{"id":9236,"date":"2020-04-23T04:32:14","date_gmt":"2020-04-23T01:32:14","guid":{"rendered":"https:\/\/www.synevo.ro\/product\/feritina\/"},"modified":"2026-02-19T01:32:37","modified_gmt":"2026-02-18T23:32:37","slug":"feritina","status":"publish","type":"product","link":"https:\/\/old.synevo.md\/ru\/shop\/feritina\/","title":{"rendered":"\u0424\u0435\u0440\u0440\u0438\u0442\u0438\u043d"},"content":{"rendered":"<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\"><strong><em>Informa\u0163<\/em><\/strong><strong><em>ii generale<\/em><\/strong><\/span><\/p>\n<p style=\"text-align: justify;\">Fierul intracelular este depozitat \u00een doi compu\u015fi, feritin\u0103 \u015fi hemosiderin\u0103. Apoferitina (feritin\u0103 f\u0103r\u0103 fier) are o GM de 440 kD, forma unei sfere goale, cu diametrul de 13 nm, cu o cavitate central\u0103 cu diametrul de 6 nm, unde este depozitat fierul, care comunic\u0103 cu exteriorul prin 6 canale (prin care intr\u0103 \u015fi iese fierul) \u015fi un \u00eenveli\u015f proteic format din 24 molecule, reprezentate de dou\u0103 subunit\u0103\u0163i distincte: H (heavy) \u015fi L (light), cu GM de 21, respectiv 19 kD \u015fi codificate pe cromozomii 11 (H), respectiv 19 (L). O singur\u0103 molecul\u0103 de apoferitin\u0103 poate p\u0103stra ~4500 atomi de fier, GM dep\u0103\u015find \u00een acest caz 800 kD, \u00eens\u0103, de obicei se g\u0103sesc molecule de feritin\u0103 cu cel mult 2000 atomi de fier. Fierul intr\u0103 \u00een molecul\u0103 sub form\u0103 de Fe2+ \u015fi este oxidat sub ac\u0163iunea catalitic\u0103 a apoferitinei (lan\u0163urile H au un centru feroxidazic) \u015fi este p\u0103strat ca polimer trivalent de hidroxid fosfat feric, \u00eenveli\u015ful proteic protej\u00e2nd celula de efectele toxice ale ionilor de fier. Sinteza apoferitinei este stimulat\u0103 de expunerea la fier. Exist\u0103 cel pu\u0163in 20 proteine de isoferitina distincte, cu propor\u0163ii variabile de lan\u0163uri H \u015fi L, care difer\u0103 prin \u00eenc\u0103rc\u0103tura de suprafa\u0163\u0103: isoferitina acid\u0103 con\u0163ine o propor\u0163ie crescut\u0103 de lan\u0163uri H \u015fi predomin\u0103 \u00een \u0163esutul cardiac, renal, placent\u0103, limfocite, monocite, precursorii eritroizi, dar \u015fi \u00een \u0163esuturile tumorale; isoferitina bazic\u0103 este bogat\u0103 \u00een lan\u0163uri L, este mai stabil\u0103 \u015fi se g\u0103se\u015fte \u00een ficat, splin\u0103, precum \u015fi \u00een ser. Feritina se g\u0103se\u015fte \u00een plasm\u0103 \u00een cantit\u0103\u0163i mici \u015fi concentra\u0163ia sa se coreleaz\u0103 cu depozitele de fier. Feritina seric\u0103 este glicozilat\u0103 (suger\u00e2nd secre\u0163ia de c\u0103tre celulele sistemului fagocitic) \u015fi relativ s\u0103rac\u0103 \u00een fier. \u00cen deficitul de fier, feritina scade \u00eenaintea apari\u0163iei anemiei\/altor modific\u0103ri hematologice<sup>1;6<\/sup>.<\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\"><strong><em>Recomand\u0103ri pentru determinarea feritinei<\/em><\/strong><\/span><\/p>\n<div style=\"text-align: justify; padding-left: 30px;\"><span style=\"font-size: 12pt;\">\u2022\u00a0Diagnosticul diferen\u0163ial al anemiilor;<\/span><\/div>\n<div style=\"text-align: justify; padding-left: 30px;\"><span style=\"font-size: 12pt;\">\u2022\u00a0Evaluarea anemiei feriprive \u015fi monitorizarea tratamentului de substitu\u0163ie cu fier (punctul final este reprezentat de umplerea depozitelor de fier) \u015fi a complian\u0163ei la tratament;<\/span><\/div>\n<div style=\"text-align: justify; padding-left: 30px;\"><span style=\"font-size: 12pt;\">\u2022 Monitorizarea categoriilor de pacien\u0163i cu risc de deficit de fier (detectarea deficitului de fier latent): femei \u00eens\u0103rcinate, donatori de sange, copii mici, pacien\u0163i hemodializa\u0163i etc.<\/span><\/div>\n<div style=\"text-align: justify; padding-left: 30px;\"><span style=\"font-size: 12pt;\">\u2022\u00a0Monitorizarea statusului fierului la pacien\u0163i cu boli renale cronice, dializa\u0163i\/nedializa\u0163i.<\/span><\/div>\n<div style=\"text-align: justify; padding-left: 30px;\"><span style=\"font-size: 12pt;\">\u2022\u00a0Diagnosticul \u015fi monitorizarea tratamentului de deple\u0163ie\u00a0\u00een sindroamele de supra\u00eenc\u0103rcare cu fier<sup>5;6<\/sup>.<\/span><\/div>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\"><strong><em>Preg\u0103tire pacient <\/em><\/strong>\u2013 \u00e0 jeun (pe nem\u00e2ncate) sau postprandial (dup\u0103 mas\u0103); evitarea medica\u0163iei radioactive cu 3-4 zile \u00eenaintea test\u0103rii; abstinen\u0163\u0103 de la alcool<sup>3<\/sup>.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\"><strong><em>Specimen recoltat <\/em><\/strong>\u2013 s\u00e2nge venos<sup>7<\/sup>.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\"><strong><em>Recipient de recoltare <\/em><\/strong>\u2013 vacutainer f\u0103r\u0103 anticoagulant cu\/f\u0103r\u0103 gel separator<sup>7<\/sup>.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\"><strong><em>Prelucrare necesar\u0103 dup\u0103 recoltare <\/em><\/strong>\u2013 se separ\u0103 serul prin centrifugare \u015fi se lucreaz\u0103\u00a0\u00een aceea\u015fi zi; dac\u0103 acest lucru nu este posibil, serul se p\u0103streaz\u0103 la 2-8\u00b0C sau la (-20)\u00b0C<sup>7<\/sup>.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\"><strong><em>Volum prob\u0103<\/em><\/strong> \u2013 minim 0.5 mL ser<sup>7<\/sup>.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\"><strong><em>Cauze de respingere a probei <\/em><\/strong>\u2013 specimen intens hemolizat<sup>7<\/sup>.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\"><strong><em>Stabilitate prob\u0103 <\/em><\/strong>\u2013 serul separat este stabil <em>7 zile<\/em> la 2-8\u00b0C; <em>12 luni <\/em>la (-20)\u00b0C<sup>7<\/sup>.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\"><strong><em>Metod\u0103 de determinare <\/em><\/strong>- \u00a0<span style=\"text-decoration: underline;\">imunochimic\u0103 cu detec\u0163ie prin electrochemiluminiscen\u0163\u0103 (ECLIA)<\/span><sup>7<\/sup>.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\"><strong><em>Valori de referin\u0163\u0103 <\/em><\/strong>\u2013 sunt dependente de v\u00e2rst\u0103 \u015fi sex<sup>7<\/sup>.