{"id":9219,"date":"2020-04-23T04:31:43","date_gmt":"2020-04-23T01:31:43","guid":{"rendered":"https:\/\/www.synevo.ro\/product\/dehidroepiandrosteron-sulfat-dhea-s\/"},"modified":"2026-02-19T00:12:32","modified_gmt":"2026-02-18T22:12:32","slug":"dehidroepiandrosteron-sulfat-dhea-s","status":"publish","type":"product","link":"https:\/\/old.synevo.md\/ru\/shop\/dehidroepiandrosteron-sulfat-dhea-s\/","title":{"rendered":"\u0414\u0435\u0433\u0438\u0434\u0440\u043e\u044d\u043f\u0438\u0430\u043d\u0434\u0440\u043e\u0441\u0442\u0435\u0440\u043e\u043d\u0441\u0443\u043b\u044c\u0444\u0430\u0442 (DHEA-S)"},"content":{"rendered":"<p style=\"text-align: justify;\"><strong><em>\u041e\u0431\u0449\u0430\u044f \u0438\u043d\u0444\u043e\u0440\u043c\u0430\u0446\u0438\u044f<\/em><\/strong><\/p>\n<p style=\"text-align: justify;\">DHEA-S este un hormon steroid sintetizat dintr-un precursor de colesterol \u00een corticosuprarenal\u0103 \u00eempreun\u0103 cu cortizolul, sub controlul ACTH \u015fi al prolactinei<sup>4;7<\/sup>.<\/p>\n<p style=\"text-align: justify;\">DHEA-S poate fi metabolizat \u00een androgeni mai activi, de tipul androstendion \u015fi testosteron, care pot genera hirsutism \u015fi virilizare (inclusiv sindromul Stein-Leventhal). Numai concentra\u0163ii crescute de DHEA-S au importan\u0163\u0103 clinic\u0103: tumori produc\u0103toare de androgeni, sindrom adrenogenital etc<sup>3;5;7<\/sup>.<\/p>\n<p style=\"text-align: justify;\">DHEA-S este legat relativ puternic de albumin\u0103 \u015fi doar o mic\u0103 parte circul\u0103 liber. Se pare c\u0103 acest hormon nu se leag\u0103 de proteina de legare a hormonilor sexuali (SHBG-sex hormone binding globulin).<\/p>\n<p style=\"text-align: justify;\">Datorit\u0103 unei concentra\u0163ii serice constante (f\u0103r\u0103 varia\u0163ii diurne \u015fi pe termen lung), DHEA-S este un indicator foarte bun al produc\u0163iei androgenice a suprarenalei. Valori crescute ale DHEA-S asociate cu valori normale ale testosteronului demonstreaz\u0103 cauza suprarenalian\u0103 a excesului de androgeni<sup>4;5;7<\/sup>.<\/p>\n<p style=\"text-align: justify;\">\u00cempreun\u0103 cu testosteronul reprezint\u0103 un test screening pentru hirsutism. Aproximativ 84% dintre femeile cu hirsutism prezint\u0103 niveluri crescute de androgeni. Principalul scop al determin\u0103rii este excluderea prezen\u0163ei tumorilor produc\u0103toare de androgeni (din corticosuprarenal\u0103 sau ovar).<\/p>\n<p style=\"text-align: justify;\">DHEA-S este sc\u0103zut \u00een boala Addison. Valori sc\u0103zute ale DHEA-S \u00een lichidul amniotic sunt \u00eentalnite \u00een sindromul Down<sup>7<\/sup>.<\/p>\n<p style=\"text-align: justify;\"><strong><em>Recomandari pentru determinarea DHEA-S<\/em><\/strong><\/p>\n<p style=\"text-align: justify;\">\u00cenlocuie\u015fte determinarea excre\u0163iei urinare de 17-cetosteroizi, cu care se coreleaz\u0103; nu prezint\u0103 varia\u0163ii diurne semnificative, oferind prin aceasta un test rapid pentru secre\u0163ia anormal\u0103 de androgeni<sup>2<\/sup>.