\u0430\u0447\u0435\u043d\u0438\u044e<\/b><\/td>\n<\/tr>\n
\u0429\u0435\u043b\u043e\u0447\u043d\u0430\u044f\u00a0\u0444\u043e\u0441\u0444\u0430\u0442\u0430\u0437\u0430\u00a0—\u00a0\u043e\u0434\u0438\u043d\u00a0\u0438\u0437\u00a0\u043f\u043e\u043a\u0430\u0437\u0430\u0442\u0435\u043b\u0435\u0439\u00a0\u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u044f\u00a0\u043f\u0435\u0447\u0435\u043d\u0438\u00a0\u0438\u00a0\u043a\u043e\u0441\u0442\u043d\u043e\u0439\u00a0\u0442\u043a\u0430\u043d\u0438<\/b><\/p>\n

\u00b7\u00a0\u041f\u0430\u0442\u043e\u043b\u043e\u0433\u0438\u044f\u00a0\u043a\u043e\u0441\u0442\u043d\u043e\u0439\u00a0\u0442\u043a\u0430\u043d\u0438;<\/p>\n

\u00b7\u00a0\u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u044f\u00a0\u043f\u0435\u0447\u0435\u043d\u0438\u00a0\u0438\u00a0\u0436\u0435\u043b\u0447\u0435\u0432\u044b\u0432\u043e\u0434\u044f\u0449\u0438\u0445\u00a0\u043f\u0443\u0442\u0435\u0439,\u00a0\u0432\u00a0\u0442\u043e\u043c\u00a0\u0447\u0438\u0441\u043b\u0435\u00a0\u0441\u043e\u043f\u0440\u043e\u0432\u043e\u0436\u0434\u0430\u044e\u0449\u0438\u0435\u0441\u044f\u00a0\u043e\u0431\u0441\u0442\u0440\u0443\u043a\u0442\u0438\u0432\u043d\u044b\u043c\u00a0\u0441\u0438\u043d\u0434\u0440\u043e\u043c\u043e\u043c<\/td>\n<\/tr>\n

\u0418\u043d\u0442\u0435\u0440\u043f\u0440\u0435\u0442\u0430\u0446\u0438\u044f\u00a0\u0440\u0435\u0437\u0443\u043b\u044c\u0442\u0430\u0442\u043e\u0432<\/b><\/td>\n<\/tr>\n
\u041f\u043e\u0432\u044b\u0448\u0435\u043d\u0438\u0435\u00a0\u0443\u0440\u043e\u0432\u043d\u044f<\/b><\/td>\n\u0421\u043d\u0438\u0436\u0435\u043d\u0438\u0435\u00a0\u0443\u0440\u043e\u0432\u043d\u044f<\/b><\/td>\n<\/tr>\n
\u00b7\u00a0\u041f\u0430\u0442\u043e\u043b\u043e\u0433\u0438\u044f\u00a0\u043a\u043e\u0441\u0442\u043d\u043e\u0439\u00a0\u0442\u043a\u0430\u043d\u0438\u00a0(\u0434\u0435\u0444\u043e\u0440\u043c\u0438\u0440\u0443\u044e\u0449\u0438\u0439\u00a0\u043e\u0441\u0442\u0435\u0438\u0442,\u00a0\u043e\u0441\u0442\u0435\u043e\u043c\u0430\u043b\u044f\u0446\u0438\u044f,<\/p>\n

\u0431\u043e\u043b\u0435\u0437\u043d\u044c\u00a0\u0413\u043e\u0448\u0435\u00a0\u0441\u00a0\u0440\u0435\u0437\u043e\u0440\u0431\u0446\u0438\u0435\u0439\u00a0\u043a\u043e\u0441\u0442\u0435\u0439,\u00a0\u043e\u0441\u0442\u0435\u043e\u0441\u0430\u0440\u043a\u043e\u043c\u0430,<\/p>\n

\u043c\u0435\u0442\u0430\u0441\u0442\u0430\u0437\u044b\u00a0\u043e\u043f\u0443\u0445\u043e\u043b\u0435\u0439\u00a0\u0432\u00a0\u043a\u043e\u0441\u0442\u0438,\u00a0\u043f\u0435\u0440\u0438\u043e\u0434\u00a0\u0437\u0430\u0436\u0438\u0432\u043b\u0435\u043d\u0438\u044f\u00a0\u043f\u0435\u0440\u0435\u043b\u043e\u043c\u043e\u0432);<\/p>\n

\u00b7\u00a0\u0440\u0430\u0445\u0438\u0442;<\/p>\n

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\u0438\u043d\u0444\u0435\u043a\u0446\u0438\u043e\u043d\u043d\u044b\u0435,\u00a0\u0442\u043e\u043a\u0441\u0438\u0447\u0435\u0441\u043a\u0438\u0435,\u00a0\u043b\u0435\u043a\u0430\u0440\u0441\u0442\u0432\u0435\u043d\u043d\u044b\u0435\u00a0\u0433\u0435\u043f\u0430\u0442\u0438\u0442\u044b,\u00a0\u0441\u0430\u0440\u043a\u043e\u0438\u0434\u043e\u0437<\/p>\n

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\u00b7\u00a0\u0432\u043d\u0443\u0442\u0440\u0438-\u00a0\u0438\u00a0\u0432\u043d\u0435\u043f\u0435\u0447\u0435\u043d\u043e\u0447\u043d\u044b\u0439\u00a0\u0445\u043e\u043b\u0435\u0441\u0442\u0430\u0437\u00a0(\u0445\u043e\u043b\u0430\u043d\u0433\u0438\u0442\u044b,\u00a0\u043a\u0430\u043c\u043d\u0438\u00a0\u0436\u0435\u043b\u0447\u043d\u044b\u0445\u00a0\u043f\u0440\u043e\u0442\u043e\u043a\u043e\u0432\u00a0\u0438<\/p>\n

