{"id":9204,"date":"2020-04-23T04:31:15","date_gmt":"2020-04-23T01:31:15","guid":{"rendered":"https:\/\/www.synevo.ro\/product\/creatinina-serica\/"},"modified":"2026-02-19T01:07:22","modified_gmt":"2026-02-18T23:07:22","slug":"creatinina-serica","status":"publish","type":"product","link":"https:\/\/old.synevo.md\/ru\/shop\/creatinina-serica\/","title":{"rendered":"\u041a\u0440\u0435\u0430\u0442\u0438\u043d\u0438\u043d"},"content":{"rendered":"<p style=\"text-align: justify;\"><strong><em>\u041e\u0431\u0449\u0430\u044f \u0438\u043d\u0444\u043e\u0440\u043c\u0430\u0446\u0438\u044f<\/em><\/strong><\/p>\n<p style=\"text-align: justify;\">Creatinina este anhidrida creatinei (acidul metilguanidilacetic) si reprezinta forma sa de eliminare; se formeaza in tesutul muscular. Creatina este sintetizata in ficat si dupa eliberare este preluata la nivelul musculaturii in procent de 98%<sup>6<\/sup>, unde au loc fosforilari, sub aceasta forma avand rol important in stocarea energiei musculare. Cand aceasta energie musculara este solicitata pentru nevoile proceselor metabolice, fosfocreatina este scindata pana la creatinina. Cantitatea de creatina convertita in creatinina se mentine la un nivel constant, care este in raport direct cu masa de tesut muscular a organismului. La barbati 1.5% din stocul de creatina este convertit zilnic in creatinina. Creatina provenita din alimente (in special din carne) creste stocul de creatina si creatinina. Reducerea aportului proteic scade nivelul creatininei prin absenta aminoacizilor arginina si glicina, precursorii creatinei<sup>6<\/sup>.<\/p>\n<p style=\"text-align: justify;\">Creatinina este cel mai fix constituent azotat al sangelui, neinfluentat de majoritatea alimentelor, de efort, ritmul circadian sau de alte constante biologice si este corelata cu metabolismul muscular<sup>3<\/sup><sup>;6<\/sup>.<\/p>\n<p style=\"text-align: justify;\"><strong><em>Recomandari pentru determinarea creatininei serice<\/em><\/strong><\/p>\n<p style=\"text-align: justify;\">O perturbare a functiei renale reduce excretia de creatinina, determinand cresterea creatininei serice. Astfel, concentratiile de creatinina ofera o aproximare a ratei filtrarii glomerulare.<\/p>\n<p style=\"text-align: justify;\">Principala utilitate a determinarii creatininei serice este diagnosticarea insuficientei renale.<\/p>\n<p style=\"text-align: justify;\">Creatinina serica este un indicator mai specific si mai sensibil al functiei renale decat ureea. Totusi, in bolile renale cronice este util sa se determine atat creatinina cat si ureea serica (impreuna cu parametrul uree nitrogen BUN), deoarece raportul BUN\/creatinina furnizeaza mai multe informatii<sup>1<\/sup>.<\/p>\n<p style=\"text-align: justify;\">Creatinina serica se determina la prima examinare la pacienti asimptomatici sau simptomatici, la pacienti cu manifestari urinare, hipertensiune, boli renale acute si cronice, boli extrarenale cu diaree, varsaturi, transpiratii profuze, boli acute, postoperator sau la pacienti care necesita ingrijiri medicale intensive, in sepsis, soc, politraumatisme, hemodializa, in boli metabolice (diabet zaharat, hiperuricemie), sarcina, boli cu metabolism proteic crescut (mielom multiplu, acromegalie), tratament cu medicamente nefrotoxice<sup>6<\/sup>.<\/p>\n<p style=\"text-align: justify;\"><strong><em>Pregatire pacient <\/em><\/strong>\u2013 preferabil \u00e0 jeun (pe nemancate)<sup>4<\/sup>.<\/p>\n<p style=\"text-align: justify;\"><strong><em>Specimen recoltat <\/em><\/strong>\u2013 sange venos<sup>4<\/sup>.<\/p>\n<p style=\"text-align: justify;\"><strong><em>Recipient de recoltare <\/em><\/strong>\u2013 vacutainer fara anticoagulant cu\/fara gel separator<sup>4<\/sup>.<\/p>\n<p style=\"text-align: justify;\"><strong><em>Prelucrare necesara dupa recoltare<\/em><\/strong> \u2013 se separa serul prin centrifugare, se lucreaza in 4 ore; daca acest lucru nu este posibil, serul se va stoca la 2-8\u00b0C sau la -20\u00b0C<sup>4<\/sup>.<\/p>\n<p style=\"text-align: justify;\"><strong><em>Volum proba<\/em><\/strong> \u2013 minim 0.5 mL ser<sup>4<\/sup>.<\/p>\n<p style=\"text-align: justify;\"><strong><em>Cauze de respingere a probei <\/em><\/strong>\u2013 specimen hemolizat<sup>5<\/sup>; specimen recoltat de pe cateter utilizat pentru perfuzie de solutii nutritive<sup>4<\/sup>.<\/p>\n<p style=\"text-align: justify;\"><strong><em>Stabilitate proba<\/em><\/strong> \u2013 serul separat este stabil <em>4 ore<\/em> la temperatura camerei; <em>7 zile<\/em> la 2-8\u00b0C; <em>timp indelungat<\/em> la -18\u00b0C<sup>4<\/sup>.<\/p>\n<p style=\"text-align: justify;\"><strong><em>Metoda <\/em><\/strong>-\u00a0<span style=\"text-decoration: underline;\">kinetica (enzimatica colorimetrica) <u>Jaff\u00e9<\/u><\/span><sup>4<\/sup>.