<\/p>\n<p style=\"text-align: justify;\">Determinarea sa se folose\u015fte\u00a0\u00een diagnosticul amenoreei, infertilit\u0103\u0163ii, hirsutismului, pentru identificarea sursei excesive de androgeni (\u00een hirsutism \u015fi\/sau virilizare), sindromul Stein-Leventhal (sindromul ovarelor polichistice), afec\u0163iuni ale corticosuprarenalei, dar \u015fi\u00a0 pentru a exclude tumorile produc\u0103toare de androgeni<sup>2;7<\/sup>.<\/p>\n<p style=\"text-align: justify;\"><strong><em>Preg\u0103tire pacient <\/em><\/strong><em>- <\/em>\u00e0 jeun (pe nem\u00e2ncate)<sup>6<\/sup>.<\/p>\n<p style=\"text-align: justify;\"><strong><em>Specimen recoltat <\/em><\/strong><em>- <\/em>\u0432\u0435\u043d\u043e\u0437\u043d\u0430\u044f \u043a\u0440\u043e\u0432\u044c<sup>6<\/sup>.<\/p>\n<p style=\"text-align: justify;\"><strong><em>Recipient de recoltare <\/em><\/strong><em>- <\/em>vacutainer f\u0103r\u0103 anticoagulant, cu\/f\u0103r\u0103 gel separator<sup>6<\/sup>.<\/p>\n<p style=\"text-align: justify;\"><strong><em>Prelucrare necesar\u0103 dup\u0103 recoltare<\/em><\/strong><em> - <\/em>se separ\u0103 serul prin centrifugare; se lucreaz\u0103 serul proasp\u0103t; dac\u0103 acest lucru nu este posibil, serul se p\u0103streaz\u0103 la 2-8\u00b0C sau la -20\u00b0C<sup>6<\/sup>.<\/p>\n<p style=\"text-align: justify;\"><strong><em>Volum prob\u0103<\/em><\/strong> \u2013 minim 0.5 mL ser<sup>6<\/sup>.<\/p>\n<p style=\"text-align: justify;\"><strong><em>Cauze de respingere<\/em><\/strong> <strong><em>a probei<\/em><\/strong> \u2013 specimen intens hemolizat<sup>6<\/sup>.<\/p>\n<p style=\"text-align: justify;\"><strong><em>Stabilitate prob\u0103 <\/em><\/strong><em>\u2013 2 zile<\/em> la 2-8\u00b0C ; <em>2 luni<\/em> la -20\u00b0C; nu decongela\u0163i\/recongela\u0163i<sup>6<\/sup>.<\/p>\n<p style=\"text-align: justify;\"><strong><em>Metod\u0103 <\/em><\/strong>- <span style=\"text-decoration: underline;\">imunochimic\u0103 cu detec\u0163ie prin electrochemiluminiscen\u0163\u0103 (ECLIA)<\/span><sup>6<\/sup>.<\/p>\n<p style=\"text-align: justify;\"><strong><em>Valori de referin\u0163\u0103 <\/em><\/strong><em>\u2013 s<\/em>unt dependente de v\u00e2rst\u0103 \u015fi\u00a0sex<sup>6<\/sup>:<\/p>\n<table class=\"wp-block-table w-100\" border=\"1\" cellspacing=\"0\" cellpadding=\"0\">\n<tbody>\n<tr>\n<td rowspan=\"2\" width=\"120\"><strong><em>\u00a0<\/em><\/strong><\/p>\n<p style=\"text-align: center;\"><strong><em>\u0412\u043e\u0437\u0440\u0430\u0441\u0442<\/em><\/strong><\/p>\n<\/td>\n<td colspan=\"2\" width=\"300\">\n<p style=\"text-align: center;\"><strong><em>Valori (<\/em><\/strong><strong><em>m<\/em><\/strong><strong><em>g\/dL)<\/em><\/strong><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td width=\"144\">\n<p style=\"text-align: center;\"><strong><em>B\u0103rba\u0163i<\/em><\/strong><\/p>\n<\/td>\n<td width=\"156\">\n<p style=\"text-align: center;\"><strong><em>Femei<\/em><\/strong><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td valign=\"top\" width=\"120\">\n<p style=\"text-align: center;\">1-12 luni<\/p>\n<\/td>\n<td valign=\"top\" width=\"144\">\n<p style=\"text-align: center;\">3.4-123<\/p>\n<\/td>\n<td valign=\"top\" width=\"156\">\n<p style=\"text-align: center;\">3.4-123<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td valign=\"top\" width=\"120\">\n<p style=\"text-align: center;\">1-4 ani<\/p>\n<\/td>\n<td valign=\"top\" width=\"144\">\n<p