<\/span><\/p>\n<table class=\"wp-block-table w-100\" border=\"1\" cellspacing=\"0\" cellpadding=\"0\">\n<tbody>\n<tr>\n<td valign=\"top\" width=\"332\">\n<p style=\"text-align: center;\"><span style=\"font-size: 10pt;\"><strong><em>V\u00e2rst\u0103 (ani)<\/em><\/strong><strong><em>\u00a0<\/em><\/strong><\/span><\/p>\n<\/td>\n<td valign=\"top\" width=\"328\">\n<p style=\"text-align: center;\"><span style=\"font-size: 10pt;\"><strong><em>Valori (ng\/mL)<\/em><\/strong><\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td valign=\"top\" width=\"332\">\n<p style=\"text-align: center;\"><span style=\"font-size: 10pt;\">&lt;1 an<\/span><\/p>\n<\/td>\n<td valign=\"top\" width=\"328\">\n<p style=\"text-align: center;\"><span style=\"font-size: 10pt;\">12-327<\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td valign=\"top\" width=\"332\">\n<p style=\"text-align: center;\"><span style=\"font-size: 10pt;\">1-3 ani<\/span><\/p>\n<\/td>\n<td valign=\"top\" width=\"328\">\n<p style=\"text-align: center;\"><span style=\"font-size: 10pt;\">6-67<\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td valign=\"top\" width=\"332\">\n<p style=\"text-align: center;\"><span style=\"font-size: 10pt;\">4-6 ani<\/span><\/p>\n<\/td>\n<td valign=\"top\" width=\"328\">\n<p style=\"text-align: center;\"><span style=\"font-size: 10pt;\">4-67<\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td rowspan=\"2\" valign=\"top\" width=\"332\">\n<p style=\"text-align: center;\"><span style=\"font-size: 10pt;\">7-12 ani\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Fete<\/span><\/p>\n<p style=\"text-align: center;\"><span style=\"font-size: 10pt;\">\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0Baie\u0163i<\/span><\/p>\n<\/td>\n<td valign=\"top\" width=\"328\">\n<p style=\"text-align: center;\"><span style=\"font-size: 10pt;\">7-84<\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td valign=\"top\" width=\"328\">\n<p style=\"text-align: center;\"><span style=\"font-size: 10pt;\">14-124<\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td rowspan=\"2\" valign=\"top\" width=\"332\">\n<p style=\"text-align: center;\"><span style=\"font-size: 10pt;\">13-17 ani\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Fete<\/span><\/p>\n<p style=\"text-align: center;\"><span style=\"font-size: 10pt;\">\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0Baie\u0163i<\/span><\/p>\n<\/td>\n<td valign=\"top\" width=\"328\">\n<p style=\"text-align: center;\"><span style=\"font-size: 10pt;\">13-68<\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td valign=\"top\" width=\"328\">\n<p style=\"text-align: center;\"><span style=\"font-size: 10pt;\">14-152<\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td rowspan=\"2\" valign=\"top\" width=\"332\">\n<p style=\"text-align: center;\"><span style=\"font-size: 10pt;\">Adul\u0163i &lt;60 ani\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Femei<\/span><\/p>\n<p style=\"text-align: center;\"><span style=\"font-size: 10pt;\">\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0Barba\u0163i<\/span><\/p>\n<\/td>\n<td valign=\"top\" width=\"328\">\n<p style=\"text-align: center;\"><span style=\"font-size: 10pt;\">13-150<\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td valign=\"top\" width=\"328\">\n<p style=\"text-align: center;\"><span style=\"font-size: 10pt;\">30-400<\/span><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\"><strong><em>Limita de detec\u0163ie<\/em><\/strong> \u2013 0.50 \u00b5g\/L (ng\/mL)<sup>7.<\/sup><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\"><strong><em>Interpretarea rezultatelor\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <\/em><\/strong><\/span><\/p>\n<table class=\"wp-block-table w-100\" border=\"1\" cellspacing=\"0\" cellpadding=\"0\">\n<tbody>\n<tr>\n<td valign=\"top\" width=\"612\">\n<p style=\"text-align: center;\"><span style=\"font-size: 10pt;\"><strong><em>Cre\u015fteri &gt;400 \u00b5g\/L<\/em><\/strong><\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td style=\"text-align: justify;\" valign=\"top\" width=\"612\">\n<p style=\"padding-left: 30px;\"><span style=\"font-size: 10pt;\">\u2022 <em>Supra\u00eenc\u0103rcare cu fier <\/em>\u2013 o feritin\u0103 seric\u0103 normal\u0103 sugereaz\u0103 c\u0103 o supra\u00eenc\u0103rcare cu fier semnificativ\u0103 clinic este pu\u0163in probabil\u0103<sup>6<\/sup>.<\/span><\/p>\n<p style=\"padding-left: 30px;\"><span style=\"font-size: 10pt;\">In hemocromatoza ereditar\u0103 sideremia \u015fi satura\u0163ia transferinei cresc \u00eenaintea feritinei (chiar\u00a0\u00een prezen\u0163a de con\u0163inut crescut de fier la nivel hepatic)<sup>2;5;6<\/sup>. Cre\u015fterea feritinei constituie indica\u0163ie de biopsie hepatic\u0103<sup>2;5<\/sup>.<\/span><\/p>\n<p style=\"padding-left: 30px;\"><span style=\"font-size: 10pt;\">In sindroamele de supra\u00eenc\u0103rcare cu fier secundare (transfuzii, eritropoieza ineficient\u0103, hemodializa\u0163i etc.) feritina este \u00eentotdeauna crescut\u0103<sup>6<\/sup>.<\/span><\/p>\n<p style=\"padding-left: 30px;\"><span style=\"font-size: 10pt;\">\u2022 Boli hepatice parenhimatoase (ciroz\u0103, carcinom hepatocelular), leucemii, limfoame, cancer pancreatic\/bronsic, neuroblastom (exist\u0103 o rela\u0163ie \u00eentre severitatea afect\u0103rii parenhimatoase\/extensia metastazelor \u015fi nivelul feritinei).<\/span><\/p>\n<p style=\"padding-left: 30px;\"><span style=\"font-size: 10pt;\">\u2022 Boli infec\u0163ioase, inflamatorii, tumorale, hipertiroidism<sup>3;5<\/sup>, IMA<sup>5<\/sup> \u2013 f\u0103r\u0103 nici o rela\u0163ie cantitativ\u0103 cu depozitele de fier (reactant de faz\u0103 acut\u0103).<\/span><\/p>\n<p style=\"padding-left: 30px;\"><span style=\"font-size: 10pt;\">\u2022 Anemie megaloblastic\u0103, anemii hemolitice, sideroblastice, talasemie.<\/span><\/p>\n<p style=\"padding-left: 30px;\"><span style=\"font-size: 10pt;\">\u2022 Porfiria cutanea tarda<sup>2;5<\/sup>.<\/span><\/p>\n<p style=\"text-align: justify; padding-left: 30px;\"><span style=\"font-size: 10pt;\"><em>Feritina nu are valoare \u00een evaluarea depozitelor de fier \u00een prezen\u0163a unei afect\u0103ri hepatice parenhimatoase<\/em><sup>3;6<\/sup>.