<\/p>\n<p style=\"text-align: justify;\"><strong><em>Valori de referinta <\/em><\/strong>\u2013 sunt dependente de varsta si sex<sup>4<\/sup>:<\/p>\n<table class=\"wp-block-table w-100\">\n<tbody>\n<tr>\n<td width=\"120\"><strong><em>\u0412\u043e\u0437\u0440\u0430\u0441\u0442<\/em><\/strong><\/td>\n<td width=\"120\"><strong><em>Valori (mg\/dL)<\/em><\/strong><\/td>\n<\/tr>\n<tr>\n<td width=\"120\">0-2 luni<\/td>\n<td width=\"120\">&lt; 0.85<\/td>\n<\/tr>\n<tr>\n<td width=\"120\">2- 12 luni<\/td>\n<td width=\"120\">&lt; 0.42<\/td>\n<\/tr>\n<tr>\n<td width=\"120\">1-2 ani<\/td>\n<td width=\"120\">&lt; 0.41<\/td>\n<\/tr>\n<tr>\n<td width=\"120\">3-4 ani<\/td>\n<td width=\"120\">&lt; 0.47<\/td>\n<\/tr>\n<tr>\n<td width=\"120\">5-6 ani<\/td>\n<td width=\"120\">&lt; 0.59<\/td>\n<\/tr>\n<tr>\n<td width=\"120\">7-8 ani<\/td>\n<td width=\"120\">&lt; 0.60<\/td>\n<\/tr>\n<tr>\n<td width=\"120\">9-10 ani<\/td>\n<td width=\"120\">&lt; 0.73<\/td>\n<\/tr>\n<tr>\n<td width=\"120\">11-12 ani<\/td>\n<td width=\"120\">&lt; 0.79<\/td>\n<\/tr>\n<tr>\n<td width=\"120\">13-14 ani<\/td>\n<td width=\"120\">&lt; 0.87<\/td>\n<\/tr>\n<tr>\n<td width=\"120\">Femei<\/td>\n<td width=\"120\">&lt; 1<\/td>\n<\/tr>\n<tr>\n<td width=\"120\">Barbati<\/td>\n<td width=\"120\">&lt; 1.2<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p style=\"text-align: justify;\"><em>Factor de conversie: mg\/dL x 88.4 = \u00b5mol\/L; \u00b5mol\/L x 0.0113 = mg\/dL. <\/em><\/p>\n<p style=\"text-align: justify;\"><strong><em>Limita de detectie<\/em><\/strong><em> - <\/em>0.03 mg\/dL (2.7 \u00b5mol\/L)<sup>4<\/sup>.<em>\u00a0<\/em><\/p>\n<p style=\"text-align: justify;\"><strong><em>Valori de referinta pentru raportul BUN\/creatinina: <\/em><\/strong>10-20<sup>3<\/sup>.<strong><em>\u00a0<\/em><\/strong><\/p>\n<p style=\"text-align: justify;\"><span style=\"color: #ff0000;\"><strong><em>Valori critice <\/em><\/strong>- <strong>&gt;10 mg\/dL<\/strong> la pacienti nedializati<sup>1<\/sup>.<\/span><\/p>\n<p style=\"text-align: justify;\"><strong><em>Interpretarea rezultatelor<\/em><\/strong><\/p>\n<table class=\"wp-block-table w-100\" border=\"1\" width=\"612\" cellspacing=\"0\" cellpadding=\"0\">\n<tbody>\n<tr>\n<td width=\"312\">\n<p style=\"text-align: center;\"><strong><em>Cresteri<\/em><\/strong><strong><em>\u00a0<\/em><\/strong><\/p>\n<\/td>\n<td width=\"300\"><strong><em>Scaderi<\/em><\/strong><strong><em>\u00a0<\/em><\/strong><\/td>\n<\/tr>\n<tr>\n<td valign=\"top\" width=\"312\">\n<p style=\"text-align: center;\">\u2022 afectiuni renale acute sau cronice de cauza glomerulara sau tubulo-interstitiala; \u2022 obstructii ale tractului\u00a0 urinar (azotemie postrenala); \u2022 scaderea perfuziei renale (azotemie prerenala): insuficienta cardiaca congestiva, soc, deshidratare; \u2022 afectiuni musculare: miastenia gravis, distrofii musculare, poliomielita; \u2022 rabdomioliza; \u2022 hipertiroidism; \u2022 gigantism, acromegalie<sup>1;3;5<\/sup>.<\/p>\n<\/td>\n<td valign=\"top\" width=\"300\">\n<p style=\"text-align: center;\">\u2022 sarcina (<em>valori normale<\/em>: 0.4-0.6 mg\/dL; un nivel de peste 0.8 mg\/dL este considerat patologic si impune solicitarea unor investigatii suplimentare);<\/p>\n<p style=\"text-align: center;\">\u2022 scaderea masei musculare; \u2022 carente proteice in dieta; \u2022 afectiuni hepatice severe<sup>1;3;5<\/sup>.<strong><em>\u00a0<\/em><\/strong><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p style=\"text-align: justify;\"><strong><em>\u00a0<\/em><\/strong><\/p>\n<table class=\"wp-block-table w-100\" border=\"1\" width=\"612\" cellspacing=\"0\" cellpadding=\"0\">\n<tbody>\n<tr>\n<td valign=\"top\" width=\"312\">\n<p style=\"text-align: center;\"><strong><em>Cresterea raportului BUN\/creatinina (&gt;20) cu niveluri normale de creatinina <\/em><\/strong><em>(azotemie prerenala)<strong>\u00a0<\/strong><\/em><\/p>\n<\/td>\n<td valign=\"top\" width=\"300\">\n<p style=\"text-align: center;\"><strong><em>Cresterea raportului BUN\/creatinina (&gt;20) cu niveluri crescute de creatinina <\/em><\/strong><em>(azotemie postrenala)<\/em><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td valign=\"top\" width=\"312\">\n<p style=\"text-align: center;\">\u2022insuficienta cardiaca, \u2022depletie de sare, \u2022deshidratare, \u2022hemoragie digestiva; \u2022stari de hipercatabolism; \u2022afectarea functiei renale asociata cu ingestie\/productie excesiva de proteine sau distructie tisulara<sup>1<\/sup><sup>;6<\/sup>.<strong><em>\u00a0<\/em><\/strong><\/p>\n<\/td>\n<td valign=\"top\" width=\"300\">\u2022 obstructii ale tractului urinar<sup>1;6<\/sup>.<\/p>\n<p style=\"text-align: center;\"><strong><em>\u00a0<\/em><\/strong><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td valign=\"top\" width=\"312\">\n<p style=\"text-align: center;\"><strong><em>Scaderea raportului BUN\/creatinina (&lt;10) cu niveluri scazute de BUN<\/em><\/strong><\/p>\n<\/td>\n<td valign=\"top\" width=\"300\">\n<p style=\"text-align: center;\"><strong><em>Scaderea raportului uree\/creatinina (&lt;10) cu niveluri crescute de creatinina<\/em><\/strong><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td valign=\"top\" width=\"312\">\n<p style=\"text-align: center;\">\u2022necroza tubulara acuta; \u2022reducerea sintezei de uree in afectiuni hepatice severe sau infometare<sup>6<\/sup>; \u2022dialize repetate; \u2022sindromul secretiei inadecvate de ADH; \u2022 sarcina<sup>1<\/sup>.