{"id":9174,"date":"2020-04-23T04:30:17","date_gmt":"2020-04-23T01:30:17","guid":{"rendered":"https:\/\/www.synevo.ro\/product\/bicarbonat-eco2\/"},"modified":"2026-02-18T23:37:49","modified_gmt":"2026-02-18T21:37:49","slug":"bicarbonat-eco2","status":"publish","type":"product","link":"https:\/\/old.synevo.md\/ru\/shop\/bicarbonat-eco2\/","title":{"rendered":"\u0411\u0438\u043a\u0430\u0440\u0431\u043e\u043d\u0430\u0442\u044b (ECO2)"},"content":{"rendered":"

Sinonime<\/em><\/strong> \u2013 rezerva alcalina, CO2<\/sub>. \u00a0<\/strong><\/p>\n

Informatii generale si recomandari pentru determinarea bicarbonatului<\/em><\/strong><\/p>\n

Dioxidul de carbon total este alcatuit din CO2 <\/sub>aflat in solutie sau legat de proteine, HCO3<\/sub>-<\/sup>, CO3<\/sub>2-<\/sup> si H2<\/sub>CO3<\/sub>. In practica, 80-90% din CO2<\/sub> total este reprezentat de ionul bicarbonat (HCO3<\/sub>-<\/sup>)4<\/sup>.<\/p>\n

Bicarbonatul constituie cea de a doua fractiune anionica plasmatica, de aceea concentratia sa este un indicator important al distributiei electrolitilor si al deficitului de anioni. Impreuna cu determinarea pH-ului sanguin, dozarea bicarbonatului este utila in diagnosticul si tratamentul numeroaselor afectiuni insotite de tulburari ale echilibrului acido-bazic de cauza respiratorie sau metabolica3<\/sup>.<\/p>\n

Cel mai frecvent, o valoare anormala a HCO3<\/sub>-<\/sup> semnifica o tulburare metabolica, mai degraba decat una respiratorie; astfel, scaderea HCO3<\/sub>-<\/sup> indica acidoza metabolica (ex.: diabet cu cetoacidoza) si cresterea HCO3<\/sub>-<\/sup> indica alcaloza metabolica (indusa, de exemplu, de varsaturi prelungite)2<\/sup>.<\/p>\n

In acidoza respiratorie se produce ca mecanism compensator reabsorbtia HCO3<\/sub>- <\/sup>la nivelul tubilor renali, iar concentratia serica a HCO3<\/sub>- <\/sup>se modifica in functie de presiunea partiala a CO2<\/sub> (PaCO2<\/sub>):<\/p>\n

-in faza acuta HCO3<\/sub>- <\/sup>creste cu 1 mmol\/L pentru fiecare crestere cu 10mmHg a PaCO2<\/sub>;<\/p>\n

-in faza cronica HCO3<\/sub>-<\/sup> creste cu 3.5 mmol\/L pentru fiecare crestere cu 10mmHg a PaCO2.<\/sub><\/p>\n

Pe de alta parte, in alcaloza respiratorie mecanismul compensator este reprezentat de cresterea excretiei renale a HCO3<\/sub>-<\/sup>, iar concentratia serica a HCO3<\/sub>-<\/sup> se modifica astfel:<\/p>\n

-in faza acuta HCO3<\/sub>- <\/sup>scade cu 2 mmol\/L pentru fiecare scadere cu 10mmHg a PaCO2<\/sub>;<\/p>\n

\u2013 in faza cronica HCO3<\/sub>-<\/sup> scade cu 5 mmol\/L pentru fiecare scadere cu 10mmHg a PaCO2<\/sub>1;2;3<\/sup>.<\/sub><\/p>\n

Pregatire pacient <\/em><\/strong>\u2013 \u00e0 jeun (pe nemancate) sau postprandial3<\/sup>.<\/p>\n

Specimen recoltat <\/em><\/strong>\u2013 sange venos3<\/sup>.<\/p>\n

Cantitate recoltata<\/em><\/strong> \u2013 cat permite vacuumul3<\/sup>.<\/p>\n

Recipient de recoltare <\/em><\/strong>\u2013 vacutainer fara anticoagulant, cu\/fara gel separator3<\/sup>.<\/p>\n

