{"id":9166,"date":"2020-04-23T04:29:59","date_gmt":"2020-04-23T01:29:59","guid":{"rendered":"https:\/\/www.synevo.ro\/product\/apolipoproteina-a1\/"},"modified":"2026-02-18T23:36:20","modified_gmt":"2026-02-18T21:36:20","slug":"apolipoproteina-a1","status":"publish","type":"product","link":"https:\/\/old.synevo.md\/ru\/shop\/apolipoproteina-a1\/","title":{"rendered":"\u0410\u043f\u043e\u043b\u0438\u043f\u043e\u043f\u0440\u043e\u0442\u0435\u0438\u043d \u04101"},"content":{"rendered":"

\u041e\u0431\u0449\u0430\u044f \u0438\u043d\u0444\u043e\u0440\u043c\u0430\u0446\u0438\u044f<\/em><\/strong><\/p>\n

Apolipoproteinele sunt componente proteice ale lipoproteinelor \u015fi au rolul de a evalua riscul de boal\u0103 coronarian\u0103. Apolipoproteina A (APO A) este componentul principal al HDL (90%)3<\/sup>, iar apolipoproteina B (APO B) este componentul principal al LDL-ului, cu rol \u00een reglarea sintezei \u015fi metabolismului colesterolului3<\/sup>. Lipidele \u015fi lipoproteinele sunt molecule a c\u0103ror compozi\u0163ie \u015fi concentra\u0163ie sunt influen\u0163ate de varia\u0163iile biologice normale, \u00een schimb nivelurile APO A-1 \u015fi APO B sunt mai stabile \u015fi se coreleaza mai bine cu severitatea \u015fi extinderea afect\u0103rii cardiovasculare1;4<\/sup>; 6<\/sup>.<\/p>\n

Nu s-a ajuns \u00eenc\u0103 la un consens dac\u0103 APO A-1 este un test mai fidel\u00a0\u00een evaluarea riscului de boal\u0103 coronarian\u0103 decat HDL-colesterol8<\/sup>.<\/div>\n
Raportul APO A-1\/APO B are o sensibilitate \u015fi specificitate mai mare dec\u00e2t raportul LDL\/HDL colesterol sau raportul HDL colesterol\/trigliceride 9<\/sup>.<\/div>\n
De asemenea, nivelele Apo A-1 se coreleaz\u0103 cu rata de supravie\u0163uire a pacien\u0163ilor cu infarct miocardic sau arteriopatie periferic\u01032;6<\/sup>.<\/div>\n

Recomand\u0103ri pentru determinarea apolipoproteinelor<\/em><\/strong>\u00a0<\/strong><\/p>\n

\u2022 evaluarea pacien\u0163ilor predispu\u015fi la boala coronarian\u0103;<\/div>\n
\u2022 stabilirea diagnosticului bolii Tangier;<\/div>\n
\u2022 nivelul borderline al colesterolului;<\/div>\n
\u2022 raportul colesterol\/HDL crescut, cu valoare normala a colesterolului;<\/div>\n
\u2022 valori normale ale profilului lipidic la copii \u015fi adul\u0163i cu istoric familial pozitiv;<\/div>\n
\u2022 pacien\u0163i cu hipertrigliceridemie care au risc de boal\u0103 coronarian\u0103 3<\/sup>;7;<\/sup>4<\/sup>.<\/div>\n

Preg\u0103tire pacient<\/em><\/strong> - <\/em>pacientul nu m\u0103n\u00e2nc\u0103 cu 12-14 ore \u00eenaintea recolt\u0103rii5<\/sup>.<\/p>\n

Specimen recoltat<\/em><\/strong> - <\/em>\u0432\u0435\u043d\u043e\u0437\u043d\u0430\u044f \u043a\u0440\u043e\u0432\u044c5<\/sup>.<\/p>\n

Recipient de recoltare <\/em><\/strong>-<\/em> vacutainer f\u0103r\u0103 anticoagulant cu\/f\u0103r\u0103 gel separator5<\/sup>.<\/p>\n