style=\"text-align: center;\">0.47-19.4<\/p>\n<\/td>\n<td valign=\"top\" width=\"156\">\n<p style=\"text-align: center;\">0.47-19.4<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td valign=\"top\" width=\"120\">\n<p style=\"text-align: center;\">5-9 ani<\/p>\n<\/td>\n<td valign=\"top\" width=\"144\">\n<p style=\"text-align: center;\">2.8-85.2<\/p>\n<\/td>\n<td valign=\"top\" width=\"156\">\n<p style=\"text-align: center;\">2.8-85.2<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td valign=\"top\" width=\"120\">\n<p style=\"text-align: center;\">10-14 ani<\/p>\n<\/td>\n<td valign=\"top\" width=\"144\">\n<p style=\"text-align: center;\">24.4-247<\/p>\n<\/td>\n<td valign=\"top\" width=\"156\">\n<p style=\"text-align: center;\">33.9-280<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td valign=\"top\" width=\"120\">\n<p style=\"text-align: center;\">15-19 ani<\/p>\n<\/td>\n<td valign=\"top\" width=\"144\">\n<p style=\"text-align: center;\">70.2-492<\/p>\n<\/td>\n<td valign=\"top\" width=\"156\">\n<p style=\"text-align: center;\">65.1-368<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td valign=\"top\" width=\"120\">\n<p style=\"text-align: center;\">20-24 ani<\/p>\n<\/td>\n<td valign=\"top\" width=\"144\">\n<p style=\"text-align: center;\">211-492<\/p>\n<\/td>\n<td valign=\"top\" width=\"156\">\n<p style=\"text-align: center;\">148-407<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td valign=\"top\" width=\"120\">\n<p style=\"text-align: center;\">25-34 ani<\/p>\n<\/td>\n<td valign=\"top\" width=\"144\">\n<p style=\"text-align: center;\">160-449<\/p>\n<\/td>\n<td valign=\"top\" width=\"156\">\n<p style=\"text-align: center;\">98.8-340<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td valign=\"top\" width=\"120\">\n<p style=\"text-align: center;\">35-44 ani<\/p>\n<\/td>\n<td valign=\"top\" width=\"144\">\n<p style=\"text-align: center;\">88.9-427<\/p>\n<\/td>\n<td valign=\"top\" width=\"156\">\n<p style=\"text-align: center;\">60.9-337<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td style=\"text-align: center;\" valign=\"top\" width=\"120\">45-54 ani<\/td>\n<td style=\"text-align: center;\" valign=\"top\" width=\"144\">44.3-331<\/td>\n<td style=\"text-align: center;\" valign=\"top\" width=\"156\">35.4-256<\/td>\n<\/tr>\n<tr>\n<td style=\"text-align: center;\" valign=\"top\" width=\"120\">55-64 ani<\/td>\n<td style=\"text-align: center;\" valign=\"top\" width=\"144\">51.7-295<\/td>\n<td style=\"text-align: center;\" valign=\"top\" width=\"156\">18.9-205<\/td>\n<\/tr>\n<tr>\n<td style=\"text-align: center;\" valign=\"top\" width=\"120\">65-74 ani<\/td>\n<td style=\"text-align: center;\" valign=\"top\" width=\"144\">33.6-249<\/td>\n<td style=\"text-align: center;\" valign=\"top\" width=\"156\">9.4-246<\/td>\n<\/tr>\n<tr>\n<td style=\"text-align: center;\" valign=\"top\" width=\"120\">&gt;=75 ani<\/td>\n<td style=\"text-align: center;\" valign=\"top\" width=\"144\">16.2-123<\/td>\n<td style=\"text-align: center;\" valign=\"top\" width=\"156\">12-154<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p style=\"text-align: justify;\">Valorile DHEA-S la <em>nou n\u0103scut<\/em> sunt puternic influen\u0163ate de transportul transplacentar de hormoni de la mam\u0103 la f\u0103t. Astfel valorile de referin\u0163\u0103 la nou-n\u0103scu\u0163i sunt:<\/p>\n<div style=\"text-align: justify; padding-left: 30px;\">\u2022 &lt;1 s\u0103pt\u0103man\u0103: 108-607 mg\/dL;<\/div>\n<div style=\"text-align: justify; padding-left: 30px;\">\u2022 1-4 s\u0103pt\u0103mani: 31.6-431 mg\/dL.