<\/p>\n<\/td>\n<td valign=\"top\" width=\"300\">\n<p style=\"text-align: center;\">\u2022rabdomioliza (se elibereaza creatinina musculara); \u2022afectiuni musculare care asociaza insuficienta renala<sup>1<\/sup>.<\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p style=\"text-align: justify;\"><strong><em>Limite si interferente<\/em><\/strong><\/p>\n<p style=\"text-align: justify;\">Se inregistreaza niveluri mai crescute la barbati si la persoane cu masa musculara mare<sup>6<\/sup>.<\/p>\n<p style=\"text-align: justify;\">Aceeasi concentratie a creatininei la tineri si la varstnici nu semnifica aceeasi rata a filtrarii glomerulare (la varstnici scade clearance-ul la creatinina, dar scade si productia de creatinina)<sup>6<\/sup>.<\/p>\n<p style=\"text-align: justify;\">In conditiile scaderii perfuziei renale, cresterile creatininei serice se produc mai lent decat cele ale ureei.<\/p>\n<p style=\"text-align: justify;\">Deoarece este necesara o pierdere de 50% din functia renala pentru ca valorile creatininei sa creasca de la 1.0 la 2.0 mg\/dl, creatinina serica nu poate fi considerata un indicator sensibil in caz de leziuni renale usoare pana la moderate<sup>3<\/sup>.<\/p>\n<p style=\"text-align: justify;\">Nivelul seric al creatininei poate fi utilizat pentru estimarea ratei filtrarii glomerulare numai in conditii de echilibru, cand rata sintezei creatininei este egala cu eliminarea. Pentru verificarea acestei stari sunt necesare doua determinari la interval de 24 ore; diferente de peste 10% pot indica ca nu exista o astfel de stare de echilibru<sup>6<\/sup>.<\/p>\n<p style=\"text-align: justify;\">In alterari ale functiei renale, rata filtrarii glomerulare este supraestimata prin nivelul creatininei serice, deoarece eliminarea creatininei nu se datoreaza filtrarii glomerulare, ci secretiei tubulare si creatinina este de asemenea eliminata prin mucoasa intestinala, fiind aparent metabolizata de catre creatininazele bacteriene intestinale<sup>6<\/sup>.<\/p>\n<p style=\"text-align: justify;\">O dieta cu un continut excesiv de carne poate determina cresteri ale creatininei serice (15-30% din creatinina excretata zilnic provine din alimente)<sup>1<\/sup>.<\/p>\n<p style=\"text-align: justify;\">\u2022 Medicamente<\/p>\n<p style=\"text-align: justify; padding-left: 30px;\"><span style=\"text-decoration: underline;\"><strong>Cresteri<\/strong><\/span>: acebutolol, acetaminofen, acid ascorbic, acid nalidixic, acyclovir, albendazol, antiacide alcaline, alprazolam, amikacin, amilorid, amiodarona, amfotericina B, asparaginaza, aspirina, azatioprina, azitromicina, aztreonam, barbiturice, bisoprolol, capreomicin, captopril, carbamazepin, carvedilol, caspofungin, cefaclor, cefamandol, cefazolin, cefixim, cefoperazon, cefotaxim, cefotetan, cefoxitin, cefpodoxim, ceftibuten, ceftizoxim, ceftriaxon, cefuroxim, cefalexin, cefaloridin, cefalotin, cetirizin, clorotiazida, clorpropamid, clortalidona, cidofovir, cimetidina, cinoxacin, ciprofloxacin, cisplatin, claritromicina, clofibrat, clonidina, cotrimoxazol, colistin, ciclosporina, danazol, dextran, diclofenac, disopiramida, diuretice, doxorubicina, doxiciclina, enalapril, enfluran, epoetin alfa, eprosartan, etambutol, etidronat, etretinat, fenoprofen, flucitozina, fludarabina, foscarnet, furosemid, gemfibrozil, gentamicina, griseofulvina, hidralazina, hidroclorotiazid, hidroxiuree, ibuprofen, idarubicina, imipramina, indometacin, isotretinoin, kanamicina, ketoprofen, labetalol, leuprolid, levodopa, lidocaina, lisinopril, litiu, losartan, lovastatin, manitol, acid mefenamic, meropenem, meticilina, metotrexat, metildopa, metilprednisolon, metoprolol, mitomicina, mitoxantrona, moxalactam, naproxen, neomicina, netilmicina, nifedipina, nitrofurantoin, norfloxacin, ofloxacina, oxacilina, pamidronat, penicilamina, penicilina, pentamidina, pentostatin, piperacilina, piroxicam, prednison, propafenona, ramipril, ranitidina, streptokinaza, streptomicina, streptozocin, sulfametoxazol, sulfasalazina, sulindac, tacrolimus, tetraciclina, ticarcilina, ticlopidin, tobramicina, tramadol, trandolapril, tretinoin, triamteren, triazolam, trimetroprim, ursodiol, valsartan, vancomicina, vasopresina, vitamina D<sup>2<\/sup>.<\/p>\n<p style=\"text-align: justify; padding-left: 30px;\"><strong><span style=\"text-decoration: underline;\">Scaderi<\/span>:<\/strong> acid valproic, canabis, zidovudina<sup>2<\/sup>, glucocorticoizi<sup>6<\/sup>.<\/p>\n<p style=\"text-align: justify;\">\u2022 Interferente analitice<\/p>\n<p style=\"text-align: justify;\">La pacientii cu macroglobulinemie Waldenstr\u0151m pot aparea rezultate fals crescute datorita precipitarii IgM.<\/p>\n<p style=\"text-align: justify;\">Dobesilatul de calciu (Dexium) da valori fals scazute la concentratii peste 5 mg\/L. Rezultate fals crescute pot da N-etilglicina si DL-prolina la concentratii terapeutice.<\/p>\n<p style=\"text-align: justify;\">Cefalosporinele nu influenteaza acest test<sup>4<\/sup>.