<\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td style=\"text-align: justify;\" valign=\"top\" width=\"612\">\n<p style=\"text-align: center;\"><span style=\"font-size: 10pt;\"><strong><em>Sc\u0103deri<\/em><\/strong><sup>1;5;6;8<\/sup><\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td style=\"text-align: justify;\" valign=\"top\" width=\"612\">\n<p style=\"padding-left: 30px;\"><span style=\"font-size: 10pt;\">De\u015fi nu manifest\u0103 \u00eentotdeauna o rela\u0163ie linear\u0103 cu depozitele de fier, feritina este cel mai bun parametru seric de m\u0103surare a depozitelor de fier. In anemia feripriv\u0103 necomplicat\u0103, feritina este <strong><em>&lt;12\u00b5g\/L<\/em><\/strong><sup>1<\/sup>. C\u00e2nd este prezent\u0103 concomitent o boal\u0103 infec\u0163ioas\u0103\/inflamatorie, feritina seric\u0103 este mai mare, dar \u00een general &lt;50-60 \u00b5g\/L<sup>1<\/sup>. Feritina seric\u0103 sc\u0103zut\u0103 semnific\u0103 \u00eentotdeauna <em>deficit de fier<\/em> (latent\/clinic manifest), dar sensibilitatea testului este sc\u0103zut\u0103, deoarece o valoare normal\u0103 nu exclude deficitul de fier<sup>1<\/sup>.<\/span><\/p>\n<p style=\"padding-left: 30px;\"><span style=\"font-size: 10pt;\">Pentru diferen\u0163ierea anemiei feriprive de anemia din bolile cronice este necesar\u0103 uneori efectuarea de teste suplimentare (receptorii solubili de transferin\u0103 \u2013 TfR, indexul TfR\/feritin\u0103 sau examinarea depozitelor de fier din m\u0103duva osoas\u0103, \u00een special c\u00e2nd sunt prezente ambele forme de anemie)<sup>6<\/sup>.<\/span><\/p>\n<p style=\"padding-left: 30px;\"><span style=\"font-size: 10pt;\">In anemia feripriv\u0103 secundar\u0103 hemoragiei acute, feritina seric\u0103 scade dup\u0103 1-2 s\u0103pt\u0103m\u00e2ni<sup>6<\/sup>.<\/span><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\">\u00a0<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\"><strong><em>Limite \u015fi interferen\u0163e<\/em><\/strong><\/span><\/p>\n<table class=\"wp-block-table w-100\" border=\"1\" cellspacing=\"0\" cellpadding=\"0\">\n<tbody>\n<tr>\n<td valign=\"top\" width=\"396\">\n<p style=\"text-align: center;\"><span style=\"font-size: 10pt;\"><strong><em>Valori crescute<\/em><\/strong><\/span><\/p>\n<\/td>\n<td valign=\"top\" width=\"216\">\n<p style=\"text-align: center;\"><span style=\"font-size: 10pt;\"><strong><em>Valori sc\u0103zute:<\/em><\/strong><\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td valign=\"top\" width=\"396\">\n<p style=\"text-align: center;\"><span style=\"font-size: 10pt;\"><em>\u2022 Varia\u0163ii fiziologice:<\/em> niveluri mai mari la b\u0103rba\u0163i dec\u00e2t la femei; diferen\u0163ele dispar postmenopauz\u0103. Niveluri mai mari la cei care au dieta bogat\u0103\u00a0\u00een carne ro\u015fie dec\u00e2t la vegetarieni<sup>3;5;6<\/sup>.<\/span><\/p>\n<p style=\"text-align: center;\"><span style=\"font-size: 10pt;\"><em>\u2022 <\/em>Hemoliza intens\u0103 a probei de s\u00e2nge (eliberarea feritinei intraeritrocitare)<sup>6<\/sup>.<\/span><\/p>\n<p style=\"text-align: center;\"><span style=\"font-size: 10pt;\"><em>\u2022 <\/em>Alcoolismul<sup>3<\/sup>.<\/span><\/p>\n<p style=\"text-align: center;\"><span style=\"font-size: 10pt;\"><em>\u2022 Medicamente:<\/em> administrarea de preparate de fier i.v. (cre\u015fterea dispropor\u0163ionat\u0103 a feritinei fa\u0163\u0103 de depozitele de fier; rela\u0163ia devine propor\u0163ional\u0103 dup\u0103 2-4 s\u0103pt\u0103m\u00e2ni de la terminarea tratamentului)<sup>6<\/sup> sau p.o., contraceptive orale<sup>4;5<\/sup>, teofilin\u0103<sup>4<\/sup>.<\/span><\/p>\n<\/td>\n<td valign=\"top\" width=\"216\">\n<p style=\"text-align: center;\"><span style=\"font-size: 10pt;\"><em>\u2022 Varia\u0163ii fiziologice:<\/em> niveluri medii u\u015for mai mici la copii<sup>6<\/sup>.<\/span><\/p>\n<p style=\"text-align: center;\"><span style=\"font-size: 10pt;\"><em>\u2022 Medicamente<\/em>: antitiroidiene, acid ascorbic, deferoxamina, metimazol<sup>4<\/sup>.<\/span><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p style=\"text-align: justify;\"><strong><span style=\"font-size: 12pt;\">\u0411\u0438\u0431\u043b\u0438\u043e\u0433\u0440\u0430\u0444\u0438\u044f<\/span><\/strong><\/p>\n<div style=\"text-align: justify;\"><span style=\"font-size: 12pt;\">1. <span style=\"font-size: 10pt;\">Andrews N. Iron Deficiency and Related Disorders. In Wintrobe\u2019s Clinical Hematology. Lippincott Williams &amp; Wilkins, USA, 11 Ed., 2004, 980-1004.<\/span><\/span><\/div>\n<div style=\"text-align: justify;\"><span style=\"font-size: 10pt;\">2. Edwards C. Hemochromatosis. In Wintrobe\u2019s Clinical Hematology. Lippincott Williams &amp; Wilkins, USA, 2 ed. 2004, 1036-1049.<\/span><\/div>\n<div style=\"text-align: justify;\"><span style=\"font-size: 10pt;\">3. Frances Fischbach. Blood Studies: Hematology and Coagulation. In A Manual of Laboratory and Diagnostics Tests. Lippincott Williams &amp; Wilkins, USA, 8 Ed., 2009, 123-125.<\/span><\/div>\n<div style=\"text-align: justify;\"><span style=\"font-size: 10pt;\">4. Frances Fischbach. Effects of the Most Commonly Used Drugs on Frequently Ordered Laboratory Tests. In A Manual of Laboratory and Diagnostic Tests. Lippincott Williams &amp; Wilkins, USA, 8 Ed., 2009, 1238.<\/span><\/div>\n<div style=\"text-align: justify;\"><span style=\"font-size: 10pt;\">5. Jacques Wallach. Afec\u0163iuni hematologice. \u00cen Interpretarea testelor de diagnostic. Editura \u015etiin\u0163elor Medicale, Romania, 7 Ed., 2001, 448-450.<\/span><\/div>\n<div style=\"text-align: justify;\"><span style=\"font-size: 10pt;\">6. Joachim P. Kaltwasser. Ferritin. In Clinical Laboratory Diagnostics-Use and Assessment of Clinical Laboratory Results. Lothar Thomas.TH-Books Verlagsgesellschaft mbH, Germany, 1 Ed., 1998, 278-281.<\/span><\/div>\n<div style=\"text-align: justify;\"><span style=\"font-size: 10pt;\">7. Laborator Synevo. Referin\u0163ele specifice tehnologiei de lucru utilizate. 2010. Ref Type: Catalog.<\/span><\/div>\n<div style=\"text-align: justify;\"><span style=\"font-size: 10pt;\">8. Paul R.Finley, Harold J.Grady, Eugene S. Olsowka. Chemistry. In Laboratory Test Handbook. David S. Jacobs, Wayne R. DeMott, Paul R. Finley et.al., LEXI-COMP Inc., USA, 3 Ed., 1994, 220-222.