Prelucrare necesar\u0103 dup\u0103 recoltare<\/em><\/strong> - <\/em>se separ\u0103 serul prin centrifugare \u00een ziua recolt\u0103rii5<\/sup>.<\/p>\n

Volum prob\u0103<\/em><\/strong> -<\/em> minim 0.5 mL ser5<\/sup>.<\/p>\n

Cauze de respingere a probei<\/em><\/strong> - <\/em>specimen intens hemolizat \/recoltat interprandial5;6<\/sup>.<\/p>\n

Stabilitate prob\u0103<\/em><\/strong> - <\/em>\u00a0serul separat este stabil 24 ore<\/em> la 20-25\u00baC, 3 zile<\/em> la 4-8\u00baC; 2 luni <\/em>\u00a0la -20\u00baC 5<\/sup>.<\/p>\n

Metod\u0103 <\/em><\/strong>- <\/em>imunoturbidimetric\u0103<\/span>5<\/sup><\/span>.<\/span><\/p>\n

Valori de referin\u0163\u0103\u00a0 APO A-1<\/em><\/strong>5<\/sup>; <\/strong><\/p>\n\n\n\n\n\n
\n

Sex<\/em><\/strong><\/p>\n<\/td>\n

\n

Valori de referin\u0163a (g\/L)<\/em><\/strong><\/p>\n<\/td>\n<\/tr>\n

\n

Femei<\/em><\/strong><\/p>\n<\/td>\n

\n

1.08-2.25<\/p>\n<\/td>\n<\/tr>\n

\n

Barba\u0163i<\/em><\/strong><\/p>\n<\/td>\n

\n

1.04-2.02<\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\u00a0<\/em><\/strong>Valori de referin\u0163\u0103\u00a0 APO B<\/em><\/strong>5<\/sup>; <\/em><\/strong><\/p>\n\n\n\n\n\n
\n

Sex<\/em><\/strong><\/p>\n<\/td>\n

\n

Valori de referin\u0163\u0103 (g\/L)<\/em><\/strong><\/p>\n<\/td>\n<\/tr>\n

\n

Femei<\/em><\/strong><\/p>\n<\/td>\n

\n

0.60-1.17<\/p>\n<\/td>\n<\/tr>\n

\n

B\u0103rba\u0163i<\/em><\/strong><\/p>\n<\/td>\n

\n

0.66-1.33<\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\u00a0<\/em><\/strong>Valori de referin\u0163\u0103\u00a0 APO A-1\/APO B<\/em><\/strong>5<\/sup>; <\/em><\/strong><\/p>\n\n\n\n\n\n
\n

Sex<\/em><\/strong><\/p>\n<\/td>\n

\n

Raport APO A-I\/APO B<\/em><\/strong><\/p>\n<\/td>\n<\/tr>\n

\n

Femei<\/em><\/strong><\/p>\n<\/td>\n

\n

0.94-1.33<\/p>\n<\/td>\n<\/tr>\n

\n

B\u0103rbati<\/em><\/strong><\/p>\n<\/td>\n

\n

0,80-1.33<\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Factori de conversie5<\/sup>:<\/p>\n

APO A-1: g\/L x 35.7 = \u03bcmol\/L<\/div>\n
APO B: g\/L x 3.79 = \u03bcmol\/L<\/div>\n
<\/div>\n
Limita de detec\u0163<\/em><\/strong>ie<\/em><\/strong> \u2013 APO B: 0.046 g\/L (4.6mg\/dL sau 0.17 \u03bcmol\/L);<\/div>\n
\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 \u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 \u2013 APO A-1: 0.058 g\/L (5.8 mg\/dL sau 2.07 \u03bcmol\/L)5<\/sup>.<\/div>\n