<\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: small;\">\u00a0<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: small;\">\u0411\u0438\u0431\u043b\u0438\u043e\u0433\u0440\u0430\u0444\u0438\u044f<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: small;\">1. Frances Fischbach. Chemistry studies. In A Manual of Laboratory and Diagnostic Tests. Lippincott Williams &amp; Wilkins, USA, 7 Ed., 2009; 375-377.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: small;\">2. Frances Fischbach. Effects of the on Laboratory Tests. In A Manual of Laboratory and Diagnostic Tests. Lippincott Williams &amp; Wilkins, USA, 8 Ed., 2009; 1234-1235.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: small;\">3. Jacques Wallach. Analizele de sange. In Interpretarea testelor de diagnostic. Editura Stiintelor Medicale, Romania, 7 Ed., 2001; 68-69.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: small;\">4. Laborato rSynevo. Referintele specifice tehnologiei de lucru utilizate 2015. Ref Type: Catalog.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: small;\">5. Laboratory Corporation of America. Directory of Services and Interpretive Guide. Creatinine, Serum. www.labcorp.com. 2010. Ref Type: Internet Communication.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: small;\">6. Lothar Thomas. Kidney and urinary tract. In Clinical Laboratory Diagnostics-Use and Assessment of Clinical laboratory Results. TH-Books Verlagsgesellschaft mbH, Frankfurt \/Main, Germany, 1 Ed., 1998; 366-370, 375.<\/span><\/p>","protected":false},"excerpt":{"rendered":"<p>\u041a\u0440\u0435\u0430\u0442\u0438\u043d\u0438\u043d &#8211; \u043a\u043e\u043d\u0435\u0447\u043d\u044b\u0439 \u043f\u0440\u043e\u0434\u0443\u043a\u0442 \u0440\u0430\u0441\u043f\u0430\u0434\u0430 \u043a\u0440\u0435\u0430\u0442\u0438\u043d\u0430, \u043a\u043e\u0442\u043e\u0440\u044b\u0439 \u0438\u0433\u0440\u0430\u0435\u0442 \u0432\u0430\u0436\u043d\u0443\u044e \u0440\u043e\u043b\u044c \u0432 \u044d\u043d\u0435\u0440\u0433\u0435\u0442\u0438\u0447\u0435\u0441\u043a\u043e\u043c \u043e\u0431\u043c\u0435\u043d\u0435 \u043c\u044b\u0448\u0435\u0447\u043d\u043e\u0439 \u0438 \u0434\u0440\u0443\u0433\u0438\u0445 \u0442\u043a\u0430\u043d\u0435\u0439. \u041a\u0440\u0435\u0430\u0442\u0438\u043d \u0441\u0438\u043d\u0442\u0435\u0437\u0438\u0440\u0443\u0435\u0442\u0441\u044f, \u0432 \u043e\u0441\u043d\u043e\u0432\u043d\u043e\u043c, \u0432 \u043f\u0435\u0447\u0435\u043d\u0438, \u043e\u0442\u043a\u0443\u0434\u0430 \u043e\u043d \u0441 \u0442\u043e\u043a\u043e\u043c \u043a\u0440\u043e\u0432\u0438 \u043f\u043e\u0441\u0442\u0443\u043f\u0430\u0435\u0442 \u0432 \u043c\u044b\u0448\u0435\u0447\u043d\u0443\u044e \u0442\u043a\u0430\u043d\u044c. \u041f\u043e\u0441\u043b\u0435 \u0440\u044f\u0434\u0430 \u043f\u043e\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u0442\u0435\u043b\u044c\u043d\u044b\u0445 \u0431\u0438\u043e\u0445\u0438\u043c\u0438\u0447\u0435\u0441\u043a\u0438\u0445 \u0440\u0435\u0430\u043a\u0446\u0438\u0439 \u043a\u0440\u0435\u0430\u0442\u0438\u043d \u043f\u0440\u0435\u0432\u0440\u0430\u0449\u0430\u0435\u0442\u0441\u044f \u0432 \u043a\u0440\u0435\u0430\u0442\u0438\u043d\u0438\u043d, \u043a\u043e\u0442\u043e\u0440\u044b\u0439 \u0432\u044b\u0441\u0432\u043e\u0431\u043e\u0436\u0434\u0430\u0435\u0442\u0441\u044f \u0438\u0437 \u043c\u0438\u043e\u0446\u0438\u0442\u043e\u0432 \u0438 \u043a\u0440\u043e\u0432\u044c\u044e \u0434\u043e\u0441\u0442\u0430\u0432\u043b\u044f\u0435\u0442\u0441\u044f \u0432 \u043f\u043e\u0447\u043a\u0438, \u043e\u0442\u043a\u0443\u0434\u0430 \u044d\u043a\u0441\u043a\u0440\u0435\u0442\u0438\u0440\u0443\u0435\u0442\u0441\u044f \u0432\u043c\u0435\u0441\u0442\u0435 \u0441 \u043c\u043e\u0447\u0435\u0432\u0438\u043d\u043e\u0439. \u0412 \u043d\u043e\u0440\u043c\u0435 \u043a\u0440\u0435\u0430\u0442\u0438\u043d\u0438\u043d \u0441\u0432\u043e\u0431\u043e\u0434\u043d\u043e \u0444\u0438\u043b\u044c\u0442\u0440\u0443\u0435\u0442\u0441\u044f \u0432 \u043f\u043e\u0447\u0435\u0447\u043d\u044b\u0445 \u043a\u043b\u0443\u0431\u043e\u0447\u043a\u0430\u0445 \u0438 \u0434\u0430\u043b\u0435\u0435, \u043d\u0435 \u043f\u043e\u0434\u0432\u0435\u0440\u0433\u0430\u044f\u0441\u044c \u043e\u0431\u0440\u0430\u0442\u043d\u043e\u043c\u0443 \u0432\u0441\u0430\u0441\u044b\u0432\u0430\u043d\u0438\u044e \u0438\u043b\u0438 \u0434\u043e\u043f\u043e\u043b\u043d\u0438\u0442\u0435\u043b\u044c\u043d\u043e\u0439 \u0441\u0435\u043a\u0440\u0435\u0446\u0438\u0438 \u0432 \u043a\u0430\u043d\u0430\u043b\u044c\u0446\u0430\u0445, \u043f\u043e\u043b\u043d\u043e\u0441\u0442\u044c\u044e \u0432\u044b\u0432\u043e\u0434\u0438\u0442\u0441\u044f \u0441 \u043c\u043e\u0447\u043e\u0439 \u0438\u0437 \u043e\u0440\u0433\u0430\u043d\u0438\u0437\u043c\u0430. \u041f\u043e\u044d\u0442\u043e\u043c\u0443 \u0443\u0432\u0435\u043b\u0438\u0447\u0435\u043d\u0438\u0435 \u043a\u043e\u043d\u0446\u0435\u043d\u0442\u0440\u0430\u0446\u0438\u0438 \u043a\u0440\u0435\u0430\u0442\u0438\u043d\u0438\u043d\u0430 \u0432 \u0441\u044b\u0432\u043e\u0440\u043e\u0442\u043a\u0435 \u043a\u0440\u043e\u0432\u0438 \u0433\u043e\u0432\u043e\u0440\u0438\u0442 \u043e\u0431 \u0443\u043c\u0435\u043d\u044c\u0448\u0435\u043d\u0438\u0438 \u0443\u0440\u043e\u0432\u043d\u044f \u043f\u043e\u0447\u0435\u0447\u043d\u043e\u0439 \u0444\u0438\u043b\u044c\u0442\u0440\u0430\u0446\u0438\u0438.