<\/span><\/div>","protected":false},"excerpt":{"rendered":"<p style=\"text-align: justify;\"><b><i>\u041e\u0431\u0449\u0430\u044f \u0438\u043d\u0444\u043e\u0440\u043c\u0430\u0446\u0438\u044f<\/i><\/b><\/p>\n<p style=\"text-align: justify;\">\u0412\u043d\u0443\u0442\u0440\u0438\u043a\u043b\u0435\u0442\u043e\u0447\u043d\u043e\u0435 \u0436\u0435\u043b\u0435\u0437\u043e \u0445\u0440\u0430\u043d\u0438\u0442\u0441\u044f \u0432 \u0434\u0432\u0443\u0445 \u0441\u043e\u0435\u0434\u0438\u043d\u0435\u043d\u0438\u044f\u0445, \u0444\u0435\u0440\u0440\u0438\u0442\u0438\u043d\u0435 \u0438 \u0433\u0435\u043c\u043e\u0441\u0438\u0434\u0435\u0440\u0438\u043d\u0435. \u0410\u043f\u043e\u0444\u0435\u0440\u0438\u0442\u0438\u043d (\u0444\u0435\u0440\u0440\u0438\u0442\u0438\u043d \u0431\u0435\u0437 \u0436\u0435\u043b\u0435\u0437\u0430) \u0438\u043c\u0435\u0435\u0442 GM 440 \u043a\u0434, \u0444\u043e\u0440\u043c\u0443 \u043f\u043e\u043b\u043e\u0439 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\u0431\u0435\u0434\u0435\u043d \u0436\u0435\u043b\u0435\u0437\u043e\u043c. \u041f\u0440\u0438 \u0434\u0435\u0444\u0438\u0446\u0438\u0442\u0435 \u0436\u0435\u043b\u0435\u0437\u0430 \u0444\u0435\u0440\u0440\u0438\u0442\u0438\u043d \u0443\u043c\u0435\u043d\u044c\u0448\u0430\u0435\u0442\u0441\u044f \u0434\u043e \u043f\u043e\u044f\u0432\u043b\u0435\u043d\u0438\u044f \u0430\u043d\u0435\u043c\u0438\u0438\/\u0434\u0440\u0443\u0433\u0438\u0445 \u0433\u0435\u043c\u0430\u0442\u043e\u043b\u043e\u0433\u0438\u0447\u0435\u0441\u043a\u0438\u0445 \u0438\u0437\u043c\u0435\u043d\u0435\u043d\u0438\u0439 1;6.<\/p>\n<p><strong>\u0420\u0435\u043a\u043e\u043c\u0435\u043d\u0434\u0430\u0446\u0438\u0438 \u043f\u043e \u043e\u043f\u0440\u0435\u0434\u0435\u043b\u0435\u043d\u0438\u044e \u0444\u0435\u0440\u0440\u0438\u0442\u0438\u043d\u0430<\/strong><\/p>\n<ul>\n<li>\u0414\u0438\u0444\u0444\u0435\u0440\u0435\u043d\u0446\u0438\u0430\u043b\u044c\u043d\u0430\u044f \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0430 \u0430\u043d\u0435\u043c\u0438\u0439;<\/li>\n<li>\u041e\u0446\u0435\u043d\u043a\u0430 \u0436\u0435\u043b\u0435\u0437\u043e\u0434\u0435\u0444\u0438\u0446\u0438\u0442\u043d\u043e\u0439 \u0430\u043d\u0435\u043c\u0438\u0438 \u0438 \u043c\u043e\u043d\u0438\u0442\u043e\u0440\u0438\u043d\u0433 \u0437\u0430\u043c\u0435\u0441\u0442\u0438\u0442\u0435\u043b\u044c\u043d\u043e\u0439 \u0442\u0435\u0440\u0430\u043f\u0438\u0438 \u0436\u0435\u043b\u0435\u0437\u043e\u043c (\u043a\u043e\u043d\u0435\u0447\u043d\u0430\u044f \u0442\u043e\u0447\u043a\u0430 \u043f\u0440\u0435\u0434\u0441\u0442\u0430\u0432\u043b\u0435\u043d\u0430 \u0437\u0430\u043f\u043e\u043b\u043d\u0435\u043d\u0438\u0435\u043c \u0437\u0430\u043f\u0430\u0441\u043e\u0432 \u0436\u0435\u043b\u0435\u0437\u0430) \u0438 \u0441\u043e\u043e\u0442\u0432\u0435\u0442\u0441\u0442\u0432\u0438\u044f \u043b\u0435\u0447\u0435\u043d\u0438\u044e;<\/li>\n<li>\u041c\u043e\u043d\u0438\u0442\u043e\u0440\u0438\u043d\u0433 \u043a\u0430\u0442\u0435\u0433\u043e\u0440\u0438\u0439 \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u043e\u0432 \u0441 \u0440\u0438\u0441\u043a\u043e\u043c \u0434\u0435\u0444\u0438\u0446\u0438\u0442\u0430 \u0436\u0435\u043b\u0435\u0437\u0430 (\u043e\u0431\u043d\u0430\u0440\u0443\u0436\u0435\u043d\u0438\u0435 \u043b\u0430\u0442\u0435\u043d\u0442\u043d\u043e\u0433\u043e \u0434\u0435\u0444\u0438\u0446\u0438\u0442\u0430 \u0436\u0435\u043b\u0435\u0437\u0430): \u0431\u0435\u0440\u0435\u043c\u0435\u043d\u043d\u044b\u0435 \u0436\u0435\u043d\u0449\u0438\u043d\u044b, \u0434\u043e\u043d\u043e\u0440\u044b \u043a\u0440\u043e\u0432\u0438, \u043c\u0430\u043b\u0435\u043d\u044c\u043a\u0438\u0435 \u0434\u0435\u0442\u0438, \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u044b \u0441 \u0433\u0435\u043c\u043e\u0434\u0438\u0430\u043b\u0438\u0437\u043e\u043c \u0438 \u0442. \u0434.<\/li>\n<li>\u041c\u043e\u043d\u0438\u0442\u043e\u0440\u0438\u043d\u0433 \u0441\u043e\u0441\u0442\u043e\u044f\u043d\u0438\u044f \u0436\u0435\u043b\u0435\u0437\u0430 \u0443 \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u043e\u0432 \u0441 \u0445\u0440\u043e\u043d\u0438\u0447\u0435\u0441\u043a\u0438\u043c \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0435\u043c \u043f\u043e\u0447\u0435\u043a, \u0434\u0438\u0430\u043b\u0438\u0437\u043e\u043c \/ \u043d\u0435\u0434\u0438\u0430\u043b\u0438\u0437\u043e\u043c.<\/li>\n<li>\u0414\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0430 \u0438 \u043c\u043e\u043d\u0438\u0442\u043e\u0440\u0438\u043d\u0433 \u043b\u0435\u0447\u0435\u043d\u0438\u044f \u0438\u0441\u0442\u043e\u0449\u0435\u043d\u0438\u044f \u043f\u0440\u0438 \u0441\u0438\u043d\u0434\u0440\u043e\u043c\u0430\u0445 \u043f\u0435\u0440\u0435\u0433\u0440\u0443\u0437\u043a\u0438 \u0436\u0435\u043b\u0435\u0437\u043e\u043c5;6.<\/li>\n<\/ul>\n<p><strong>\u041f\u043e\u0434\u0433\u043e\u0442\u043e\u0432\u043a\u0430 \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u0430<\/strong> \u2013 \u043d\u0430\u0442\u043e\u0449\u0430\u043a (\u043d\u0430 \u043d\u0435\u0441\u044a\u0435\u0434\u0435\u043d\u043d\u043e\u043c) \u0438\u043b\u0438 \u043f\u043e\u0441\u0442\u043f\u0440\u0430\u043d\u0434\u0438\u0430\u043b\u044c\u043d\u043e\u043c (\u043f\u043e\u0441\u043b\u0435 \u0435\u0434\u044b); \u0438\u0437\u0431\u0435\u0433\u0430\u0442\u044c \u0440\u0430\u0434\u0438\u043e\u0430\u043a\u0442\u0438\u0432\u043d\u044b\u0445 \u043b\u0435\u043a\u0430\u0440\u0441\u0442\u0432 \u0437\u0430 3-4 \u0434\u043d\u044f \u0434\u043e \u0442\u0435\u0441\u0442\u0438\u0440\u043e\u0432\u0430\u043d\u0438\u044f; \u0432\u043e\u0437\u0434\u0435\u0440\u0436\u0430\u043d\u0438\u0435 \u043e\u0442 \u0430\u043b\u043a\u043e\u0433\u043e\u043b\u044f3.<\/p>\n<p><strong>\u0421\u043e\u0431\u0440\u0430\u043d\u043d\u044b\u0439 \u043e\u0431\u0440\u0430\u0437\u0435\u0446<\/strong>-\u0432\u0435\u043d\u043e\u0437\u043d\u0430\u044f \u043a\u0440\u043e\u0432\u044c 7.<\/p>\n<p><strong>\u041a\u043e\u043d\u0442\u0435\u0439\u043d\u0435\u0440 \u0434\u043b\u044f \u0441\u0431\u043e\u0440\u0430<\/strong>-vacutainer \u0431\u0435\u0437 \u0430\u043d\u0442\u0438\u043a\u043e\u0430\u0433\u0443\u043b\u044f\u043d\u0442\u0430 \u0441 \/ \u0431\u0435\u0437 \u0441\u0435\u043f\u0430\u0440\u0430\u0442\u043e\u0440\u043d\u043e\u0433\u043e \u0433\u0435\u043b\u044f 7.<\/p>\n<p><strong>\u041d\u0435\u043e\u0431\u0445\u043e\u0434\u0438\u043c\u0430\u044f \u043e\u0431\u0440\u0430\u0431\u043e\u0442\u043a\u0430 \u043f\u043e\u0441\u043b\u0435 \u0441\u0431\u043e\u0440\u0430<\/strong> &#8211; \u043e\u0442\u0434\u0435\u043b\u044f\u044e\u0442 \u0441\u044b\u0432\u043e\u0440\u043e\u0442\u043a\u0443 \u0446\u0435\u043d\u0442\u0440\u0438\u0444\u0443\u0433\u0438\u0440\u043e\u0432\u0430\u043d\u0438\u0435\u043c \u0438 \u043e\u0431\u0440\u0430\u0431\u0430\u0442\u044b\u0432\u0430\u044e\u0442 \u0432 \u0442\u043e\u0442 \u0436\u0435 \u0434\u0435\u043d\u044c; \u0435\u0441\u043b\u0438 \u044d\u0442\u043e \u043d\u0435\u0432\u043e\u0437\u043c\u043e\u0436\u043d\u043e, \u0441\u044b\u0432\u043e\u0440\u043e\u0442\u043a\u0443 \u0445\u0440\u0430\u043d\u044f\u0442 \u043f\u0440\u0438 2-8\u00b0C \u0438\u043b\u0438 (-20)\u00b0C7.