\u0436\u0435\u043b\u0447\u043d\u043e\u0433\u043e\u00a0\u043f\u0443\u0437\u044b\u0440\u044f,\u00a0\u043e\u043f\u0443\u0445\u043e\u043b\u0438\u00a0\u0436\u0435\u043b\u0447\u0435\u0432\u044b\u0432\u043e\u0434\u044f\u0449\u0438\u0445\u00a0\u043f\u0443\u0442\u0435\u0439);<\/p>\n

\u00b7\u00a0\u043d\u0430\u0440\u0443\u0448\u0435\u043d\u0438\u044f\u00a0\u043f\u0438\u0442\u0430\u043d\u0438\u044f\u00a0(\u043d\u0435\u0434\u043e\u0441\u0442\u0430\u0442\u043e\u043a\u00a0\u043a\u0430\u043b\u044c\u0446\u0438\u044f\u00a0\u0438\u00a0\u0444\u043e\u0441\u0444\u0430\u0442\u043e\u0432\u00a0\u0432\u00a0\u043f\u0438\u0449\u0435);<\/p>\n

\u00b7\u00a0\u0446\u0438\u0442\u043e\u043c\u0435\u0433\u0430\u043b\u0438\u044f\u00a0\u0443\u00a0\u0434\u0435\u0442\u0435\u0439;<\/p>\n

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\u00b7\u00a0\u0438\u043d\u0444\u0430\u0440\u043a\u0442\u00a0\u043b\u0435\u0433\u043a\u043e\u0433\u043e,\u00a0\u043f\u043e\u0447\u043a\u0438;<\/p>\n

\u00b7\u00a0\u0444\u0438\u0437\u0438\u043e\u043b\u043e\u0433\u0438\u0447\u0435\u0441\u043a\u043e\u0435\u00a0(\u0443\u00a0\u043d\u0435\u0434\u043e\u043d\u043e\u0448\u0435\u043d\u043d\u044b\u0445,\u00a0\u0434\u0435\u0442\u0435\u0439\u00a0\u0432\u00a0\u043f\u0435\u0440\u0438\u043e\u0434\u00a0\u0431\u044b\u0441\u0442\u0440\u043e\u0433\u043e\u00a0\u0440\u043e\u0441\u0442\u0430,<\/p>\n

\u0443\u00a0\u0436\u0435\u043d\u0449\u0438\u043d\u00a0\u0432\u00a0\u043f\u043e\u0441\u043b\u0435\u0434\u043d\u0435\u043c\u00a0\u0442\u0440\u0438\u043c\u0435\u0441\u0442\u0440\u0435\u00a0\u0431\u0435\u0440\u0435\u043c\u0435\u043d\u043d\u043e\u0441\u0442\u0438\u00a0\u0438\u00a0\u043f\u043e\u0441\u043b\u0435\u00a0\u043c\u0435\u043d\u043e\u043f\u0430\u0443\u0437\u044b)<\/td>\n

\u00b7\u00a0\u041d\u0430\u0441\u043b\u0435\u0434\u0441\u0442\u0432\u0435\u043d\u043d\u0430\u044f\u00a0\u0433\u0438\u043f\u043e\u0444\u043e\u0441\u0444\u0430\u0442\u0430\u0437\u0435\u043c\u0438\u044f;<\/p>\n

\u00b7\u00a0\u043d\u0430\u0440\u0443\u0448\u0435\u043d\u0438\u044f\u00a0\u0440\u043e\u0441\u0442\u0430\u00a0\u043a\u043e\u0441\u0442\u0438\u00a0(\u0430\u0445\u043e\u043d\u0434\u0440\u043e\u043f\u043b\u0430\u0437\u0438\u044f,\u00a0\u043a\u0440\u0435\u0442\u0438\u043d\u0438\u0437\u043c,<\/p>\n

\u0434\u0435\u0444\u0438\u0446\u0438\u0442\u00a0\u0430\u0441\u043a\u043e\u0440\u0431\u0438\u043d\u043e\u0432\u043e\u0439\u00a0\u043a\u0438\u0441\u043b\u043e\u0442\u044b);<\/p>\n

\u00b7\u00a0\u0433\u0438\u043f\u043e\u0442\u0438\u0440\u0435\u043e\u0437;<\/p>\n

\u00b7\u00a0\u0431\u0435\u043b\u043a\u043e\u0432\u0430\u044f\u00a0\u043d\u0435\u0434\u043e\u0441\u0442\u0430\u0442\u043e\u0447\u043d\u043e\u0441\u0442\u044c\u00a0(\u041a\u0432\u0430\u0448\u0438\u043e\u0440\u043a\u043e\u0440);<\/p>\n

\u00b7\u00a0\u043d\u0435\u0434\u043e\u0441\u0442\u0430\u0442\u043e\u043a\u00a0\u0446\u0438\u043d\u043a\u0430\u00a0\u0438\u00a0\u043c\u0430\u0433\u043d\u0438\u044f\u00a0\u0432\u00a0\u043f\u0438\u0449\u0435<\/td>\n<\/tr>\n<\/tbody>\n<\/table>","protected":false},"featured_media":0,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[953],"product_tag":[],"class_list":{"0":"post-9241","1":"product","2":"type-product","3":"status-publish","5":"product_cat-teste-de-biochimie","7":"first","8":"instock","9":"sold-individually","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/product\/9241","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/comments?post=9241"}],"wp:attachment":[{"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/media?parent=9241"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/product_brand?post=9241"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/product_cat?post=9241"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/product_tag?post=9241"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}