<\/div>\n<p style=\"text-align: justify;\"><em>Factori de conversie: <\/em><em>m<\/em><em>mol\/L x 36.846 = <\/em><em>m<\/em><em>g\/L; <\/em><em>m<\/em><em>g\/dL x 0.02714 = <\/em><em>m<\/em><em>mol\/L; <\/em><em>m<\/em><em>g\/dL x 0.01 = <\/em><em>m<\/em><em>g\/mL.<\/em><\/p>\n<p style=\"text-align: justify;\"><strong><em>Limita de detec\u0163ie<\/em><\/strong> \u2013 0.1 \u00b5g\/dL (0.003 \u00b5mol \/L)<sup>6<\/sup>.<em>\u00a0<\/em><\/p>\n<p style=\"text-align: justify;\"><span style=\"color: #ff0000;\"><strong><em>Valori critice <\/em><\/strong>-<strong> &gt;700 <\/strong><strong>m<\/strong><strong>g\/dL<\/strong> la femei: suspiciune proces tumoral<sup>1<\/sup>.<strong><em>\u00a0<\/em><\/strong><\/span><\/p>\n<p style=\"text-align: justify;\"><strong><em>Limite \u015fi interferen\u0163e<\/em><\/strong><\/p>\n<p style=\"text-align: justify;\">\u2022 Medicamente<\/p>\n<p style=\"text-align: justify; padding-left: 30px;\"><span style=\"text-decoration: underline;\"><strong>Cre\u015fteri<\/strong><\/span>: clomifen, danazol, corticotropin<sup>8<\/sup>.<\/p>\n<p style=\"text-align: justify; padding-left: 30px;\"><span style=\"text-decoration: underline;\"><strong>Sc\u0103deri<\/strong><\/span>: dexametazona, prednison, alti glucocorticoizi, carbamazepin, testosteron<sup>8<\/sup>.<\/p>\n<p style=\"text-align: justify;\">\u2022 Interferen\u0163e analitice<\/p>\n<p style=\"text-align: justify;\">Pot produce interferen\u0163e cu unele componente ale kit-ului \u015fi conduce la rezultate neconcludente urm\u0103toarele:<\/p>\n<div style=\"text-align: justify; padding-left: 30px;\">\u2013 tratamentul cu biotin\u0103 \u00een doze mari (&gt;5 mg\/zi); de aceea se recomand\u0103 ca recoltarea de s\u00e2nge s\u0103 se fac\u0103 dup\u0103 minimum 8 ore de la ultima administrare;<\/div>\n<div style=\"text-align: justify; padding-left: 30px;\">\u2013 titrurile foarte crescute de anticorpi anti-streptavidina \u015fi anti-ruteniu<sup>6<\/sup>.<\/div>\n<p style=\"text-align: justify;\"><strong><span style=\"font-size: small;\">\u0411\u0438\u0431\u043b\u0438\u043e\u0433\u0440\u0430\u0444\u0438\u044f<\/span><\/strong><\/p>\n<div style=\"text-align: justify;\"><span style=\"font-size: small;\">1. Bernd Hinney, Wolfgang Wuttke. Ovarian function. In Clinical Laboratory Diagnostics-Use and Assessment of Clinical Laboratory Results. Lothar Thomas. TH-Books Verlagsgesellschaft mbH, Frankfurt \/Main, Germany, 1 Ed., 1998,1095.<\/span><\/div>\n<div style=\"text-align: justify;\"><span style=\"font-size: small;\">2. Henry John Bernard. Evaluation of endocrine function. In Clinical Diagnosis and Management by Laboratory Methods. ASM Press, USA, 20 Ed., 1998, 299-346.<\/span><\/div>\n<div style=\"text-align: justify;\"><span style=\"font-size: small;\">3. Ion Teodorescu Exarcu. Fiziopatologia corticosuprarenalei. \u00cen Fiziologia \u015fi fiziopatologia sistemului endocrin. Editura Medical\u0103, Rom\u00e2nia, Ed.1989, 699-727.