Interpretarea rezultatelor<\/em><\/strong><\/p>\n\n\n\n\n\n\n
\n

Cre\u015fterea APO A-1<\/em><\/strong><\/p>\n<\/td>\n

\n

Sc\u0103derea APO A-1<\/em><\/strong><\/p>\n<\/td>\n<\/tr>\n

\n
\u2022 hiper-alfa-lipoproteinemie familial\u0103<\/div>\n
\u2022 sarcin\u0103<\/div>\n
\u2022 tratament estrogenic<\/div>\n
\u2022 consum de alcool<\/div>\n
\u2022 efort fizic3;<\/sup>4<\/sup><\/div>\n<\/td>\n
\n
\u2022 diet\u0103<\/div>\n
\u2022 fumat<\/div>\n
\u2022 boala Tangier<\/div>\n
\u2022 hipoalfalipoproteinemie familial\u0103<\/div>\n
\u2022 diabet zaharat<\/div>\n
\u2022 hemodializ\u0103<\/div>\n
\u2022 infec\u0163ii<\/div>\n
\u2022 beta-lipoproteinemie<\/div>\n
\u2022 deficit de Apo C-II3;<\/sup>4<\/sup><\/div>\n
\u2022 deficit de Apo A-I-CIII<\/div>\n
\u2022 hipertrigliceridemie (familial\u0103)<\/div>\n
\u2022 boala coronarian\u0103 prematur\u0103<\/div>\n
\u2022 afectare hepatocelulara<\/div>\n
\u2022 sindrom nefrotic \u015fi boal\u0103 renal\u01033;4<\/sup><\/div>\n<\/td>\n<\/tr>\n
\n

Cre\u015fterea APO B<\/em><\/strong><\/p>\n<\/td>\n

\n

Sc\u0103derea APO B<\/em><\/strong><\/p>\n<\/td>\n<\/tr>\n

\n
\u2022 hiperlipoproteinemie<\/div>\n
\u2022 deficit de apoproteina E<\/div>\n
\u2022 hiper-apo-beta-lipoproteinemie familial\u0103<\/div>\n
\u2022 sindrom nefrotic<\/div>\n
\u2022 sarcin\u0103<\/div>\n
\u2022 obstruc\u0163ie biliar\u0103<\/div>\n
\u2022 hemodializ\u0103<\/div>\n
\u2022 fumat<\/div>\n
\u2022 diabet<\/div>\n
\u2022 hipotiroidism<\/div>\n
\u2022 disglobulinemie<\/div>\n
\u2022 porfirie<\/div>\n
\u2022 Sindrom Cushing3;<\/sup>4<\/sup><\/div>\n<\/td>\n
\n
\u2022 afec\u0163iuni hepatice<\/div>\n
\u2022 hipo \u015fi abetalipoproteinemie<\/div>\n
\u2022 malabsorb\u0163ie\/malnutri\u0163ie<\/div>\n
\u2022 sindrom Reye<\/div>\n
\u2022 hipotiroidism<\/div>\n
\u2022 deficit de APO C-II<\/div>\n
\u2022 hiperlipidemie de tip I<\/div>\n
\u2022 alfa-beta-lipoproteinemie<\/div>\n
\u2022 eforturi<\/div>\n
\u2022 infec\u0163ii3;<\/sup>4<\/sup><\/div>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\u00a0Limite \u015fi interferen\u0163e APO A-1 <\/em><\/strong>\u00a0<\/strong><\/p>\n

\u2022 Medicamente<\/p>\n

Cre\u015fteri<\/span> <\/strong>: carbamazepina, furosemid, contraceptive orale, fenobarbital, fenitoin, prednisolon, deriva\u0163i ai acidului fibric (ex. clofibrat, gemfibrozil)2<\/sup>.<\/div>\n
Sc\u0103deri<\/strong><\/span> : lovastatin2<\/sup>.<\/div>\n

Limite \u015fi interferen\u0163e APO B <\/em><\/strong><\/p>\n

\u2022 Medicamente<\/p>\n

Cre\u015fteri<\/span>:<\/strong> amiodarona, atenolol, ciclosporina, estrogeni, furosemid, metoprolol, fenobarbital, iod radioactiv, androgeni (steroizi anabolizanti), chlortialidona, gemfibrozil, isotretinoin, levonorgestrel, contraceptive orale, simvastatin, stanozolol2<\/sup>.<\/p>\n