<\/p>\n<p><strong>\u041e\u0431\u044a\u0435\u043c \u043e\u0431\u0440\u0430\u0437\u0446\u0430<\/strong>-\u043c\u0438\u043d\u0438\u043c\u0443\u043c 0.5 \u043c\u043b ser7.<\/p>\n<p><strong>\u041f\u0440\u0438\u0447\u0438\u043d\u044b \u043e\u0442\u0442\u043e\u0440\u0436\u0435\u043d\u0438\u044f \u043e\u0431\u0440\u0430\u0437\u0446\u0430<\/strong>-\u0438\u043d\u0442\u0435\u043d\u0441\u0438\u0432\u043d\u044b\u0439 \u0433\u0435\u043c\u043e\u043b\u0438\u0437\u0438\u0440\u043e\u0432\u0430\u043d\u043d\u044b\u0439 \u043e\u0431\u0440\u0430\u0437\u0435\u0446 7.<\/p>\n<p><strong>\u0421\u0442\u0430\u0431\u0438\u043b\u044c\u043d\u043e\u0441\u0442\u044c \u043e\u0431\u0440\u0430\u0437\u0446\u0430<\/strong>-\u043e\u0442\u0434\u0435\u043b\u044c\u043d\u0430\u044f \u0441\u044b\u0432\u043e\u0440\u043e\u0442\u043a\u0430 \u0441\u0442\u0430\u0431\u0438\u043b\u044c\u043d\u0430 7 \u0434\u043d\u0435\u0439 \u043f\u0440\u0438 2-8\u00b0c; 12 \u043c\u0435\u0441\u044f\u0446\u0435\u0432 \u043f\u0440\u0438 (-20)\u00b0C7.<\/p>\n<p><strong>\u041c\u0435\u0442\u043e\u0434 \u043e\u043f\u0440\u0435\u0434\u0435\u043b\u0435\u043d\u0438\u044f<\/strong>-\u0438\u043c\u043c\u0443\u043d\u043e\u0445\u0438\u043c\u0438\u0447\u0435\u0441\u043a\u0438\u0439 \u0441 \u044d\u043b\u0435\u043a\u0442\u0440\u043e\u0445\u0435\u043c\u0438\u043b\u044e\u043c\u0438\u043d\u0435\u0441\u0446\u0435\u043d\u0442\u043d\u044b\u043c \u043e\u0431\u043d\u0430\u0440\u0443\u0436\u0435\u043d\u0438\u0435\u043c (ECLIA)7.<\/p>\n<p><strong>\u041a\u043e\u043d\u0442\u0440\u043e\u043b\u044c\u043d\u044b\u0435 \u0437\u043d\u0430\u0447\u0435\u043d\u0438\u044f<\/strong>-\u0437\u0430\u0432\u0438\u0441\u044f\u0442 \u043e\u0442 \u0432\u043e\u0437\u0440\u0430\u0441\u0442\u0430 \u0438 \u043f\u043e\u043b\u0430.<\/p>\n<table class=\"wp-block-table w-100\" border=\"1\" cellspacing=\"0\" cellpadding=\"0\">\n<tbody>\n<tr>\n<td valign=\"top\" width=\"332\">\n<p style=\"text-align: center;\"><span style=\"font-size: 10pt;\"><strong><em>\u0412\u043e\u0437\u0440\u0430\u0441\u0442(\u0433\u043e\u0434\u0430)<\/em><\/strong><\/span><\/p>\n<\/td>\n<td valign=\"top\" width=\"328\">\n<p style=\"text-align: center;\"><span style=\"font-size: 10pt;\"><strong><em>\u041e\u0431\u044a\u0435\u043c (ng\/mL)<\/em><\/strong><\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td valign=\"top\" width=\"332\">\n<p style=\"text-align: center;\"><span style=\"font-size: 10pt;\">&lt;1 \u0433\u043e\u0434<\/span><\/p>\n<\/td>\n<td valign=\"top\" width=\"328\">\n<p style=\"text-align: center;\"><span style=\"font-size: 10pt;\">12-327<\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td valign=\"top\" width=\"332\">\n<p style=\"text-align: center;\"><span style=\"font-size: 10pt;\">1-3 \u0433\u043e\u0434\u0430<\/span><\/p>\n<\/td>\n<td valign=\"top\" width=\"328\">\n<p style=\"text-align: center;\"><span style=\"font-size: 10pt;\">6-67<\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td valign=\"top\" width=\"332\">\n<p style=\"text-align: center;\"><span style=\"font-size: 10pt;\">4-6 \u043b\u0435\u0442<\/span><\/p>\n<\/td>\n<td valign=\"top\" width=\"328\">\n<p style=\"text-align: center;\"><span style=\"font-size: 10pt;\">4-67<\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td rowspan=\"2\" valign=\"top\" width=\"332\">\n<p style=\"text-align: center;\"><span style=\"font-size: 10pt;\">7-12 \u043b\u0435\u0442\u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0\u0414\u0435\u0432\u043e\u0447\u043a\u0438<\/span><\/p>\n<p style=\"text-align: center;\"><span style=\"font-size: 10pt;\">\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u041c\u0430\u043b\u044c\u0447\u0438\u043a\u0438<\/span><\/p>\n<\/td>\n<td valign=\"top\" width=\"328\">\n<p style=\"text-align: center;\"><span style=\"font-size: 10pt;\">7-84<\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td valign=\"top\" width=\"328\">\n<p style=\"text-align: center;\"><span style=\"font-size: 10pt;\">14-124<\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td rowspan=\"2\" valign=\"top\" width=\"332\">\n<p style=\"text-align: center;\"><span style=\"font-size: 10pt;\">13-17 \u043b\u0435\u0442\u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0\u0414\u0435\u0432\u043e\u0447\u043a\u0438<\/span><\/p>\n<p style=\"text-align: center;\"><span style=\"font-size: 10pt;\">\u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0\u041c\u0430\u043b\u044c\u0447\u0438\u043a\u0438<\/span><\/p>\n<\/td>\n<td valign=\"top\" width=\"328\">\n<p style=\"text-align: center;\"><span style=\"font-size: 10pt;\">13-68<\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td valign=\"top\" width=\"328\">\n<p style=\"text-align: center;\"><span style=\"font-size: 10pt;\">14-152<\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td rowspan=\"2\" valign=\"top\" width=\"332\">\n<p style=\"text-align: center;\"><span style=\"font-size: 10pt;\">\u0412\u0437\u0440\u043e\u0441\u043b\u044b\u0435 &lt;60 \u043b\u0435\u0442\u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u0416\u0435\u043d\u0449\u0438\u043d\u044b<\/span><\/p>\n<p style=\"text-align: center;\"><span style=\"font-size: 10pt;\">\u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u041c\u0443\u0436\u0447\u0438\u043d\u044b<\/span><\/p>\n<\/td>\n<td valign=\"top\" width=\"328\">\n<p style=\"text-align: center;\"><span style=\"font-size: 10pt;\">13-150<\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td valign=\"top\" width=\"328\">\n<p style=\"text-align: center;\"><span style=\"font-size: 10pt;\">30-400<\/span><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\"><strong>\u041f\u0440\u0435\u0434\u0435\u043b \u043e\u0431\u043d\u0430\u0440\u0443\u0436\u0435\u043d\u0438\u044f<\/strong> \u2013 0.50 \u00b5g\/L (ng\/mL)<sup>7.