<\/span><\/div>\n<div style=\"text-align: justify;\"><span style=\"font-size: small;\">4. Ion Teodorescu Exarcu. Corticosuprarenala. \u00cen Fiziologia \u015fi fiziopatologia sistemului endocrin. Editura Medical\u0103, Rom\u00e2nia, Ed. 1989, 680-699.<\/span><\/div>\n<div style=\"text-align: justify;\"><span style=\"font-size: small;\">5. Jacques Wallach. Afec\u0163iuni endocrine. \u00cen Interpretarea testelor de diagnostic. Editura Stiin\u0163elor Medicale, Rom\u00e2nia, 7 Ed., 2001, 834.<\/span><\/div>\n<div style=\"text-align: justify;\"><span style=\"font-size: small;\">6. Laborator Synevo. Referin\u0163ele specifice tehnologiei de lucru utilizate 2010. Ref Type: Catalog.<\/span><\/div>\n<div style=\"text-align: justify;\"><span style=\"font-size: small;\">7. Laboratory Corporation of America. Directory of Services and Interpretive Guide. Dehydroepiandrosterone (DHEA) Sulfate. www.labcorp.com 2010. Ref Type: Internet Communication.<\/span><\/div>\n<div style=\"text-align: justify;\"><span style=\"font-size: small;\">8. Norbert Tietz. General Clinical Tests. In Clinical Guide to Laboratory Tests. W.B.SAUNDERS, USA, 3 Ed., 1995, 198.<\/span><\/div>","protected":false},"excerpt":{"rendered":"<p>\u0414\u0435\u0433\u0438\u0434\u0440\u043e\u044d\u043f\u0438\u0430\u043d\u0434\u0440\u043e\u0441\u0442\u0435\u0440\u043e\u043d-\u0441\u0443\u043b\u044c\u0444\u0430\u0442 (DHEA-S) \u2013 \u044d\u0442\u043e \u0430\u043d\u0434\u0440\u043e\u0433\u0435\u043d, \u043a\u043e\u0442\u043e\u0440\u044b\u0439 \u0441\u0438\u043d\u0442\u0435\u0437\u0438\u0440\u0443\u0435\u0442\u0441\u044f \u043d\u0430\u0434\u043f\u043e\u0447\u0435\u0447\u043d\u0438\u043a\u0430\u043c\u0438. \u0423 \u043c\u0443\u0436\u0447\u0438\u043d \u043d\u0435\u0431\u043e\u043b\u044c\u0448\u043e\u0435 \u043a\u043e\u043b\u0438\u0447\u0435\u0441\u0442\u0432\u043e \u044d\u0442\u043e\u0433\u043e \u0433\u043e\u0440\u043c\u043e\u043d\u0430 \u0441\u0438\u043d\u0442\u0435\u0437\u0438\u0440\u0443\u044e\u0442 \u044f\u0438\u0447\u043a\u0438. \u041e\u043d \u0432\u043e\u0441\u043f\u0440\u043e\u0438\u0437\u0432\u043e\u0434\u0438\u0442\u0441\u044f \u0438\u0437 \u0445\u043e\u043b\u0435\u0441\u0442\u0435\u0440\u043e\u043b\u0430 \u0441\u0443\u043b\u044c\u0444\u0430\u0442\u0430. \u0411\u043e\u043b\u044c\u0448\u0430\u044f \u0447\u0430\u0441\u0442\u044c DHEA-S \u043f\u0440\u0438\u043d\u0438\u043c\u0430\u0435\u0442 \u0443\u0447\u0430\u0441\u0442\u0438\u0435 \u0432 \u044d\u043d\u0435\u0440\u0433\u0435\u0442\u0438\u0447\u0435\u0441\u043a\u043e\u043c \u043e\u0431\u043c\u0435\u043d\u0435 \u0438 \u043a\u0430\u0442\u0430\u0431\u043e\u043b\u0438\u0437\u0438\u0440\u0443\u0435\u0442\u0441\u044f \u043e\u0440\u0433\u0430\u043d\u0438\u0437\u043c\u043e\u043c. \u0422\u043e\u043b\u044c\u043a\u043e 10% \u0435\u0433\u043e \u0443\u0434\u0430\u043b\u044f\u0435\u0442\u0441\u044f \u0441 \u043c\u043e\u0447\u043e\u0439.