Sc\u0103deri<\/strong><\/span>: captopril, indometacin, interferon, ketoconazol, neomicina, niacin, nifedipin, prazosin, prednisolon, tacrolimus, colestiramina, colestipol, estrogeni (post-menopauza), deriva\u0163i ai acidului fibric (ex: clofibrat, gemfibrozil), simvastatin, lovastatin, pravastatin, ketoconazol, neomicina, niacin2<\/sup> etc.<\/p>\n

\u2022\u00a0 Interferen\u0163e analitice<\/p>\n

\u00cen cazuri foarte rare prezen\u0163a gamapatiei, \u00een special IgM (macroglobulinemia Waldenstr\u00f6m) poate determina rezultate eronate5<\/sup>.<\/p>\n

\u00a0<\/span><\/p>\n

\u0411\u0438\u0431\u043b\u0438\u043e\u0433\u0440\u0430\u0444\u0438\u044f<\/span><\/strong><\/p>\n

1. Alaupovic P. Apolipoproteins and Lipoproteins. In Atherosclerosis 13(2):141-6. 1971 Ref Type: Journal (Full)<\/span><\/div>\n
2. Frances Fischbach. Effects of the Most Commonly Used Drugs on Frequently Ordered Laboratory Tests. In A Manual of Laboratory and Diagnostic Tests. Lippincott Williams & Wilkins, USA, 8 ed. 2009, 1227.<\/span><\/div>\n
3. Frances Fischbach. Chemistry Studies. In A Manual of Laboratory and Diagnostic Tests. Lippincott Williams & Wilkins, USA, 8 ed. 2009, 455-456.<\/span><\/div>\n
4. Jacques Wallach.Boli metabolice si ereditare. In Interpretarea testelor de diagnostic. Editura Stiintelor Medicale, Romania, 7 ed. 2001, 653-752.<\/span><\/div>\n
5. Laborator Synevo. Referin\u0163ele specifice tehnologiei de lucru utilizate 2010. Ref Type: Catalog<\/span><\/div>\n
6. Laboratory Corporation of America. Directory of Services and Interpretive Guide. Apolipoproteina A-1. www.labcorp.com 2010 Ref Type: Internet Communication<\/span><\/div>\n
7. Maciejko JJ, Holmes DR, Kottke BA, et al. (1983), Apolipoprotein A-1 as a Marker of Angiographically Assessed Coronary-Artery Disease. In N Engl J Med 309(7):385-9:<\/span><\/div>\n
8. Miller NE. Association of High Density Lipoprotein Subclasses and Apolipoproteins with Ischemic Heart Disease and Coronary Atherosclerosis. In Am Heart J 113(2 ):587-97. 1987. Ref Type: Journal (Full).<\/span><\/div>","protected":false},"excerpt":{"rendered":"

\u0410\u043f\u043e\u043b\u0438\u043f\u043e\u043f\u0440\u043e\u0442\u0435\u0438\u043d\u044b \u2013 \u044d\u0442\u043e \u0431\u0435\u043b\u043a\u043e\u0432\u0430\u044f \u0447\u0430\u0441\u0442\u044c \u043b\u0438\u043f\u0438\u0434\u043d\u044b\u0445 \u043a\u043e\u043c\u043f\u043b\u0435\u043a\u0441\u043e\u0432, \u043f\u043e\u0441\u0440\u0435\u0434\u0441\u0442\u0432\u043e\u043c \u043a\u043e\u0442\u043e\u0440\u044b\u0445 \u043b\u0438\u043f\u0438\u0434\u044b \u043f\u0435\u0440\u0435\u043d\u043e\u0441\u044f\u0442\u0441\u044f \u043a\u0440\u043e\u0432\u044c\u044e \u0432 \u043e\u0440\u0433\u0430\u043d\u0438\u0437\u043c\u0435. \u041e\u043d\u0438 \u043e\u0431\u0435\u0441\u043f\u0435\u0447\u0438\u0432\u0430\u044e\u0442 \u0441\u0432\u043e\u0439\u0441\u0442\u0432\u0430 \u0440\u0430\u0441\u0442\u0432\u043e\u0440\u0438\u043c\u043e\u0441\u0442\u0438, \u043f\u043e\u043a\u0440\u044b\u0432\u0430\u044f \u0441\u043e\u0431\u043e\u0439 \u043d\u0435\u0440\u0430\u0441\u0442\u0432\u043e\u0440\u0438\u043c\u043e\u0435 \u0432 \u0432\u043e\u0434\u0435 \u044f\u0434\u0440\u043e \u0438\u0437 \u0445\u043e\u043b\u0435\u0441\u0442\u0435\u0440\u043e\u043b\u0430.<\/p>\n