<\/p>\n<p>\u041a\u043e\u043d\u0446\u0435\u043d\u0442\u0440\u0430\u0446\u0438\u044f \u043a\u0440\u0435\u0430\u0442\u0438\u043d\u0438\u043d\u0430 \u0432 \u043a\u0440\u043e\u0432\u0438 \u0437\u0430\u0432\u0438\u0441\u0438\u0442 \u043e\u0442 \u0435\u0433\u043e \u043e\u0431\u0440\u0430\u0437\u043e\u0432\u0430\u043d\u0438\u044f \u0438 \u0432\u044b\u0432\u0435\u0434\u0435\u043d\u0438\u044f. \u042d\u043a\u0441\u043a\u0440\u0435\u0446\u0438\u044f \u043a\u0440\u0435\u0430\u0442\u0438\u043d\u0438\u043d\u0430 \u043e\u0442\u0440\u0430\u0436\u0430\u0435\u0442 \u043c\u0435\u0442\u0430\u0431\u043e\u043b\u0438\u0437\u043c \u043c\u044b\u0448\u0435\u0447\u043d\u043e\u0433\u043e \u0431\u0435\u043b\u043a\u0430. \u041f\u0440\u0438 \u0438\u0441\u0442\u043e\u0449\u0435\u043d\u0438\u0438 \u043c\u044b\u0448\u0435\u0447\u043d\u043e\u0439 \u043c\u0430\u0441\u0441\u044b \u043d\u0430\u0431\u043b\u044e\u0434\u0430\u0435\u0442\u0441\u044f \u0441\u043d\u0438\u0436\u0435\u043d\u0438\u0435 \u044d\u043a\u0441\u043a\u0440\u0435\u0446\u0438\u0438 \u043a\u0440\u0435\u0430\u0442\u0438\u043d\u0438\u043d\u0430 \u0441 \u043c\u043e\u0447\u043e\u0439. \u0412 \u0443\u0441\u043b\u043e\u0432\u0438\u044f\u0445 \u0443\u043c\u0435\u043d\u044c\u0448\u0435\u043d\u0438\u044f \u043f\u043e\u0447\u0435\u0447\u043d\u043e\u0439 \u043f\u0435\u0440\u0444\u0443\u0437\u0438\u0438 \u043f\u043e\u0432\u044b\u0448\u0435\u043d\u0438\u044f \u0441\u044b\u0432\u043e\u0440\u043e\u0442\u043e\u0447\u043d\u043e\u0433\u043e \u043a\u0440\u0435\u0430\u0442\u0438\u043d\u0438\u043d\u0430 \u043f\u0440\u043e\u0438\u0441\u0445\u043e\u0434\u044f\u0442 \u043c\u0435\u0434\u043b\u0435\u043d\u043d\u0435\u0435, \u0447\u0435\u043c \u043f\u043e\u0432\u044b\u0448\u0435\u043d\u0438\u044f \u0443\u0440\u043e\u0432\u043d\u044f \u043c\u043e\u0447\u0435\u0432\u0438\u043d\u044b. \u0422\u0430\u043a \u043a\u0430\u043a \u043f\u0440\u043e\u0438\u0441\u0445\u043e\u0434\u0438\u0442 \u0432\u044b\u043d\u0443\u0436\u0434\u0435\u043d\u043d\u044b\u0439 \u0441\u043f\u0430\u0434 \u0444\u0443\u043d\u043a\u0446\u0438\u043e\u043d\u0438\u0440\u043e\u0432\u0430\u043d\u0438\u044f \u043f\u043e\u0447\u0435\u043a \u043d\u0430 50% \u043f\u0440\u0438 \u0443\u0432\u0435\u043b\u0438\u0447\u0435\u043d\u0438\u0438 \u0437\u043d\u0430\u0447\u0435\u043d\u0438\u0439 \u043a\u0440\u0435\u0430\u0442\u0438\u043d\u0438\u043d\u0430, \u0442\u043e \u043a\u0440\u0435\u0430\u0442\u0438\u043d\u0438\u043d \u043d\u0435 \u043c\u043e\u0436\u0435\u0442 \u0440\u0430\u0441\u0441\u043c\u0430\u0442\u0440\u0438\u0432\u0430\u0442\u044c\u0441\u044f \u043a\u0430\u043a \u0447\u0443\u0432\u0441\u0442\u0432\u0438\u0442\u0435\u043b\u044c\u043d\u044b\u0439 \u0438\u043d\u0434\u0438\u043a\u0430\u0442\u043e\u0440 \u043f\u0440\u0438 \u043f\u043e\u0432\u0440\u0435\u0436\u0434\u0435\u043d\u0438\u044f\u0445 \u043f\u043e\u0447\u0435\u043a \u043b\u0435\u0433\u043a\u043e\u0439 \u0438\u043b\u0438 \u0443\u043c\u0435\u0440\u0435\u043d\u043d\u043e\u0439 \u0441\u0442\u0435\u043f\u0435\u043d\u0438. \u0423\u0440\u043e\u0432\u0435\u043d\u044c \u043a\u0440\u0435\u0430\u0442\u0438\u043d\u0438\u043d\u0430 \u0432 \u0441\u044b\u0432\u043e\u0440\u043e\u0442\u043a\u0435 \u043c\u043e\u0436\u0435\u0442 \u0431\u044b\u0442\u044c \u0438\u0441\u043f\u043e\u043b\u044c\u0437\u043e\u0432\u0430\u043d \u0434\u043b\u044f \u043e\u0446\u0435\u043d\u043a\u0438 \u043a\u043b\u0443\u0431\u043e\u0447\u043a\u043e\u0432\u043e\u0439 \u0444\u0438\u043b\u044c\u0442\u0440\u0430\u0446\u0438\u0438 \u0442\u043e\u043b\u044c\u043a\u043e \u0432 \u0443\u0441\u043b\u043e\u0432\u0438\u044f\u0445 \u0431\u0430\u043b\u0430\u043d\u0441\u0430, \u043a\u043e\u0433\u0434\u0430 \u0441\u043a\u043e\u0440\u043e\u0441\u0442\u044c \u0441\u0438\u043d\u0442\u0435\u0437\u0430 \u043a\u0440\u0435\u0430\u0442\u0438\u043d\u0438\u043d\u0430 \u0440\u0430\u0432\u043d\u0430 \u0441\u043a\u043e\u0440\u043e\u0441\u0442\u0438 \u0435\u0433\u043e \u044d\u043b\u0438\u043c\u0438\u043d\u0430\u0446\u0438\u0438. \u0413\u043b\u0430\u0432\u043d\u0430\u044f \u0446\u0435\u043d\u043d\u043e\u0441\u0442\u044c \u043e\u043f\u0440\u0435\u0434\u0435\u043b\u0435\u043d\u0438\u044f \u0441\u044b\u0432\u043e\u0440\u043e\u0442\u043e\u0447\u043d\u043e\u0433\u043e \u043a\u0440\u0435\u0430\u0442\u0438\u043d\u0438\u043d\u0430 &#8212; \u044d\u0442\u043e \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0430 \u043f\u043e\u0447\u0435\u0447\u043d\u043e\u0439 \u043d\u0435\u0434\u043e\u0441\u0442\u0430\u0442\u043e\u0447\u043d\u043e\u0441\u0442\u0438.