<\/p>\n<p>\u041a\u0430\u0436\u0434\u044b\u0435 \u0441\u0443\u0442\u043a\u0438 \u0432 \u043a\u0440\u043e\u0432\u044c \u043f\u043e\u0441\u0442\u0443\u043f\u0430\u0435\u0442 10-20 \u043c\u0433 DHEA-S \u0443 \u043c\u0443\u0436\u0447\u0438\u043d \u0438 35-70 \u043c\u0433 \u0443 \u0436\u0435\u043d\u0449\u0438\u043d. \u0421\u0435\u043a\u0440\u0435\u0446\u0438\u044f \u044d\u0442\u043e\u0433\u043e \u0431\u0435\u043b\u043a\u0430 \u043d\u0435 \u0438\u043c\u0435\u0435\u0442 \u0446\u0438\u0440\u043a\u0430\u0434\u043d\u043e\u0433\u043e \u0440\u0438\u0442\u043c\u0430, \u0430 \u0442\u0430\u043a\u0436\u0435 \u0434\u043b\u044f \u043d\u0435\u0433\u043e \u043e\u0442\u0441\u0443\u0442\u0441\u0442\u0432\u0443\u044e\u0442 \u0441\u043f\u0435\u0446\u0438\u0444\u0438\u0447\u0435\u0441\u043a\u0438\u0435 \u0441\u0432\u044f\u0437\u044b\u0432\u0430\u044e\u0449\u0438\u0435 \u0441\u044b\u0432\u043e\u0440\u043e\u0442\u043e\u0447\u043d\u044b\u0435 \u0431\u0435\u043b\u043a\u0438. \u0422\u0430\u043a\u0438\u043c \u043e\u0431\u0440\u0430\u0437\u043e\u043c \u043a\u043e\u043d\u0446\u0435\u043d\u0442\u0440\u0430\u0446\u0438\u044f \u044d\u0442\u043e\u0433\u043e \u0433\u043e\u0440\u043c\u043e\u043d\u0430 \u043d\u0435 \u0437\u0430\u0432\u0438\u0441\u0438\u0442 \u043e\u0442 \u043a\u043e\u043b\u0438\u0447\u0435\u0441\u0442\u0432\u0430 \u044d\u0442\u0438\u0445 \u0431\u0435\u043b\u043a\u043e\u0432 \u0432 \u043a\u0440\u043e\u0432\u0438. \u041d\u043e DHEA-S \u043c\u043e\u0436\u0435\u0442 \u0441\u0432\u044f\u0437\u044b\u0432\u0430\u0442\u044c\u0441\u044f \u0441 \u0430\u043b\u044c\u0431\u0443\u043c\u0438\u043d\u043e\u043c.<\/p>\n<p>\u041d\u0435\u0437\u0430\u0432\u0438\u0441\u0438\u043c\u043e \u043e\u0442 DHEA-S, \u0432 \u043a\u0440\u043e\u0432\u0438 \u0446\u0438\u0440\u043a\u0443\u043b\u0438\u0440\u0443\u0435\u0442 \u0434\u0435\u0433\u0438\u0434\u0440\u043e\u044d\u043f\u0438\u0430\u043d\u0434\u0440\u043e\u0441\u0442\u0435\u0440\u043e\u043d (DHEA). \u041e\u043d \u0441\u0438\u043d\u0442\u0435\u0437\u0438\u0440\u0443\u0435\u0442\u0441\u044f \u043d\u0430\u0434\u043f\u043e\u0447\u0435\u0447\u043d\u0438\u043a\u0430\u043c\u0438 \u0438 \u0447\u0430\u0441\u0442\u0438\u0447\u043d\u043e \u043f\u043e\u043b\u043e\u0432\u044b\u043c\u0438 \u0436\u0435\u043b\u0435\u0437\u0430\u043c\u0438. DHEA \u043e\u0431\u0440\u0430\u0437\u0443\u0435\u0442\u0441\u044f \u0432 4 \u0440\u0430\u0437\u0430 \u043c\u0435\u0434\u043b\u0435\u043d\u043d\u0435\u0435, \u0447\u0435\u043c DHEA-S, \u0430 \u0443 \u043c\u0443\u0436\u0447\u0438\u043d \u0432 2 \u0440\u0430\u0437\u0430 \u043c\u0435\u0434\u043b\u0435\u043d\u043d\u0435\u0435 \u0447\u0435\u043c \u0443 \u0436\u0435\u043d\u0449\u0438\u043d. \u0421\u043a\u043e\u0440\u043e\u0441\u0442\u044c \u0435\u0433\u043e \u043c\u0435\u0442\u0430\u0431\u043e\u043b\u0438\u0437\u043c\u0430 \u0437\u043d\u0430\u0447\u0438\u0442\u0435\u043b\u044c\u043d\u043e \u0432\u044b\u0448\u0435, \u043f\u043e\u044d\u0442\u043e\u043c\u0443 \u043a\u043e\u043d\u0446\u0435\u043d\u0442\u0440\u0430\u0446\u0438\u044f \u0446\u0438\u0440\u043a\u0443\u043b\u0438\u0440\u0443\u044e\u0449\u0435\u0433\u043e DHEA \u043c\u043e\u0436\u0435\u0442 \u0431\u044b\u0442\u044c \u0432 1000 \u0440\u0430\u0437 \u043d\u0438\u0436\u0435 DHEA-S.