Prelucrare necesara dupa recoltare<\/em><\/strong> \u2013 se separa serul prin centrifugare; tubul trebuie sa ramana inchis ermetic pana in momentul testarii, pentru a impiedica eliberarea CO2<\/sub> in atmosfera3<\/sup>.<\/p>\n

Cauze de respingere a probei <\/em><\/strong>\u2013 specimen hemolizat3<\/sup>.<\/p>\n

Stabilitate proba <\/em><\/strong>\u2013 serul separat si pastrat in tuburi inchise ermetic este stabil cateva zile<\/em> la 2-8\u00baC3<\/sup>.<\/p>\n

Metoda <\/em><\/strong>- <\/em>enzimatica (cu fosfoenolpiruvat carboxilaza)<\/span>3<\/sup>.<\/p>\n

Valori de referinta<\/em><\/strong> \u2013 22-29 mmol\/L.<\/p>\n

Factor de conversie: mmol\/L = mEq\/L<\/em>3<\/sup>.<\/em><\/p>\n

Valori critice <\/em><\/strong>- <\/em>nivel scazut: <10 mmol\/L<\/strong>; nivel crescut: >40 mmol\/L<\/strong>1<\/sup>.<\/span><\/p>\n

Limita de detectie <\/em><\/strong>\u2013 1.5mmol\/l (1.5mEq\/L)3<\/sup>.<\/p>\n

Interpretarea rezultatelor<\/em><\/strong>2<\/sup>\u00a0<\/em><\/strong><\/p>\n\n\n\n\n\n\n
Cresteri<\/em><\/strong><\/td>\n<\/tr>\n
Alcaloza metabolica<\/strong><\/p>\n

\u2022 varsaturi prelungite, aspiratie gastrica, fistula gastrocolica, adenom vilos de colon,<\/p>\n

\u2022 hiperaldosteronism, \u2022 tratament diuretic, \u2022 diaree cronica, \u2022 administrare de antiacide.<\/p>\n

Acidoza respiratorie<\/strong><\/p>\n

\u2022 depresia centrilor respiratori: traumatisme, infectii, droguri, \u2022 afectiuni neuromusculare: poliomielita, miopatie, sindrom Guillain-Barr\u00e9, \u2022 afectiuni toraco-pulmonare: hidrotorax, pneumotorax, BPOC, edem pulmonar, astm bronsic.<\/p>\n

Acidoza respiratorie cu alcaloza metabolica<\/strong><\/td>\n<\/tr>\n

Scaderi<\/em><\/strong><\/td>\n<\/tr>\n
Acidoza metabolica<\/strong><\/p>\n

\u2022 insuficienta renala, \u2022 acidoza tubulara renala, \u2022 cetoacidoza: diabet, inanitie, alcoolism, \u2022 acidoza lactica, \u2022 intoxicatia cu salicilat, metanol, etilenglicol, \u2022 nefropatii obstructive,<\/p>\n

\u2022 ureterosigmoidostomie, \u2022 fistula vezico-colica, \u2022 diaree acuta, \u2022 deficit de mineralocorticoizi,<\/p>\n

\u2022 administrare de HCl, NH4<\/sub>Cl, inhibitori de anhidraza carbonica.<\/p>\n

Alcaloza respiratorie<\/strong><\/p>\n

\u2022 anxietate, isterie, \u2022 sarcina, \u2022 afectiuni SNC: hipoxemie, infectii, traumatisme, encefalopatie hepatica.<\/p>\n

Acidoza metabolica cu alcaloza respiratorie<\/strong><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Limite si\u00a0 interferente<\/em><\/strong><\/p>\n

\u2022 Interferente analitice<\/p>\n

In cazuri foarte rare prezenta gamapatiei, in special IgM (macroglobulinemia Waldenstr\u00f6m) poate determina rezultate eronate3<\/sup>.<\/p>\n