<\/p>\n<p>\u0421\u044b\u0432\u043e\u0440\u043e\u0442\u043e\u0447\u043d\u044b\u0439 \u043a\u0440\u0435\u0430\u0442\u0438\u043d\u0438\u043d \u044f\u0432\u043b\u044f\u0435\u0442\u0441\u044f \u0431\u043e\u043b\u0435\u0435 \u0441\u043f\u0435\u0446\u0438\u0444\u0438\u0447\u043d\u044b\u043c \u0438 \u0431\u043e\u043b\u0435\u0435 \u0447\u0443\u0432\u0441\u0442\u0432\u0438\u0442\u0435\u043b\u044c\u043d\u044b\u043c \u043f\u043e\u043a\u0430\u0437\u0430\u0442\u0435\u043b\u0435\u043c \u0444\u0443\u043d\u043a\u0446\u0438\u0438 \u043f\u043e\u0447\u0435\u043a, \u0432 \u043e\u0442\u043b\u0438\u0447\u0438\u0435 \u043e\u0442 \u043c\u043e\u0447\u0435\u0432\u0438\u043d\u044b, \u043e\u0434\u043d\u0430\u043a\u043e \u043f\u0440\u0438 \u0445\u0440\u043e\u043d\u0438\u0447\u0435\u0441\u043a\u0438\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u044f\u0445 \u043f\u043e\u0447\u0435\u043a \u0438\u0441\u043f\u043e\u043b\u044c\u0437\u0443\u0435\u0442\u0441\u044f \u043e\u043f\u0440\u0435\u0434\u0435\u043b\u0435\u043d\u0438\u0435 \u043a\u0430\u043a \u043a\u0440\u0435\u0430\u0442\u0438\u043d\u0438\u043d\u0430, \u0442\u0430\u043a \u0438 \u043c\u043e\u0447\u0435\u0432\u0438\u043d\u044b \u0432 \u0441\u044b\u0432\u043e\u0440\u043e\u0442\u043a\u0435, \u0432 \u0441\u043e\u0447\u0435\u0442\u0430\u043d\u0438\u0438 \u0441 \u043f\u043e\u043a\u0430\u0437\u0430\u0442\u0435\u043b\u0435\u043c \u0430\u0437\u043e\u0442\u0430 \u043c\u043e\u0447\u0435\u0432\u0438\u043d\u044b (BUN). \u041e\u043f\u0440\u0435\u0434\u0435\u043b\u0435\u043d\u0438\u0435 \u043a\u043e\u043d\u0446\u0435\u043d\u0442\u0440\u0430\u0446\u0438\u0438 \u043a\u0440\u0435\u0430\u0442\u0438\u043d\u0438\u043d\u0430 \u0432 \u043a\u0440\u043e\u0432\u0438 \u0438 \u043c\u043e\u0447\u0435 \u0438\u0441\u043f\u043e\u043b\u044c\u0437\u0443\u044e\u0442 \u0434\u043b\u044f \u0440\u0430\u0441\u0447\u0451\u0442\u0430 \u0432\u0435\u043b\u0438\u0447\u0438\u043d\u044b \u043a\u043b\u0443\u0431\u043e\u0447\u043a\u043e\u0432\u043e\u0439 \u0444\u0438\u043b\u044c\u0442\u0440\u0430\u0446\u0438\u0438 \u0438 \u043e\u0446\u0435\u043d\u043a\u0438 \u0444\u0443\u043d\u043a\u0446\u0438\u0438 \u043f\u043e\u0447\u0435\u043a (\u043f\u0440\u043e\u0431\u0430 \u0420\u0435\u0431\u0435\u0440\u0433\u0430).<\/p>\n<table>\n<tbody>\n<tr>\n<td colspan=\"2\" width=\"262\"><b>\u041f\u043e\u043a\u0430\u0437\u0430\u0442\u0435\u043b\u044c<\/b><\/td>\n<td colspan=\"2\" width=\"367\"><b>\u0425\u0430\u0440\u0430\u043a\u0442\u0435\u0440\u0438\u0441\u0442\u0438\u043a\u0430<\/b><\/td>\n<\/tr>\n<tr>\n<td colspan=\"2\" width=\"262\"><b>\u041c\u0430\u0442\u0435\u0440\u0438\u0430\u043b<\/b><\/td>\n<td colspan=\"2\" width=\"367\">\u0412\u0435\u043d\u043e\u0437\u043d\u0430\u044f\u00a0\u043a\u0440\u043e\u0432\u044c<\/td>\n<\/tr>\n<tr>\n<td colspan=\"2\" width=\"262\"><b>\u041f\u0440\u0430\u0432\u0438\u043b\u0430\u00a0\u043f\u043e\u0434\u0433\u043e\u0442\u043e\u0432\u043a\u0438\u00a0\u043f\u0430\u0446\u0438\u0435\u043d\u0442\u0430<\/b><\/td>\n<td colspan=\"2\" width=\"367\">\u0421\u0442\u0430\u043d\u0434\u0430\u0440\u0442\u043d\u044b\u0435<\/td>\n<\/tr>\n<tr>\n<td colspan=\"2\" width=\"262\"><b>\u0422\u0440\u0430\u043d\u0441\u043f\u043e\u0440\u0442\u043d\u0430\u044f\u00a0\u0441\u0440\u0435\u0434\u0430,\u00a0\u043f\u0440\u043e\u0431\u0438\u0440\u043a\u0430<\/b><\/td>\n<td colspan=\"2\" width=\"367\">\u0412\u0430\u043a\u0443\u0442\u0430\u0439\u043d\u0435\u0440\u00a0\u0441\/\u0431\u0435\u0437\u00a0\u0430\u043d\u0442\u0438\u043a\u043e\u0430\u0433\u0443\u043b\u044f\u043d\u0442\u0430\u00a0\u0441\/\u0431\u0435\u0437\u00a0\u0433\u0435\u043b\u0435\u0432\u043e\u0439\u00a0\u0444\u0430\u0437\u044b<\/td>\n<\/tr>\n<tr>\n<td colspan=\"2\" width=\"262\"><b>\u041f\u0440\u0430\u0432\u0438\u043b\u0430\u00a0\u0438\u00a0\u0443\u0441\u043b\u043e\u0432\u0438\u044f\u00a0\u0442\u0440\u0430\u043d\u0441\u043f\u043e\u0440\u0442\u0438\u0440\u043e\u0432\u043a\u0438,\u00a0\u0441\u0442\u0430\u0431\u0438\u043b\u044c\u043d\u043e\u0441\u0442\u044c\u00a0\u043f\u0440\u043e\u0431\u044b<\/b><\/td>\n<td colspan=\"2\" width=\"367\">\u0421\u0442\u0430\u043d\u0434\u0430\u0440\u0442\u043d\u044b\u0435<\/td>\n<\/tr>\n<tr>\n<td colspan=\"2\" width=\"262\"><b>\u041c\u0435\u0442\u043e\u0434\u00a0\u0442\u0435\u0441\u0442\u0438\u0440\u043e\u0432\u0430\u043d\u0438\u044f<\/b><\/td>\n<td colspan=\"2\" width=\"367\">\u041a\u0438\u043d\u0435\u0442\u0438\u0447\u0435\u0441\u043a\u0438\u0439<\/td>\n<\/tr>\n<tr>\n<td colspan=\"2\" width=\"262\"><\/td>\n<td colspan=\"2\" width=\"367\"><\/td>\n<\/tr>\n<tr>\n<td colspan=\"4\" width=\"629\"><\/td>\n<\/tr>\n<tr>\n<td width=\"252\"><\/td>\n<td colspan=\"3\" width=\"376\"><\/td>\n<\/tr>\n<tr>\n<td colspan=\"4\" width=\"629\"><b>\u0418\u043d\u0442\u0435\u0440\u0444\u0435\u0440\u0438\u0440\u0443\u044e\u0449\u0438\u0435\u00a0\u0444\u0430\u043a\u0442\u043e\u0440\u044b.