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\u0414\u043b\u044f \u0447\u0435\u0433\u043e \u0438\u0441\u043f\u043e\u043b\u044c\u0437\u0443\u0435\u0442\u0441\u044f \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u0435?<\/strong><\/p>\n

    \n
  1. \u0414\u043b\u044f \u043e\u0446\u0435\u043d\u043a\u0438 \u0440\u0438\u0441\u043a\u0430 \u0440\u0430\u0437\u0432\u0438\u0442\u0438\u044f \u0441\u0435\u0440\u0434\u0435\u0447\u043d\u043e-\u0441\u043e\u0441\u0443\u0434\u0438\u0441\u0442\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439 \u0438 \u0438\u0445 \u043e\u0441\u043b\u043e\u0436\u043d\u0435\u043d\u0438\u0439.<\/li>\n
  2. \u0414\u043b\u044f \u0440\u0430\u0441\u0447\u0435\u0442\u0430 \u0430\u043f\u043e\u043b\u0438\u043f\u043e\u043f\u0440\u043e\u0442\u0435\u0438\u043d \u0412 \/ \u0430\u043f\u043e\u043b\u0438\u043f\u043e\u043f\u0440\u043e\u0442\u0435\u0438\u043d \u04101 \u2013 \u043a\u043e\u044d\u0444\u0444\u0438\u0446\u0438\u0435\u043d\u0442\u0430, \u043a\u043e\u0442\u043e\u0440\u044b\u0439 \u0438\u043d\u043e\u0433\u0434\u0430 \u0438\u0441\u043f\u043e\u043b\u044c\u0437\u0443\u0435\u0442\u0441\u044f \u0432\u043c\u0435\u0441\u0442\u043e \u043a\u043e\u044d\u0444\u0444\u0438\u0446\u0438\u0435\u043d\u0442\u0430 \u0430\u0442\u0435\u0440\u043e\u0433\u0435\u043d\u043d\u043e\u0441\u0442\u0438 \u043e\u043f\u044f\u0442\u044c \u0436\u0435 \u0434\u043b\u044f \u043e\u0446\u0435\u043d\u043a\u0438 \u0440\u0438\u0441\u043a\u0430 \u0440\u0430\u0437\u0432\u0438\u0442\u0438\u044f \u0441\u0435\u0440\u0434\u0435\u0447\u043d\u043e-\u0441\u043e\u0441\u0443\u0434\u0438\u0441\u0442\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439 (\u0432\u043c\u0435\u0441\u0442\u0435 \u0441 \u0442\u0435\u0441\u0442\u043e\u043c \u043d\u0430 \u0430\u043f\u043e\u043b\u0438\u043f\u043e\u043f\u0440\u043e\u0442\u0435\u0438\u043d \u0412).<\/li>\n<\/ol>\n

    \u041a\u043e\u0433\u0434\u0430 \u043d\u0430\u0437\u043d\u0430\u0447\u0430\u0435\u0442\u0441\u044f \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u0435?<\/strong><\/p>\n