<\/sup><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\"><strong><em>\u0418\u043d\u0442\u0435\u0440\u043f\u0440\u0435\u0442\u0430\u0446\u0438\u044f \u0430\u043d\u0430\u043b\u0438\u0437\u043e\u0432\u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0<\/em><\/strong><\/span><\/p>\n<table class=\"wp-block-table w-100\" border=\"1\" cellspacing=\"0\" cellpadding=\"0\">\n<tbody>\n<tr>\n<td valign=\"top\" width=\"612\">\n<p style=\"text-align: center;\"><span style=\"font-size: 10pt;\"><strong><em>\u0423\u0432\u0435\u043b\u0438\u0447\u0435\u043d\u0438\u0435 &gt;400 \u00b5g\/L<\/em><\/strong><\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td style=\"text-align: justify;\" valign=\"top\" width=\"612\">\n<p style=\"padding-left: 30px;\"><span style=\"font-size: 10pt;\">\u2022 <\/span>\u041f\u0435\u0440\u0435\u0433\u0440\u0443\u0437\u043a\u0430 \u0436\u0435\u043b\u0435\u0437\u043e\u043c &#8211; \u043d\u043e\u0440\u043c\u0430\u043b\u044c\u043d\u044b\u0439 \u0441\u044b\u0432\u043e\u0440\u043e\u0442\u043e\u0447\u043d\u044b\u0439 \u0444\u0435\u0440\u0440\u0438\u0442\u0438\u043d \u043f\u0440\u0435\u0434\u043f\u043e\u043b\u0430\u0433\u0430\u0435\u0442, \u0447\u0442\u043e \u043a\u043b\u0438\u043d\u0438\u0447\u0435\u0441\u043a\u0438 \u0437\u043d\u0430\u0447\u0438\u043c\u0430\u044f \u043f\u0435\u0440\u0435\u0433\u0440\u0443\u0437\u043a\u0430 \u0436\u0435\u043b\u0435\u0437\u043e\u043c \u043c\u0430\u043b\u043e\u0432\u0435\u0440\u043e\u044f\u0442\u043d\u04306.<\/p>\n<p style=\"padding-left: 30px;\">\u041f\u0440\u0438 \u043d\u0430\u0441\u043b\u0435\u0434\u0441\u0442\u0432\u0435\u043d\u043d\u043e\u043c \u0433\u0435\u043c\u043e\u0445\u0440\u043e\u043c\u0430\u0442\u043e\u0437\u0435 \u0441\u0438\u0434\u0435\u0440\u0435\u043c\u0438\u044f \u0438 \u043d\u0430\u0441\u044b\u0449\u0435\u043d\u0438\u0435 \u0442\u0440\u0430\u043d\u0441\u0444\u0435\u0440\u0440\u0438\u043d\u0430 \u0443\u0432\u0435\u043b\u0438\u0447\u0438\u0432\u0430\u044e\u0442\u0441\u044f \u0434\u043e \u0444\u0435\u0440\u0440\u0438\u0442\u0438\u043d\u0430 (\u0434\u0430\u0436\u0435 \u043f\u0440\u0438 \u043d\u0430\u043b\u0438\u0447\u0438\u0438 \u043f\u043e\u0432\u044b\u0448\u0435\u043d\u043d\u043e\u0433\u043e \u0441\u043e\u0434\u0435\u0440\u0436\u0430\u043d\u0438\u044f \u0436\u0435\u043b\u0435\u0437\u0430 \u0432 \u043f\u0435\u0447\u0435\u043d\u0438)2; 5; 6. \u041f\u043e\u0432\u044b\u0448\u0435\u043d\u0438\u0435 \u0443\u0440\u043e\u0432\u043d\u044f \u0444\u0435\u0440\u0440\u0438\u0442\u0438\u043d\u0430 \u044f\u0432\u043b\u044f\u0435\u0442\u0441\u044f \u043f\u043e\u043a\u0430\u0437\u0430\u043d\u0438\u0435\u043c \u043a \u0431\u0438\u043e\u043f\u0441\u0438\u0438 \u043f\u0435\u0447\u0435\u043d\u0438 2;5.<\/p>\n<p style=\"padding-left: 30px;\">\u041f\u0440\u0438 \u0441\u0438\u043d\u0434\u0440\u043e\u043c\u0430\u0445 \u0432\u0442\u043e\u0440\u0438\u0447\u043d\u043e\u0439 \u043f\u0435\u0440\u0435\u0433\u0440\u0443\u0437\u043a\u0438 \u0436\u0435\u043b\u0435\u0437\u043e\u043c (\u043f\u0435\u0440\u0435\u043b\u0438\u0432\u0430\u043d\u0438\u0435 \u043a\u0440\u043e\u0432\u0438, \u043d\u0435\u044d\u0444\u0444\u0435\u043a\u0442\u0438\u0432\u043d\u044b\u0439 \u044d\u0440\u0438\u0442\u0440\u043e\u043f\u043e\u044d\u0437, \u0433\u0435\u043c\u043e\u0434\u0438\u0430\u043b\u0438\u0437 \u0438 \u0442. \u0434.) \u0444\u0435\u0440\u0440\u0438\u0442\u0438\u043d \u0432\u0441\u0435\u0433\u0434\u0430 \u043f\u043e\u0432\u044b\u0448\u0435\u043d6.<\/p>\n<p style=\"padding-left: 30px;\">* \u041f\u0430\u0440\u0435\u043d\u0445\u0438\u043c\u0430\u0442\u043e\u0437\u043d\u044b\u0435 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u044f \u043f\u0435\u0447\u0435\u043d\u0438 \u2022 \u0446\u0438\u0440\u0440\u043e\u0437, \u0433\u0435\u043f\u0430\u0442\u043e\u0446\u0435\u043b\u043b\u044e\u043b\u044f\u0440\u043d\u0430\u044f \u043a\u0430\u0440\u0446\u0438\u043d\u043e\u043c\u0430), \u043b\u0435\u0439\u043a\u0435\u043c\u0438\u0438, \u043b\u0438\u043c\u0444\u043e\u043c\u044b, \u0440\u0430\u043a \u043f\u043e\u0434\u0436\u0435\u043b\u0443\u0434\u043e\u0447\u043d\u043e\u0439 \u0436\u0435\u043b\u0435\u0437\u044b\/\u0431\u0440\u043e\u043d\u0445\u043e\u0432, \u043d\u0435\u0439\u0440\u043e\u0431\u043b\u0430\u0441\u0442\u043e\u043c\u0430 (\u0441\u0443\u0449\u0435\u0441\u0442\u0432\u0443\u0435\u0442 \u0441\u0432\u044f\u0437\u044c \u043c\u0435\u0436\u0434\u0443 \u0442\u044f\u0436\u0435\u0441\u0442\u044c\u044e \u043f\u0430\u0440\u0435\u043d\u0445\u0438\u043c\u0430\u0442\u043e\u0437\u043d\u043e\u0433\u043e \u043f\u043e\u0432\u0440\u0435\u0436\u0434\u0435\u043d\u0438\u044f\/\u0440\u0430\u0441\u0448\u0438\u0440\u0435\u043d\u0438\u0435\u043c \u043c\u0435\u0442\u0430\u0441\u0442\u0430\u0437\u043e\u0432 \u0438 \u0443\u0440\u043e\u0432\u043d\u0435\u043c \u0444\u0435\u0440\u0440\u0438\u0442\u0438\u043d\u0430).<\/p>\n<p style=\"padding-left: 30px;\">* \u0418\u043d\u0444\u0435\u043a\u0446\u0438\u043e\u043d\u043d\u044b\u0435, \u0432\u043e\u0441\u043f\u0430\u043b\u0438\u0442\u0435\u043b\u044c\u043d\u044b\u0435, \u043e\u043f\u0443\u0445\u043e\u043b\u0435\u0432\u044b\u0435 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u044f, \u0433\u0438\u043f\u0435\u0440\u0442\u0438\u0440\u0435\u043e\u04373; 5, IMA5 &#8211; \u0431\u0435\u0437 \u043a\u043e\u043b\u0438\u0447\u0435\u0441\u0442\u0432\u0435\u043d\u043d\u043e\u0439 \u0441\u0432\u044f\u0437\u0438 \u0441 \u043e\u0442\u043b\u043e\u0436\u0435\u043d\u0438\u044f\u043c\u0438 \u0436\u0435\u043b\u0435\u0437\u0430 (\u0440\u0435\u0430\u0433\u0435\u043d\u0442 \u043e\u0441\u0442\u0440\u043e\u0439 \u0444\u0430\u0437\u044b).<\/p>\n<p style=\"padding-left: 30px;\">* \u041c\u0435\u0433\u0430\u043b\u043e\u0431\u043b\u0430\u0441\u0442\u043d\u0430\u044f \u0430\u043d\u0435\u043c\u0438\u044f, \u0433\u0435\u043c\u043e\u043b\u0438\u0442\u0438\u0447\u0435\u0441\u043a\u0438\u0435 \u0430\u043d\u0435\u043c\u0438\u0438, \u0441\u0438\u0434\u0435\u0440\u043e\u0431\u043b\u0430\u0441\u0442\u044b, \u0442\u0430\u043b\u0430\u0441\u0441\u0435\u043c\u0438\u044f.<\/p>\n<p style=\"padding-left: 30px;\">* \u041f\u043e\u0437\u0434\u043d\u044f\u044f \u043a\u043e\u0436\u043d\u0430\u044f \u041f\u043e\u0440\u0444\u0438\u0440\u0438\u044f 2;5.