\u00a0\u041c\u0435\u0434\u0438\u043a\u0430\u043c\u0435\u043d\u0442\u044b<\/b><\/td>\n<\/tr>\n<tr>\n<td colspan=\"3\" width=\"479\"><b>\u041f\u043e\u0432\u044b\u0448\u0430\u044e\u0442<\/b><\/td>\n<td width=\"149\"><b>\u0421\u043d\u0438\u0436\u0430\u044e\u0442<\/b><\/td>\n<\/tr>\n<tr>\n<td colspan=\"3\" width=\"479\">\u0410\u0446\u0435\u0431\u0443\u0442\u043e\u043b\u043e\u043b,\u00a0\u0430\u0441\u043a\u043e\u0440\u0431\u0438\u043d\u043e\u0432\u0430\u044f\u00a0\u043a\u0438\u0441\u043b\u043e\u0442\u0430,\u00a0\u043d\u0430\u043b\u0438\u0434\u0438\u043a\u0441\u043e\u0432\u0430\u044f\u00a0\u043a\u0438\u0441\u043b\u043e\u0442\u0430,\u00a0\u0430\u0446\u0438\u043a\u043b\u043e\u0432\u0438\u0440,\u00a0\u0449\u0435\u043b\u043e\u0447\u043d\u044b\u0435\u00a0\u0430\u043d\u0442\u0430\u0446\u0438\u0434\u044b,\u00a0\u0430\u043c\u0438\u043e\u0434\u0430\u0440\u043e\u043d,\u00a0\u0430\u043c\u0444\u043e\u0442\u0435\u0440\u0438\u0446\u0438\u043d\u00a0\u0412,<\/p>\n<p>\u0430\u0441\u043f\u0430\u0440\u0430\u0433\u0438\u043d\u0430\u0437\u0430,\u00a0\u0430\u0441\u043f\u0438\u0440\u0438\u043d,\u00a0\u0430\u0437\u0438\u0442\u0440\u043e\u043c\u0438\u0446\u0438\u043d,\u00a0\u0431\u0430\u0440\u0431\u0438\u0442\u0443\u0440\u0430\u0442\u044b,\u00a0\u043a\u0430\u043f\u0442\u043e\u043f\u0440\u0438\u043b,\u00a0\u043a\u0430\u0440\u0431\u0430\u043c\u0430\u0437\u0435\u043f\u0438\u043d,\u00a0\u0446\u0435\u0444\u0430\u0437\u043e\u043b\u0438\u043d,\u00a0\u0446\u0435\u0444\u0438\u043a\u0441\u0438\u043c,\u00a0\u0446\u0435\u0444\u043e\u0442\u0435\u0442\u0430\u043d,\u00a0\u0446\u0435\u0444\u043e\u043a\u0441\u0438\u0442\u0438\u043d<\/p>\n<p>,\u00a0\u0446\u0435\u0444\u0442\u0440\u0438\u0430\u043a\u0441\u043e\u043d,\u00a0\u0446\u0435\u0444\u0443\u0440\u043e\u043a\u0441\u0438\u043c,\u00a0\u0446\u0438\u043c\u0435\u0442\u0438\u0434\u0438\u043d,\u00a0\u0446\u0438\u043f\u0440\u043e\u0444\u043b\u043e\u043a\u0441\u0430\u0446\u0438\u043d,\u00a0\u043a\u043b\u0430\u0440\u0438\u0442\u0440\u043e\u043c\u0438\u0446\u0438\u043d,\u00a0\u0434\u0438\u043a\u043b\u043e\u0444\u0435\u043d\u0430\u043a,\u00a0\u0434\u0438\u0443\u0440\u0435\u0442\u0438\u043a\u0438,\u00a0\u044d\u043d\u0430\u043b\u0430\u043f\u0440\u0438\u043b,\u00a0\u044d\u0442\u0430\u043c\u0431\u0443\u0442\u043e\u043b,<\/p>\n<p>\u0433\u0435\u043d\u0442\u0430\u043c\u0438\u0446\u0438\u043d,\u00a0\u0441\u0442\u0440\u0435\u043f\u0442\u043e\u043a\u0438\u043d\u0430\u0437\u0430,\u00a0\u0441\u0442\u0440\u0435\u043f\u0442\u043e\u043c\u0438\u0446\u0438\u043d,\u00a0\u0442\u0440\u0438\u0430\u043c\u0442\u0435\u0440\u0435\u043d,\u00a0\u0442\u0440\u0438\u0430\u0437\u043e\u043b\u0430\u043c,\u00a0\u0442\u0440\u0438\u043c\u0435\u0442\u043e\u043f\u0440\u0438\u043c,\u00a0\u0432\u0430\u0437\u043e\u043f\u0440\u0435\u0441\u0441\u0438\u043d<\/td>\n<td width=\"149\">\u0413\u043b\u044e\u043a\u043e\u043a\u043e\u0440\u0442\u0438\u043a\u043e\u0438\u0434\u044b<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<table>\n<tbody>\n<tr>\n<td colspan=\"2\" width=\"629\"><b>\u041f\u043e\u043a\u0430\u0437\u0430\u043d\u0438\u044f\u00a0\u043a\u00a0\u043d\u0430\u0437\u043d\u0430\u0447\u0435\u043d\u0438\u044e<\/b><\/td>\n<\/tr>\n<tr>\n<td colspan=\"2\" width=\"629\"><b>\u041a\u0440\u0435\u0430\u0442\u0438\u043d\u0438\u043d<\/b><b>\u00a0<\/b><b>&#8212;\u00a0\u043e\u0434\u0438\u043d\u00a0\u0438\u0437\u00a0\u043c\u0430\u0440\u043a\u0435\u0440\u043e\u0432\u00a0\u043d\u0430\u0440\u0443\u0448\u0435\u043d\u0438\u044f\u00a0\u0430\u0437\u043e\u0442\u0438\u0441\u0442\u043e\u0433\u043e\u00a0\u043e\u0431\u043c\u0435\u043d\u0430\u00a0<\/b><\/p>\n<p>\u00b7\u00a0\u041e\u0441\u0442\u0440\u044b\u0435\u00a0\u0438\u00a0\u0445\u0440\u043e\u043d\u0438\u0447\u0435\u0441\u043a\u0438\u0435\u00a0\u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u044f\u00a0\u043c\u043e\u0447\u0435\u0432\u044b\u0434\u0435\u043b\u0438\u0442\u0435\u043b\u044c\u043d\u043e\u0439\u00a0\u0441\u0438\u0441\u0442\u0435\u043c\u044b;<\/p>\n<p>\u00b7\u00a0\u0430\u0440\u0442\u0435\u0440\u0438\u0430\u043b\u044c\u043d\u0430\u044f\u00a0\u0433\u0438\u043f\u0435\u0440\u0442\u0435\u043d\u0437\u0438\u044f;<\/p>\n<p>\u00b7\u00a0\u043e\u0441\u0442\u0440\u044b\u0435\u00a0\u0432\u043e\u0441\u043f\u0430\u043b\u0438\u0442\u0435\u043b\u044c\u043d\u044b\u0435\u00a0\u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u044f;<\/p>\n<p>\u00b7\u00a0\u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u044f,\u00a0\u0441\u043e\u043f\u0440\u043e\u0432\u043e\u0436\u0434\u0430\u044e\u0449\u0438\u0435\u0441\u044f\u00a0\u043d\u0430\u0440\u0443\u0448\u0435\u043d\u0438\u0435\u043c\u00a0\u043e\u0431\u043c\u0435\u043d\u0430\u00a0\u0432\u0435\u0449\u0435\u0441\u0442\u0432;<\/p>\n<p>\u00b7\u00a0\u0441\u043e\u0441\u0442\u043e\u044f\u043d\u0438\u044f\u00a0\u043f\u043e\u0441\u043b\u0435\u00a0\u0445\u0438\u0440\u0443\u0440\u0433\u0438\u0447\u0435\u0441\u043a\u0438\u0445\u00a0\u043e\u043f\u0435\u0440\u0430\u0446\u0438\u0439,\u00a0\u043d\u0443\u0436\u0434\u0430\u044e\u0449\u0438\u0445\u0441\u044f\u00a0\u0432\u00a0\u0438\u043d\u0442\u0435\u043d\u0441\u0438\u0432\u043d\u043e\u0439\u00a0\u0442\u0435\u0440\u0430\u043f\u0438\u0438,\u00a0\u043f\u0440\u0438\u00a0\u0441\u0435\u043f\u0441\u0438\u0441\u0435,\u00a0\u0448\u043e\u043a\u0435,\u00a0\u043c\u043d\u043e\u0436\u0435\u0441\u0442\u0432\u0435\u043d\u043d\u044b\u0445\u00a0\u0442\u0440\u0430\u0432\u043c\u0430\u0445,<\/p>\n<p>\u0433\u0435\u043c\u043e\u0434\u0438\u0430\u043b\u0438\u0437\u0435<\/td>\n<\/tr>\n<tr>\n<td colspan=\"2\" width=\"629\"><b>\u0418\u043d\u0442\u0435\u0440\u043f\u0440\u0435\u0442\u0430\u0446\u0438\u044f\u00a0\u0440\u0435\u0437\u0443\u043b\u044c\u0442\u0430\u0442\u043e\u0432<\/b><\/td>\n<\/tr>\n<tr>\n<td