      \n
    1. \u0412 \u0441\u043b\u0443\u0447\u0430\u0435 \u0432\u044b\u044f\u0432\u043b\u0435\u043d\u0438\u044f \u043f\u043e\u0432\u044b\u0448\u0435\u043d\u043d\u043e\u0433\u043e \u0443\u0440\u043e\u0432\u043d\u044f \u043e\u0431\u0449\u0435\u0433\u043e \u0445\u043e\u043b\u0435\u0441\u0442\u0435\u0440\u0438\u043d\u0430.<\/li>\n
    2. \u0415\u0441\u043b\u0438 \u0443 \u0440\u043e\u0434\u0441\u0442\u0432\u0435\u043d\u043d\u0438\u043a\u043e\u0432 \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u0430 \u0431\u044b\u043b\u0438 \u0441\u043b\u0443\u0447\u0430\u0438 \u0441\u0435\u0440\u0434\u0435\u0447\u043d\u043e-\u0441\u043e\u0441\u0443\u0434\u0438\u0441\u0442\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439 \u0438 \u0438\u0445 \u043e\u0441\u043b\u043e\u0436\u043d\u0435\u043d\u0438\u0439 \u0432 \u043c\u043e\u043b\u043e\u0434\u043e\u043c \u0432\u043e\u0437\u0440\u0430\u0441\u0442\u0435.<\/li>\n
    3. \u0415\u0441\u043b\u0438 \u0435\u0441\u0442\u044c \u043f\u043e\u0434\u043e\u0437\u0440\u0435\u043d\u0438\u0435 \u043d\u0430 \u0433\u0435\u043d\u0435\u0442\u0438\u0447\u0435\u0441\u043a\u0438 \u043e\u0431\u0443\u0441\u043b\u043e\u0432\u043b\u0435\u043d\u043d\u044b\u0439 \u0434\u0435\u0444\u0438\u0446\u0438\u0442 \u0430\u043f\u043e\u043b\u0438\u043f\u043e\u043f\u0440\u043e\u0442\u0435\u0438\u043d\u0430 \u0410.<\/li>\n
    4. \u041f\u0440\u0438 \u043f\u043e\u0434\u043e\u0437\u0440\u0435\u043d\u0438\u0438 \u043d\u0430 \u0442\u043e, \u0447\u0442\u043e \u0433\u0438\u043f\u0435\u0440\u043b\u0438\u043f\u0438\u0434\u0435\u043c\u0438\u044f \u0443 \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u0430 \u0432\u044b\u0437\u0432\u0430\u043d\u0430 \u0434\u0435\u0444\u0438\u0446\u0438\u0442\u043e\u043c \u0430\u043f\u043e\u043b\u0438\u043f\u043e\u043f\u0440\u043e\u0442\u0435\u0438\u043d\u0430 \u04101.<\/li>\n
    5. \u0415\u0441\u043b\u0438 \u043f\u0440\u0435\u0434\u044b\u0434\u0443\u0449\u0438\u0435 \u0440\u0435\u0437\u0443\u043b\u044c\u0442\u0430\u0442\u044b \u0430\u043d\u0430\u043b\u0438\u0437\u043e\u0432 \u043f\u043e\u043a\u0430\u0437\u0430\u043b\u0438 \u0432\u044b\u0441\u043e\u043a\u0438\u0439 \u0440\u0438\u0441\u043a \u0440\u0430\u0437\u0432\u0438\u0442\u0438\u044f \u0441\u0435\u0440\u0434\u0435\u0447\u043d\u043e-\u0441\u043e\u0441\u0443\u0434\u0438\u0441\u0442\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439, \u0435\u0441\u043b\u0438 \u043f\u0430\u0446\u0438\u0435\u043d\u0442 \u0441\u043e\u0431\u043b\u044e\u0434\u0430\u0435\u0442 \u0434\u0438\u0435\u0442\u0443 \u0441 \u043e\u0433\u0440\u0430\u043d\u0438\u0447\u0435\u043d\u0438\u0435\u043c \u0436\u0438\u0432\u043e\u0442\u043d\u044b\u0445 \u0436\u0438\u0440\u043e\u0432 \u0438\/\u0438\u043b\u0438 \u043f\u0440\u0438\u043d\u0438\u043c\u0430\u0435\u0442 \u043b\u0438\u043f\u0438\u0434\u0441\u043d\u0438\u0436\u0430\u044e\u0449\u0438\u0435 \u043f\u0440\u0435\u043f\u0430\u0440\u0430\u0442\u044b \u2013 \u0441\u0442\u0430\u0442\u0438\u043d\u044b (\u0447\u0442\u043e\u0431\u044b \u043e\u043f\u0440\u0435\u0434\u0435\u043b\u0438\u0442\u044c, \u0434\u043e\u0441\u0442\u0438\u0433\u0430\u0435\u0442\u0441\u044f \u043b\u0438 \u0446\u0435\u043b\u0435\u0432\u043e\u0439 \u0443\u0440\u043e\u0432\u0435\u043d\u044c \u0437\u043d\u0430\u0447\u0435\u043d\u0438\u044f \u043b\u0438\u043f\u0438\u0434\u043e\u0432 \u0438 \u0441\u043d\u0438\u0436\u0430\u0435\u0442\u0441\u044f \u043b\u0438 \u0440\u0438\u0441\u043a \u0441\u0435\u0440\u0434\u0435\u0447\u043d\u043e-\u0441\u043e\u0441\u0443\u0434\u0438\u0441\u0442\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439).<\/li>\n<\/ol>\n