\u00a0<\/span><\/p>\n

\u0411\u0438\u0431\u043b\u0438\u043e\u0433\u0440\u0430\u0444\u0438\u044f<\/span><\/p>\n

1. Frances Fischbach. Arterial Blood Gases. In A Manual of Laboratory and Diagnostic Tests. Lippincott Williams & Wilkins, USA, 8 Ed., 2009, 983-986.<\/span><\/p>\n

2. Jacques Wallach. Boli metabolice si ereditare. In Interpretarea testelor de diagnostic. Editura Stiintelor Medicale, Romania, 7 Ed., 2001, 653-666.<\/span><\/p>\n

3. Laborator Synevo. Referinte specifice tehnologiei de lucru utilizate 2010. Ref Type: Catalog.<\/span><\/p>\n

4. Laboratory Corporation of America. Directory of Services and Interpretive Guide. Carbon Dioxide, Total. www.labcorp.com 2010. Ref Type: Internet Communication.<\/span><\/p>","protected":false},"excerpt":{"rendered":"

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<\/td>\n<\/td>\n<\/tr>\n
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    \u00b7\u00a0\u041d\u0430\u0440\u0443\u0448\u0435\u043d\u0438\u044f\u00a0\u041a\u041e\u0421\u00a0(\u0438\u0441\u043f\u043e\u043b\u044c\u0437\u0443\u0435\u0442\u0441\u044f\u00a0\u0441\u00a0\u043e\u043f\u0440\u0435\u0434\u0435\u043b\u0435\u043d\u0438\u0435\u043c\u00a0\u0440\u041d\u00a0\u043a\u0440\u043e\u0432\u0438)<\/td>\n<\/tr>\n
    \u0418\u043d\u0442\u0435\u0440\u043f\u0440\u0435\u0442\u0430\u0446\u0438\u044f\u00a0\u0440\u0435\u0437\u0443\u043b\u044c\u0442\u0430\u0442\u043e\u0432<\/b><\/td>\n<\/tr>\n
    \u041f\u043e\u0432\u044b\u0448\u0435\u043d\u0438\u0435\u00a0\u0443\u0440\u043e\u0432\u043d\u044f<\/b><\/td>\n\u0421\u043d\u0438\u0436\u0435\u043d\u0438\u0435\u00a0\u0443\u0440\u043e\u0432\u043d\u044f<\/b><\/td>\n<\/tr>\n
    \n
      \n
    • \u0420\u0435\u0441\u043f\u0438\u0440\u0430\u0442\u043e\u0440\u043d\u044b\u0439 \u0430\u0446\u0438\u0434\u043e\u0437<\/li>\n
    • \u043c\u0435\u0442\u0430\u0431\u043e\u043b\u0438\u0447\u0435\u0441\u043a\u0438\u0439 \u0430\u043b\u043a\u0430\u043b\u043e\u0437<\/li>\n<\/ul>\n<\/td>\n
    		\n
      \n
    • \u041c\u0435\u0442\u0430\u0431\u043e\u043b\u0438\u0447\u0435\u0441\u043a\u0438\u0439 \u0430\u0446\u0438\u0434\u043e\u0437<\/li>\n
    • \u0440\u0435\u0441\u043f\u0438\u0440\u0430\u0442\u043e\u0440\u043d\u044b\u0439 \u0430\u043b\u043a\u0430\u043b\u043e\u0437.<\/li>\n
    • \u041b\u0438\u043f\u0438\u0434\u0435\u043c\u0438\u044f<\/li>\n
    • \u0433\u0435\u043c\u043e\u043b\u0438\u0437<\/li>\n<\/ul>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>","protected":false},"featured_media":0,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[953],"product_tag":[],"class_list":{"0":"post-9174","1":"product","2":"type-product","3":"status-publish","5":"product_cat-teste-de-biochimie","7":"first","8":"instock","9":"sold-individually","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/product\/9174","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/comments?post=9174"}],"wp:attachment":[{"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/media?parent=9174"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/product_brand?post=9174"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/product_cat?post=9174"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/product_tag?post=9174"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}