<\/p>\n<p>\u0412\u044b\u0441\u043e\u043a\u0430\u044f \u043a\u043e\u043d\u0446\u0435\u043d\u0442\u0440\u0430\u0446\u0438\u044f \u0432 \u043a\u0440\u043e\u0432\u0438, \u0434\u043b\u0438\u0442\u0435\u043b\u044c\u043d\u044b\u0439 \u043f\u0435\u0440\u0438\u043e\u0434 \u043f\u043e\u043b\u0443\u0436\u0438\u0437\u043d\u0438 \u0438 \u0432\u044b\u0441\u043e\u043a\u0430\u044f \u0441\u0442\u0430\u0431\u0438\u043b\u044c\u043d\u043e\u0441\u0442\u044c \u043f\u043e\u0437\u0432\u043e\u043b\u044f\u044e\u0442 DHEA-S \u0431\u044b\u0442\u044c \u043e\u0442\u043b\u0438\u0447\u043d\u044b\u043c \u043f\u043e\u043a\u0430\u0437\u0430\u0442\u0435\u043b\u0435\u043c \u0430\u043d\u0434\u0440\u043e\u0433\u0435\u043d\u0441\u0435\u043a\u0440\u0435\u0442\u0438\u0440\u0443\u044e\u0449\u0435\u0439 \u0444\u0443\u043d\u043a\u0446\u0438\u0438 \u043d\u0430\u0434\u043f\u043e\u0447\u0435\u0447\u043d\u0438\u043a\u043e\u0432.<\/p>\n<p>\u0423 \u043d\u043e\u0432\u043e\u0440\u043e\u0436\u0434\u0435\u043d\u043d\u044b\u0445 \u0443\u0440\u043e\u0432\u0435\u043d\u044c \u0433\u043e\u0440\u043c\u043e\u043d\u0430 \u043e\u0447\u0435\u043d\u044c \u043d\u0438\u0437\u043e\u043a. \u041e\u043d \u043d\u0430\u0447\u0438\u043d\u0430\u0435\u0442 \u043d\u0430\u0440\u0430\u0449\u0438\u0432\u0430\u0442\u044c\u0441\u044f \u0441 6-\u043b\u0435\u0442\u043d\u0435\u0433\u043e \u0432\u043e\u0437\u0440\u0430\u0441\u0442\u0430. \u0412 \u043f\u0435\u0440\u0438\u043e\u0434 \u043f\u043e\u043b\u043e\u0432\u043e\u0433\u043e \u0441\u043e\u0437\u0440\u0435\u0432\u0430\u043d\u0438\u044f \u0443\u0440\u043e\u0432\u0435\u043d\u044c DHEA-S \u0434\u043e\u0441\u0442\u0438\u0433\u0430\u0435\u0442 \u043d\u043e\u0440\u043c\u044b \u0438 \u043e\u0441\u0442\u0430\u0435\u0442\u0441\u044f \u043d\u0430 \u044d\u0442\u043e\u043c \u0443\u0440\u043e\u0432\u043d\u0435 \u0434\u043e 40-50 \u043b\u0435\u0442. \u0417\u0430\u0442\u0435\u043c \u043a\u043e\u043b\u0438\u0447\u0435\u0441\u0442\u0432\u043e \u0433\u043e\u0440\u043c\u043e\u043d\u0430 \u043f\u043e\u0441\u0442\u0435\u043f\u0435\u043d\u043d\u043e \u0441\u043d\u0438\u0436\u0430\u0435\u0442\u0441\u044f.<\/p>\n<p>\u041f\u043e\u0432\u044b\u0448\u0435\u043d\u043d\u044b\u0439 \u0443\u0440\u043e\u0432\u0435\u043d\u044c \u0442\u0435\u0441\u0442\u043e\u0441\u0442\u0435\u0440\u043e\u043d\u0430 \u0443 \u0436\u0435\u043d\u0449\u0438\u043d \u043c\u043e\u0436\u0435\u0442 \u0438\u043c\u0435\u0442\u044c \u0441\u0432\u0435\u0440\u0445\u043f\u043e\u0447\u0435\u0447\u043d\u043e\u0435 \u0438\u043b\u0438 \u043e\u0432\u0430\u0440\u0438\u0430\u043b\u044c\u043d\u043e\u0435 \u043f\u0440\u043e\u0438\u0441\u0445\u043e\u0436\u0434\u0435\u043d\u0438\u0435. \u041f\u043e\u043a\u0430\u0437\u0430\u0442\u0435\u043b\u0438 \u043e\u043f\u0440\u0435\u0434\u0435\u043b\u0435\u043d\u0438\u044f DHEA-S \u043f\u043e\u0437\u0432\u043e\u043b\u044f\u044e\u0442 \u0432\u044b\u044f\u0432\u0438\u0442\u044c \u043f\u0440\u0438\u0447\u0438\u043d\u0443 \u043f\u0440\u043e\u0438\u0441\u0445\u043e\u0436\u0434\u0435\u043d\u0438\u044f \u0433\u0438\u043f\u0435\u0440\u0430\u043d\u0434\u0440\u043e\u0433\u0435\u043d\u0438\u0438. \u041f\u043e\u0432\u044b\u0448\u0435\u043d\u043d\u0430\u044f \u043a\u043e\u043d\u0446\u0435\u043d\u0442\u0440\u0430\u0446\u0438\u044f DHEA-S \u043f\u0440\u043e\u044f\u0432\u043b\u044f\u0435\u0442\u0441\u044f \u0442\u043e\u043b\u044c\u043a\u043e \u043f\u0440\u0438 \u0433\u0438\u043f\u0435\u0440\u0430\u043d\u0434\u0440\u043e\u0433\u0435\u043d\u0438\u0438 \u043d\u0430\u0434\u043f\u043e\u0447\u0435\u0447\u043d\u0438\u043a\u0430. \u041d\u0430\u043f\u0440\u0438\u043c\u0435\u0440, \u043f\u0440\u0438 \u043e\u043f\u0443\u0445\u043e\u043b\u044f\u0445 \u043d\u0430\u0434\u043f\u043e\u0447\u0435\u0447\u043d\u0438\u043a\u043e\u0432, \u0434\u0432\u0443\u0441\u0442\u043e\u0440\u043e\u043d\u043d\u0435\u0439 \u0433\u0438\u043f\u0435\u0440\u043f\u043b\u0430\u0437\u0438\u0438 \u043d\u0430\u0434\u043f\u043e\u0447\u0435\u0447\u043d\u0438\u043a\u043e\u0432, \u043a\u043e\u0442\u043e\u0440\u0430\u044f \u043d\u0430\u0431\u043b\u044e\u0434\u0430\u0435\u0442\u0441\u044f \u043f\u0440\u0438 \u0441\u0438\u043d\u0434\u0440\u043e\u043c\u0435 \u041a\u0443\u0448\u0438\u043d\u0433\u0430.<\/p>\n<p>\u041f\u043e\u043a\u0430\u0437\u0430\u043d\u0438\u044f \u043a \u043e\u0431\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u044e:<\/p>\n<ul>\n<li>\u041e\u043f\u0443\u0445\u043e\u043b\u0438 \u043d\u0430\u0434\u043f\u043e\u0447\u0435\u0447\u043d\u0438\u043a\u043e\u0432.<\/li>\n<li>\u0414\u0438\u0444\u0444\u0435\u0440\u0435\u043d\u0446\u0438\u0430\u043b\u044c\u043d\u0430\u044f \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0430 \u043e\u0432\u0430\u0440\u0438\u0430\u043b\u044c\u043d\u044b\u0445 \u043d\u0430\u0440\u0443\u0448\u0435\u043d\u0438\u0439.<\/li>\n<li>\u041e\u0441\u0442\u0435\u043e\u043f\u043e\u0440\u043e\u0437.<\/li>\n<li>\u0417\u0430\u0434\u0435\u0440\u0436\u043a\u0430 \u043f\u043e\u043b\u043e\u0432\u043e\u0433\u043e \u0440\u0430\u0437\u0432\u0438\u0442\u0438\u044f.<\/li>\n<li>\u0413\u0438\u0440\u0441\u0443\u0442\u0438\u0437\u043c.<\/li>\n<li>\u0412\u0438\u0440\u0438\u043b\u0438\u0437\u0430\u0446\u0438\u044f.<\/li>\n<\/ul>\n<p>\u0418\u043d\u0442\u0435\u0440\u043f\u0440\u0435\u0442\u0430\u0446\u0438\u044f \u0440\u0435\u0437\u0443\u043b\u044c\u0442\u0430\u0442\u043e\u0432<\/p>\n<p>\u041f\u043e\u0432\u044b\u0448\u0435\u043d\u043d\u044b\u0439 \u0443\u0440\u043e\u0432\u0435\u043d\u044c DHEA-S:<\/p>\n<ul>\n<li>\u043e\u043f\u0443\u0445\u043e\u043b\u0438 \u043d\u0430\u0434\u043f\u043e\u0447\u0435\u0447\u043d\u0438\u043a\u043e\u0432;<\/li>\n<li>\u043f\u043e\u043b\u0438\u043a\u0438\u0441\u0442\u043e\u0437 \u044f\u0438\u0447\u043d\u0438\u043a\u043e\u0432;<\/li>\n<li>\u0443\u0441\u043a\u043e\u0440\u0435\u043d\u043d\u043e\u0435 \u043f\u043e\u043b\u043e\u0432\u043e\u0435 \u0440\u0430\u0437\u0432\u0438\u0442\u0438\u0435 \u0443 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\u043a\u0443\u0440\u0435\u043d\u0438\u044f.<\/p>","protected":false},"featured_media":0,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[911,917],"product_tag":[],"class_list":{"0":"post-9219","1":"product","2":"type-product","3":"status-publish","5":"product_cat-markeri-endocrini","6":"product_cat-markeri-suprarenalieni","8":"first","9":"instock","10":"sold-individually","11":"shipping-taxable","12":"purchasable","13":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/product\/9219","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/comments?post=9219"}],"wp:attachment":[{"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/media?parent=9219"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/product_brand?post=9219"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/product_cat?post=9219"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/product_tag?post=9219"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}