      \u041a \u0444\u0430\u043a\u0442\u043e\u0440\u0430\u043c \u0440\u0438\u0441\u043a\u0430 \u0440\u0430\u0437\u0432\u0438\u0442\u0438\u044f \u0441\u0435\u0440\u0434\u0435\u0447\u043d\u043e-\u0441\u043e\u0441\u0443\u0434\u0438\u0441\u0442\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439 \u043e\u0442\u043d\u043e\u0441\u044f\u0442\u0441\u044f<\/strong>:<\/p>\n

        \n
      • \u043a\u0443\u0440\u0435\u043d\u0438\u0435,<\/li>\n
      • \u0432\u043e\u0437\u0440\u0430\u0441\u0442 (\u0434\u043b\u044f \u043c\u0443\u0436\u0447\u0438\u043d \u0431\u043e\u043b\u0435\u0435 45 \u043b\u0435\u0442, \u0434\u043b\u044f \u0436\u0435\u043d\u0449\u0438\u043d \u0431\u043e\u043b\u0435\u0435 55 \u043b\u0435\u0442),<\/li>\n
      • \u043f\u043e\u0432\u044b\u0448\u0435\u043d\u0438\u0435 \u0430\u0440\u0442\u0435\u0440\u0438\u0430\u043b\u044c\u043d\u043e\u0433\u043e \u0434\u0430\u0432\u043b\u0435\u043d\u0438\u044f (140\/90 \u043c\u043c. \u0440\u0442. \u0441\u0442. \u0438 \u0432\u044b\u0448\u0435),<\/li>\n
      • \u043f\u043e\u0432\u044b\u0448\u0435\u043d\u043d\u044b\u0439 \u0445\u043e\u043b\u0435\u0441\u0442\u0435\u0440\u043e\u043b \u0438\u043b\u0438 \u0441\u0435\u0440\u0434\u0435\u0447\u043d\u043e-\u0441\u043e\u0441\u0443\u0434\u0438\u0441\u0442\u044b\u0435 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u044f \u0443 \u0434\u0440\u0443\u0433\u0438\u0445 \u0447\u043b\u0435\u043d\u043e\u0432 \u0441\u0435\u043c\u044c\u0438 (\u0438\u043d\u0444\u0430\u0440\u043a\u0442 \u0438\u043b\u0438 \u0438\u043d\u0441\u0443\u043b\u044c\u0442 \u0443 \u0431\u043b\u0438\u0436\u0430\u0439\u0448\u0435\u0433\u043e \u0440\u043e\u0434\u0441\u0442\u0432\u0435\u043d\u043d\u0438\u043a\u0430 \u043c\u0443\u0436\u0441\u043a\u043e\u0433\u043e \u043f\u043e\u043b\u0430 \u043c\u043e\u043b\u043e\u0436\u0435 55 \u043b\u0435\u0442, \u0436\u0435\u043d\u0441\u043a\u043e\u0433\u043e \u2013 \u043c\u043e\u043b\u043e\u0436\u0435 65 \u043b\u0435\u0442),<\/li>\n
      • \u0438\u0448\u0435\u043c\u0438\u0447\u0435\u0441\u043a\u0430\u044f \u0431\u043e\u043b\u0435\u0437\u043d\u044c \u0441\u0435\u0440\u0434\u0446\u0430, \u043f\u0435\u0440\u0435\u043d\u0435\u0441\u0435\u043d\u043d\u044b\u0439 \u0438\u043d\u0444\u0430\u0440\u043a\u0442 \u0441\u0435\u0440\u0434\u0435\u0447\u043d\u043e\u0439 \u043c\u044b\u0448\u0446\u044b \u0438\u043b\u0438 \u0438\u043d\u0441\u0443\u043b\u044c\u0442,<\/li>\n
      • \u0441\u0430\u0445\u0430\u0440\u043d\u044b\u0439 \u0434\u0438\u0430\u0431\u0435\u0442,<\/li>\n
      • \u0438\u0437\u0431\u044b\u0442\u043e\u0447\u043d\u0430\u044f \u043c\u0430\u0441\u0441\u0430 \u0442\u0435\u043b\u0430,<\/li>\n
      • \u0437\u043b\u043e\u0443\u043f\u043e\u0442\u0440\u0435\u0431\u043b\u0435\u043d\u0438\u0435 \u0430\u043b\u043a\u043e\u0433\u043e\u043b\u0435\u043c,<\/li>\n
      • \u043f\u0440\u0438\u0435\u043c \u0431\u043e\u043b\u044c\u0448\u043e\u0433\u043e \u043a\u043e\u043b\u0438\u0447\u0435\u0441\u0442\u0432\u0430 \u043f\u0438\u0449\u0438, \u0441\u043e\u0434\u0435\u0440\u0436\u0430\u0449\u0435\u0439 \u0436\u0438\u0432\u043e\u0442\u043d\u044b\u0435 \u0436\u0438\u0440\u044b,<\/li>\n
      • \u043d\u0438\u0437\u043a\u0430\u044f \u0444\u0438\u0437\u0438\u0447\u0435\u0441\u043a\u0430\u044f \u0430\u043a\u0442\u0438\u0432\u043d\u043e\u0441\u0442\u044c.<\/li>\n<\/ul>\n