width=\"311\"><b>\u041f\u043e\u0432\u044b\u0448\u0435\u043d\u0438\u0435\u00a0\u0443\u0440\u043e\u0432\u043d\u044f<\/b><\/td>\n<td width=\"317\"><b>\u0421\u043d\u0438\u0436\u0435\u043d\u0438\u0435\u00a0\u0443\u0440\u043e\u0432\u043d\u044f<\/b><\/td>\n<\/tr>\n<tr>\n<td width=\"311\">\u00b7\u00a0\u041e\u0441\u0442\u0440\u044b\u0435\u00a0\u0438\u00a0\u0445\u0440\u043e\u043d\u0438\u0447\u0435\u0441\u043a\u0438\u0435\u00a0\u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u044f\u00a0\u043f\u043e\u0447\u0435\u043a;<\/p>\n<p>\u00b7\u00a0\u043e\u0431\u0441\u0442\u0440\u0443\u043a\u0446\u0438\u044f\u00a0\u043c\u043e\u0447\u0435\u0432\u044b\u0432\u043e\u0434\u044f\u0449\u0438\u0445\u00a0\u043f\u0443\u0442\u0435\u0439;<\/p>\n<p>\u00b7\u00a0\u0441\u043d\u0438\u0436\u0435\u043d\u043d\u0430\u044f\u00a0\u043f\u043e\u0447\u0435\u0447\u043d\u0430\u044f\u00a0\u043f\u0435\u0440\u0444\u0443\u0437\u0438\u044f;<\/p>\n<p>\u00b7\u00a0\u0437\u0430\u0441\u0442\u043e\u0439\u043d\u0430\u044f\u00a0\u0441\u0435\u0440\u0434\u0435\u0447\u043d\u0430\u044f\u00a0\u043d\u0435\u0434\u043e\u0441\u0442\u0430\u0442\u043e\u0447\u043d\u043e\u0441\u0442\u044c;<\/p>\n<p>\u00b7\u00a0\u0448\u043e\u043a\u043e\u0432\u044b\u0435\u00a0\u0441\u043e\u0441\u0442\u043e\u044f\u043d\u0438\u044f,\u00a0\u0441\u043e\u0441\u0442\u043e\u044f\u043d\u0438\u044f,\u00a0\u0441\u043e\u043f\u0440\u043e\u0432\u043e\u0436\u0434\u0430\u044e\u0449\u0438\u0435\u0441\u044f\u00a0\u0434\u0435\u0433\u0438\u0434\u0440\u0430\u0442\u0430\u0446\u0438\u0435\u0439;<\/p>\n<p>\u00b7\u00a0\u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u044f\u00a0\u043c\u044b\u0448\u0435\u0447\u043d\u043e\u0439\u00a0\u0442\u043a\u0430\u043d\u0438\u00a0(\u0442\u044f\u0436\u0435\u043b\u0430\u044f\u00a0\u043c\u0438\u0430\u0441\u0442\u0435\u043d\u0438\u044f,\u00a0\u043c\u044b\u0448\u0435\u0447\u043d\u0430\u044f\u00a0\u0434\u0438\u0441\u0442\u0440\u043e\u0444\u0438\u044f,\u00a0\u043f\u043e\u043b\u0438\u043e\u043c\u0438\u0435\u043b\u0438\u0442);<\/p>\n<p>\u00b7\u00a0\u0440\u0430\u0431\u0434\u043e\u043c\u0438\u043e\u043b\u0438\u0437;<\/p>\n<p>\u00b7\u00a0\u0433\u0438\u043f\u0435\u0440\u0442\u0438\u0440\u0435\u043e\u0437;<\/p>\n<p>\u00b7\u00a0\u0430\u043a\u0440\u043e\u043c\u0435\u0433\u0430\u043b\u0438\u044f\u00a0\u0438\u00a0\u0433\u0438\u0433\u0430\u043d\u0442\u0438\u0437\u043c;<\/p>\n<p>\u00b7\u00a0\u043b\u0443\u0447\u0435\u0432\u0430\u044f\u00a0\u0431\u043e\u043b\u0435\u0437\u043d\u044c;<\/p>\n<p>\u00b7\u00a0\u043f\u0440\u0435\u043e\u0431\u043b\u0430\u0434\u0430\u043d\u0438\u0435\u00a0\u043c\u044f\u0441\u043d\u043e\u0439\u00a0\u043f\u0438\u0449\u0438\u00a0\u0432\u00a0\u0440\u0430\u0446\u0438\u043e\u043d\u0435<\/td>\n<td width=\"317\">\u00b7\u00a0\u0422\u044f\u0436\u0435\u043b\u044b\u0435\u00a0\u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u044f\u00a0\u043f\u0435\u0447\u0435\u043d\u0438;<\/p>\n<p>\u00b7\u00a0\u0441\u043d\u0438\u0436\u0435\u043d\u0438\u0435\u00a0\u043c\u044b\u0448\u0435\u0447\u043d\u043e\u0439\u00a0\u043c\u0430\u0441\u0441\u044b;<\/p>\n<p>\u00b7\u00a0\u043d\u0435\u0434\u043e\u0441\u0442\u0430\u0442\u043e\u043a\u00a0\u0431\u0435\u043b\u043a\u0430\u00a0\u0432\u00a0\u0440\u0430\u0446\u0438\u043e\u043d\u0435\u00a0\u043f\u0438\u0442\u0430\u043d\u0438\u044f;<\/p>\n<p>\u00b7\u00a0\u0431\u0435\u0440\u0435\u043c\u0435\u043d\u043d\u043e\u0441\u0442\u044c\u00a0(\u043e\u0441\u043e\u0431\u0435\u043d\u043d\u043e\u00a01-2\u00a0\u0442\u0440\u0438\u043c\u0435\u0441\u0442\u0440);<\/p>\n<p>\u00b7\u00a0\u043f\u043e\u0436\u0438\u043b\u043e\u0439\u00a0\u0432\u043e\u0437\u0440\u0430\u0441\u0442;<\/p>\n<p>\u00b7\u00a0\u043f\u043e\u043b\u00a0(\u0443\u00a0\u043c\u0443\u0436\u0447\u0438\u043d\u00a0\u0441\u043e\u0434\u0435\u0440\u0436\u0430\u043d\u0438\u0435\u00a0\u043a\u0440\u0435\u0430\u0442\u0438\u043d\u0438\u043d\u0430\u00a0\u0432\u044b\u0448\u0435,\u00a0\u0447\u0442\u043e\u00a0\u0441\u0432\u044f\u0437\u0430\u043d\u043e\u00a0\u0441<\/p>\n<p>\u0431\u043e\u043b\u0435\u0435\u00a0\u0432\u044b\u0441\u043e\u043a\u0438\u043c\u00a0\u043e\u0431\u044a\u0435\u043c\u043e\u043c\u00a0\u043c\u044b\u0448\u0435\u0447\u043d\u043e\u0439\u00a0\u0442\u043a\u0430\u043d\u0438)<\/td>\n<\/tr>\n<\/tbody>\n<\/table>","protected":false},"featured_media":0,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[953],"product_tag":[],"class_list":{"0":"post-9204","1":"product","2":"type-product","3":"status-publish","5":"product_cat-teste-de-biochimie","7":"first","8":"instock","9":"sold-individually","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/product\/9204","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/comments?post=9204"}],"wp:attachment":[{"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/media?parent=9204"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/product_brand?post=9204"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/product_cat?post=9204"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/product_tag?post=9204"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}