<\/p>\n<p style=\"padding-left: 30px;\">\u0424\u0435\u0440\u0440\u0438\u0442\u0438\u043d \u0431\u0435\u0441\u043f\u043e\u043b\u0435\u0437\u0435\u043d \u043f\u0440\u0438 \u043e\u0446\u0435\u043d\u043a\u0435 \u0437\u0430\u043f\u0430\u0441\u043e\u0432 \u0436\u0435\u043b\u0435\u0437\u0430 \u043f\u0440\u0438 \u043d\u0430\u043b\u0438\u0447\u0438\u0438 \u043f\u0430\u0440\u0435\u043d\u0445\u0438\u043c\u0430\u0442\u043e\u0437\u043d\u043e\u0433\u043e \u043f\u043e\u0432\u0440\u0435\u0436\u0434\u0435\u043d\u0438\u044f \u043f\u0435\u0447\u0435\u043d\u0438<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td style=\"text-align: justify;\" valign=\"top\" width=\"612\">\n<p style=\"text-align: center;\"><span style=\"font-size: 10pt;\"><strong><em>\u0421\u043d\u0438\u0436\u0435\u043d\u0438\u0435<\/em><\/strong><sup>1;5;6;8<\/sup><\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td style=\"text-align: justify;\" valign=\"top\" width=\"612\">\u0425\u043e\u0442\u044f \u0444\u0435\u0440\u0440\u0438\u0442\u0438\u043d \u043d\u0435 \u0432\u0441\u0435\u0433\u0434\u0430 \u043f\u0440\u043e\u044f\u0432\u043b\u044f\u0435\u0442 \u043b\u0438\u043d\u0435\u0439\u043d\u0443\u044e \u0441\u0432\u044f\u0437\u044c \u0441 \u043e\u0442\u043b\u043e\u0436\u0435\u043d\u0438\u044f\u043c\u0438 \u0436\u0435\u043b\u0435\u0437\u0430, \u043e\u043d \u044f\u0432\u043b\u044f\u0435\u0442\u0441\u044f \u043b\u0443\u0447\u0448\u0438\u043c \u043f\u0430\u0440\u0430\u043c\u0435\u0442\u0440\u043e\u043c \u0438\u0437\u043c\u0435\u0440\u0435\u043d\u0438\u044f \u0437\u0430\u043f\u0430\u0441\u043e\u0432 \u0436\u0435\u043b\u0435\u0437\u0430 \u0432 \u0441\u044b\u0432\u043e\u0440\u043e\u0442\u043a\u0435. \u041f\u0440\u0438 \u043d\u0435\u043e\u0441\u043b\u043e\u0436\u043d\u0435\u043d\u043d\u043e\u0439 \u0436\u0435\u043b\u0435\u0437\u043e\u0434\u0435\u0444\u0438\u0446\u0438\u0442\u043d\u043e\u0439 \u0430\u043d\u0435\u043c\u0438\u0438 \u0444\u0435\u0440\u0440\u0438\u0442\u0438\u043d \u0441\u043e\u0441\u0442\u0430\u0432\u043b\u044f\u0435\u0442 &lt;12 \u043c\u043a\u0433 \/ \u041b1. \u041f\u0440\u0438 \u0441\u043e\u043f\u0443\u0442\u0441\u0442\u0432\u0443\u044e\u0449\u0435\u043c \u0438\u043d\u0444\u0435\u043a\u0446\u0438\u043e\u043d\u043d\u043e\u043c\/\u0432\u043e\u0441\u043f\u0430\u043b\u0438\u0442\u0435\u043b\u044c\u043d\u043e\u043c \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0438 \u0441\u044b\u0432\u043e\u0440\u043e\u0442\u043e\u0447\u043d\u044b\u0439 \u0444\u0435\u0440\u0440\u0438\u0442\u0438\u043d \u0432\u044b\u0448\u0435, \u043d\u043e \u043e\u0431\u044b\u0447\u043d\u043e &lt;50-60 \u043c\u043a\u0433\/\u041b1. \u041d\u0438\u0437\u043a\u0438\u0439 \u0443\u0440\u043e\u0432\u0435\u043d\u044c \u0444\u0435\u0440\u0440\u0438\u0442\u0438\u043d\u0430 \u0432 \u0441\u044b\u0432\u043e\u0440\u043e\u0442\u043a\u0435 \u0432\u0441\u0435\u0433\u0434\u0430 \u043e\u0437\u043d\u0430\u0447\u0430\u0435\u0442 \u0434\u0435\u0444\u0438\u0446\u0438\u0442 \u0436\u0435\u043b\u0435\u0437\u0430 (\u043b\u0430\u0442\u0435\u043d\u0442\u043d\u044b\u0439\/\u043a\u043b\u0438\u043d\u0438\u0447\u0435\u0441\u043a\u0438 \u043f\u0440\u043e\u044f\u0432\u043b\u0435\u043d\u043d\u044b\u0439), \u043d\u043e \u0447\u0443\u0432\u0441\u0442\u0432\u0438\u0442\u0435\u043b\u044c\u043d\u043e\u0441\u0442\u044c \u0442\u0435\u0441\u0442\u0430 \u043d\u0438\u0437\u043a\u0430\u044f, \u043f\u043e\u0441\u043a\u043e\u043b\u044c\u043a\u0443 \u043d\u043e\u0440\u043c\u0430\u043b\u044c\u043d\u043e\u0435 \u0437\u043d\u0430\u0447\u0435\u043d\u0438\u0435 \u043d\u0435 \u0438\u0441\u043a\u043b\u044e\u0447\u0430\u0435\u0442 \u0434\u0435\u0444\u0438\u0446\u0438\u0442\u0430 \u0436\u0435\u043b\u0435\u0437\u04301.<\/p>\n<p>\u0414\u043b\u044f \u0434\u0438\u0444\u0444\u0435\u0440\u0435\u043d\u0446\u0438\u0430\u0446\u0438\u0438 \u0436\u0435\u043b\u0435\u0437\u043e\u0434\u0435\u0444\u0438\u0446\u0438\u0442\u043d\u043e\u0439 \u0430\u043d\u0435\u043c\u0438\u0438 \u043e\u0442 \u0445\u0440\u043e\u043d\u0438\u0447\u0435\u0441\u043a\u0438\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439 \u0438\u043d\u043e\u0433\u0434\u0430 \u043d\u0435\u043e\u0431\u0445\u043e\u0434\u0438\u043c\u043e \u043f\u0440\u043e\u0432\u0435\u0441\u0442\u0438 \u0434\u043e\u043f\u043e\u043b\u043d\u0438\u0442\u0435\u043b\u044c\u043d\u043e\u0435 \u0442\u0435\u0441\u0442\u0438\u0440\u043e\u0432\u0430\u043d\u0438\u0435 (\u0440\u0430\u0441\u0442\u0432\u043e\u0440\u0438\u043c\u044b\u0435 \u0440\u0435\u0446\u0435\u043f\u0442\u043e\u0440\u044b \u0442\u0440\u0430\u043d\u0441\u0444\u0435\u0440\u0440\u0438\u043d\u0430 \u2013 TfR, \u0438\u043d\u0434\u0435\u043a\u0441 TfR\/\u0444\u0435\u0440\u0440\u0438\u0442\u0438\u043d\u0430 \u0438\u043b\u0438 \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u0435 \u0437\u0430\u043f\u0430\u0441\u043e\u0432 \u0436\u0435\u043b\u0435\u0437\u0430 \u0432 \u043a\u043e\u0441\u0442\u043d\u043e\u043c \u043c\u043e\u0437\u0433\u0435, \u043e\u0441\u043e\u0431\u0435\u043d\u043d\u043e \u043f\u0440\u0438 \u043d\u0430\u043b\u0438\u0447\u0438\u0438 \u043e\u0431\u0435\u0438\u0445 \u0444\u043e\u0440\u043c \u0430\u043d\u0435\u043c\u0438\u0438)6.<\/p>\n<p>\u041f\u0440\u0438 \u0436\u0435\u043b\u0435\u0437\u043e\u0434\u0435\u0444\u0438\u0446\u0438\u0442\u043d\u043e\u0439 \u0430\u043d\u0435\u043c\u0438\u0438, \u0432\u0442\u043e\u0440\u0438\u0447\u043d\u043e\u0439 \u043f\u043e \u043e\u0442\u043d\u043e\u0448\u0435\u043d\u0438\u044e \u043a \u043e\u0441\u0442\u0440\u043e\u043c\u0443 \u043a\u0440\u043e\u0432\u043e\u0438\u0437\u043b\u0438\u044f\u043d\u0438\u044e, \u0444\u0435\u0440\u0440\u0438\u0442\u0438\u043d \u0441\u044b\u0432\u043e\u0440\u043e\u0442\u043a\u0438 \u0441\u043d\u0438\u0436\u0430\u0435\u0442\u0441\u044f \u0447\u0435\u0440\u0435\u0437 1-2 \u043d\u0435\u0434\u0435\u043b\u0438 6.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p style=\"text-align: justify;\"><span style=\"font-size: 12pt;\">\u00a0<\/span><\/p>\n<p style=\"text-align: justify;\"><strong>\u0413\u0440\u0430\u043d\u0438\u0446\u044b \u0438 \u043f\u043e\u043c\u0435\u0445\u0438<\/strong><\/p>\n<table class=\"wp-block-table w-100\" border=\"1\" cellspacing=\"0\" cellpadding=\"0\">\n<tbody>\n<tr>\n<td valign=\"top\" width=\"396\">\n<p style=\"text-align: center;\"><strong>\u041f\u043e\u0432\u044b\u0448\u0435\u043d\u043d\u044b\u0435 \u0437\u043d\u0430\u0447\u0435\u043d\u0438\u044f<\/strong><\/p>\n<\/td>\n<td valign=\"top\" width=\"216\">\n<p style=\"text-align: center;\"><span style=\"font-size: 10pt;\"><strong><em>\u041f\u043e\u043d\u0438\u0436\u0435\u043d\u043d\u044b\u0435 \u0437\u043d\u0430\u0447\u0435\u043d\u0438\u044f<\/em><\/strong><\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td valign=\"top\" width=\"396\">* \u0424\u0438\u0437\u0438\u043e\u043b\u043e\u0433\u0438\u0447\u0435\u0441\u043a\u0438\u0435 \u0432\u0430\u0440\u0438\u0430\u0446\u0438\u0438: \u0431\u043e\u043b\u0435\u0435 \u0432\u044b\u0441\u043e\u043a\u0438\u0435 \u0443\u0440\u043e\u0432\u043d\u0438 \u0443 \u043c\u0443\u0436\u0447\u0438\u043d, \u0447\u0435\u043c \u0443 \u0436\u0435\u043d\u0449\u0438\u043d; \u0440\u0430\u0437\u043b\u0438\u0447\u0438\u044f \u0438\u0441\u0447\u0435\u0437\u0430\u044e\u0442 \u0432 \u043f\u043e\u0441\u0442\u043c\u0435\u043d\u043e\u043f\u0430\u0443\u0437\u0435. \u0411\u043e\u043b\u0435\u0435 \u0432\u044b\u0441\u043e\u043a\u0438\u0435 \u0443\u0440\u043e\u0432\u043d\u0438 \u0443 \u0442\u0435\u0445, \u043a\u0442\u043e \u043f\u0440\u0438\u0434\u0435\u0440\u0436\u0438\u0432\u0430\u0435\u0442\u0441\u044f \u0434\u0438\u0435\u0442\u044b \u0441 \u0432\u044b\u0441\u043e\u043a\u0438\u043c \u0441\u043e\u0434\u0435\u0440\u0436\u0430\u043d\u0438\u0435\u043c \u043a\u0440\u0430\u0441\u043d\u043e\u0433\u043e \u043c\u044f\u0441\u0430, \u0447\u0435\u043c \u0443 \u0432\u0435\u0433\u0435\u0442\u0430\u0440\u0438\u0430\u043d\u0446\u0435\u04323; 5; 6.