        \u041a\u0430\u043a \u043f\u0440\u0430\u0432\u0438\u043b\u044c\u043d\u043e \u043f\u043e\u0434\u0433\u043e\u0442\u043e\u0432\u0438\u0442\u044c\u0441\u044f \u043a \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u044e?<\/strong><\/p>\n

          \n
        • \u041d\u0435 \u043f\u0440\u0438\u043d\u0438\u043c\u0430\u0442\u044c \u043f\u0438\u0449\u0443 \u0432 \u0442\u0435\u0447\u0435\u043d\u0438\u0435 12 \u0447\u0430\u0441\u043e\u0432 \u043f\u0435\u0440\u0435\u0434 \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u0435\u043c.<\/li>\n
        • \u0418\u0441\u043a\u043b\u044e\u0447\u0438\u0442\u044c \u0444\u0438\u0437\u0438\u0447\u0435\u0441\u043a\u043e\u0435 \u0438 \u044d\u043c\u043e\u0446\u0438\u043e\u043d\u0430\u043b\u044c\u043d\u043e\u0435 \u043f\u0435\u0440\u0435\u043d\u0430\u043f\u0440\u044f\u0436\u0435\u043d\u0438\u0435 \u0437\u0430 30 \u043c\u0438\u043d\u0443\u0442 \u0434\u043e \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u044f.<\/li>\n
        • \u041d\u0435 \u043a\u0443\u0440\u0438\u0442\u044c \u0432 \u0442\u0435\u0447\u0435\u043d\u0438\u0435 30 \u043c\u0438\u043d\u0443\u0442 \u0434\u043e \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u044f.<\/li>\n<\/ul>","protected":false},"featured_media":0,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[954,953],"product_tag":[],"class_list":{"0":"post-9166","1":"product","2":"type-product","3":"status-publish","5":"product_cat-proteine-specifice-in-ser-si-urina","6":"product_cat-teste-de-biochimie","8":"first","9":"instock","10":"sold-individually","11":"shipping-taxable","12":"purchasable","13":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/product\/9166","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/comments?post=9166"}],"wp:attachment":[{"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/media?parent=9166"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/product_brand?post=9166"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/product_cat?post=9166"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/product_tag?post=9166"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}