<\/p>\n<p>* \u0418\u043d\u0442\u0435\u043d\u0441\u0438\u0432\u043d\u044b\u0439 \u0433\u0435\u043c\u043e\u043b\u0438\u0437 \u043e\u0431\u0440\u0430\u0437\u0446\u0430 \u043a\u0440\u043e\u0432\u0438 (\u0432\u044b\u0441\u0432\u043e\u0431\u043e\u0436\u0434\u0435\u043d\u0438\u0435 \u0432\u043d\u0443\u0442\u0440\u0438\u044d\u0440\u0438\u0442\u0440\u043e\u0446\u0438\u0442\u0430\u0440\u043d\u043e\u0433\u043e \u0444\u0435\u0440\u0440\u0438\u0442\u0438\u043d\u0430)6.<\/p>\n<p>* \u0410\u043b\u043a\u043e\u0433\u043e\u043b\u0438\u0437\u043c 3.<\/p>\n<p>* \u041b\u0435\u043a\u0430\u0440\u0441\u0442\u0432\u0430: \u0432\u0432\u0435\u0434\u0435\u043d\u0438\u0435 \u043f\u0440\u0435\u043f\u0430\u0440\u0430\u0442\u043e\u0432 \u0436\u0435\u043b\u0435\u0437\u0430 \u0432\u043d\u0443\u0442\u0440\u0438\u0432\u0435\u043d\u043d\u043e (\u043d\u0435\u043f\u0440\u043e\u043f\u043e\u0440\u0446\u0438\u043e\u043d\u0430\u043b\u044c\u043d\u043e\u0435 \u0443\u0432\u0435\u043b\u0438\u0447\u0435\u043d\u0438\u0435 \u0444\u0435\u0440\u0440\u0438\u0442\u0438\u043d\u0430 \u043f\u043e \u0441\u0440\u0430\u0432\u043d\u0435\u043d\u0438\u044e \u0441 \u0437\u0430\u043f\u0430\u0441\u0430\u043c\u0438 \u0436\u0435\u043b\u0435\u0437\u0430; \u0441\u043e\u043e\u0442\u043d\u043e\u0448\u0435\u043d\u0438\u0435 \u0441\u0442\u0430\u043d\u043e\u0432\u0438\u0442\u0441\u044f \u043f\u0440\u043e\u043f\u043e\u0440\u0446\u0438\u043e\u043d\u0430\u043b\u044c\u043d\u044b\u043c \u0447\u0435\u0440\u0435\u0437 2-4 \u043d\u0435\u0434\u0435\u043b\u0438 \u043f\u043e\u0441\u043b\u0435 \u043e\u043a\u043e\u043d\u0447\u0430\u043d\u0438\u044f \u043b\u0435\u0447\u0435\u043d\u0438\u044f)6 \u0438\u043b\u0438 p.o., \u043e\u0440\u0430\u043b\u044c\u043d\u044b\u0435 \u043a\u043e\u043d\u0442\u0440\u0430\u0446\u0435\u043f\u0442\u0438\u0432\u044b4;5, \u0442\u0435\u043e\u0444\u0438\u043b\u043b\u0438\u043d4.<\/td>\n<td valign=\"top\" width=\"216\">* \u0424\u0438\u0437\u0438\u043e\u043b\u043e\u0433\u0438\u0447\u0435\u0441\u043a\u0438\u0435 \u0432\u0430\u0440\u0438\u0430\u0446\u0438\u0438: \u043d\u0435\u0441\u043a\u043e\u043b\u044c\u043a\u043e \u0431\u043e\u043b\u0435\u0435 \u043d\u0438\u0437\u043a\u0438\u0435 \u0441\u0440\u0435\u0434\u043d\u0438\u0435 \u0443\u0440\u043e\u0432\u043d\u0438 \u0443 \u0434\u0435\u0442\u0435\u04396.<\/p>\n<p>* \u041b\u0435\u043a\u0430\u0440\u0441\u0442\u0432\u0430: \u0430\u043d\u0442\u0438\u0442\u0438\u0440\u0435\u043e\u0438\u0434\u043d\u044b\u0435, \u0430\u0441\u043a\u043e\u0440\u0431\u0438\u043d\u043e\u0432\u0430\u044f \u043a\u0438\u0441\u043b\u043e\u0442\u0430, \u0434\u0435\u0444\u0435\u0440\u043e\u043a\u0441\u0430\u043c\u0438\u043d, \u043c\u0435\u0442\u0438\u043c\u0430\u0437\u043e\u043b4.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p style=\"text-align: justify;\"><strong><span style=\"font-size: 12pt;\">\u0411\u0438\u0431\u043b\u0438\u043e\u0433\u0440\u0430\u0444\u0438\u044f<\/span><\/strong><\/p>\n<div style=\"text-align: justify;\"><span style=\"font-size: 12pt;\">1. <span style=\"font-size: 10pt;\">Andrews N. Iron Deficiency and Related Disorders. In Wintrobe\u2019s Clinical Hematology. Lippincott Williams &amp; Wilkins, USA, 11 Ed., 2004, 980-1004.<\/span><\/span><\/div>\n<div style=\"text-align: justify;\"><span style=\"font-size: 10pt;\">2. Edwards C. Hemochromatosis. In Wintrobe\u2019s Clinical Hematology. Lippincott Williams &amp; Wilkins, USA, 2 ed. 2004, 1036-1049.<\/span><\/div>\n<div style=\"text-align: justify;\"><span style=\"font-size: 10pt;\">3. Frances Fischbach. Blood Studies: Hematology and Coagulation. In A Manual of Laboratory and Diagnostics Tests. Lippincott Williams &amp; Wilkins, USA, 8 Ed., 2009, 123-125.<\/span><\/div>\n<div style=\"text-align: justify;\"><span style=\"font-size: 10pt;\">4. Frances Fischbach. Effects of the Most Commonly Used Drugs on Frequently Ordered Laboratory Tests. In A Manual of Laboratory and Diagnostic Tests. Lippincott Williams &amp; Wilkins, USA, 8 Ed., 2009, 1238.<\/span><\/div>\n<div style=\"text-align: justify;\"><span style=\"font-size: 10pt;\">5. Jacques Wallach. Afec\u0163iuni hematologice. \u00cen Interpretarea testelor de diagnostic. Editura \u015etiin\u0163elor Medicale, Romania, 7 Ed., 2001, 448-450.<\/span><\/div>\n<div style=\"text-align: justify;\"><span style=\"font-size: 10pt;\">6. Joachim P. Kaltwasser. Ferritin. In Clinical Laboratory Diagnostics-Use and Assessment of Clinical Laboratory Results. Lothar Thomas.TH-Books Verlagsgesellschaft mbH, Germany, 1 Ed., 1998, 278-281.<\/span><\/div>\n<div style=\"text-align: justify;\"><span style=\"font-size: 10pt;\">7. Laborator Synevo. Referin\u0163ele specifice tehnologiei de lucru utilizate. 2010. Ref Type: Catalog.<\/span><\/div>\n<div style=\"text-align: justify;\"><span style=\"font-size: 10pt;\">8. Paul R.Finley, Harold J.Grady, Eugene S. Olsowka. Chemistry. In Laboratory Test Handbook. David S. Jacobs, Wayne R. DeMott, Paul R. Finley et.al., LEXI-COMP Inc., USA, 3 Ed., 1994, 220-222.<\/span><\/div>","protected":false},"featured_media":0,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[926],"product_tag":[],"class_list":{"0":"post-9236","1":"product","2":"type-product","3":"status-publish","5":"product_cat-markeri-anemie","7":"first","8":"instock","9":"sold-individually","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/product\/9236","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/comments?post=9236"}],"wp:attachment":[{"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/media?parent=9236"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/product_brand?post=9236"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/product_cat?post=9236"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/product_tag?post=9236"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}