{"id":9135,"date":"2020-04-23T03:29:07","date_gmt":"2020-04-23T01:29:07","guid":{"rendered":"https:\/\/www.synevo.ro\/product\/anti-hcv\/"},"modified":"2026-02-18T23:34:17","modified_gmt":"2026-02-18T21:34:17","slug":"anti-hcv","status":"publish","type":"product","link":"https:\/\/old.synevo.md\/ru\/shop\/anti-hcv\/","title":{"rendered":"Anti-HBs (\u0430\u043d\u0442\u0438\u0442\u0435\u043b\u0430 \u043a HBs-\u0430\u043d\u0442\u0438\u0433\u0435\u043d\u0443 \u0432\u0438\u0440\u0443\u0441\u0430 \u0433\u0435\u043f\u0430\u0442\u0438\u0442\u0430 B)"},"content":{"rendered":"

\u041e\u0431\u0449\u0430\u044f \u0438\u043d\u0444\u043e\u0440\u043c\u0430\u0446\u0438\u044f<\/em><\/strong><\/span><\/p>\n

Virusul hepatitei C (VHC) este r\u0103spunz\u0103tor de\u00a0aproximativ 20% din hepatitele acute, 60-70 % din hepatitele cronice \u015fi aproximativ 30% din cirozele \u015fi cancerele hepatice.<\/span><\/p>\n

VHC, depistat \u00een 1989, este un virus ARN din genul Flavivirus<\/em>, familia Togaviridae<\/em>, cu dimensiuni \u00eentre 40-60 nm \u015fi cu un con\u0163inut preponderent lipidic. Exist\u0103 6 genotipuri majore \u015fi 50 de serotipuri de VHC. Cunoa\u015fterea genotipului sau serotipului (anticorpii specifici genotipului) de VHC este util\u0103 \u00een recomandarea \u015fi conducerea tratamentului. VHC este transmis prin contactul cu s\u00e2nge sau produse de s\u00e2nge infectat: transfuzii, folosirea acelor \u015fi seringilor de la o persoan\u0103 la alta, f\u0103r\u0103 sterilizare sau insuficient sterilizate, tatuarea corpului, vaccinarea cu echipament nesterilizat, folosirea\u00a0\u00een comun a periu\u0163ei de din\u0163i, aparatului de b\u0103rbierit, pensetei, trusei de manichiur\u0103. Este prezent \u015fi\u00a0\u00een medii biologice (saliv\u0103, lapte, secre\u0163ii vaginale, sperm\u0103 etc.), dar\u00a0\u00een concentra\u0163ie mai mic\u0103 dec\u00e2t virusul B. Se poate transmite \u015fi de la mam\u0103 la f\u0103t2;5<\/sup>. Rata de transmisie vertical\u0103 la gravidele cu anti-HCV pozitiv a fost estimat\u0103 la 2.7-4.4%, aceast\u0103 rat\u0103 ating\u00e2nd valori de 5.4-8.6% la gravidele care au coinfec\u0163ie VHC \u2013 HIV1<\/sup>.<\/span><\/p>\n

Este bine de \u015ftiut faptul c\u0103 virusul nu se transmite prin folosirea \u00een comun a veselei, piscinelor \u015fi toaletelor2<\/sup>. <\/span>Aproximativ 85% din formele acute se cronicizeaz\u0103.<\/span><\/p>\n

Dintre purt\u0103torii cronici, cu sau f\u0103r\u0103 valori serice anormale de ALT,<\/span><\/p>\n

\u2022\u00a0 ~ 15% se vindec\u0103;<\/span><\/div>\n
\u2022\u00a0 ~ 70% dezvolt\u0103 hepatit\u0103 cronic\u0103 (interval mediu 10 ani);<\/span><\/div>\n
\u2022\u00a0 ~ 10-20% dezvolt\u0103 ciroz\u0103 (interval mediu 20 ani);<\/span><\/div>\n
\u2022\u00a0 ~ 50% mor din cauza infec\u0163iei cu VHC.<\/span><\/div>\n

Carcinomul hepatocelular poate ap\u0103rea la cca. 20% din pacien\u0163ii cu ciroz\u0103 (interval mediu 30 ani) \u015fi la 1-5% din cei infecta\u0163i cu VHC5<\/sup>.<\/span><\/p>\n

Testele diagnostice pentru depistarea infec\u0163iei cu VHC sunt de 2 categorii:<\/span><\/p>\n

\u00a0 I \u2013 teste serologice pentru depistarea anticorpilor;<\/span><\/div>\n
II \u2013 teste moleculare pentru detectarea particulelor virale.<\/span><\/div>\n

Debutul este insidios, virusul\u00a0 fiind numit \u015fi \u201cbomb\u0103 cu efect \u00eent\u00e2rziat\u201d. <\/span>\u201cFereastra serologic\u0103\u201d \u00eentre infec\u0163ia VHC \u015fi detectarea anti-HCV variaz\u0103 de la pacient la pacient.<\/span><\/p>\n

Cu testele serologice curente anticorpii se depisteaz\u0103 \u00een medie la 7-8 s\u0103pt\u0103m\u00e2ni de la debutul infec\u0163iei. \u00cen cazul eradic\u0103rii spontane a infec\u0163iei, anti-HCV pot s\u0103 persiste toat\u0103 via\u0163a sau s\u0103 scad\u0103 treptat p\u00e2n\u0103 la dispari\u0163ie \u00een c\u00e2\u0163iva ani. La pacien\u0163ii cu infec\u0163ie cronic\u0103 anti-HCV persist\u0103 indefinit. \u00cen popula\u0163ia cu risc sc\u0103zut procentul de persoane care scap\u0103 diagnostic\u0103rii este de 0.5-1%.<\/span><\/p>\n

Rezultatele pozitive trebuie confirmate printr-o analiz\u0103 suplimentar\u0103 \u2013 RIBA (recombinant immunoblot assay) care s\u0103 indice rectivitatea fa\u0163\u0103 de 2 antigene virale.<\/span><\/p>\n

Odat\u0103 cu \u00eembun\u0103t\u0103\u0163irea testelor screening \u015fi a tehnicilor moleculare, confirmarea prin RIBA devine din ce \u00een ce mai pu\u0163in necesar\u0103 (excep\u0163ie b\u0103ncile de s\u00e2nge).<\/span><\/p>\n

Testarea pentru ARN-VHC (prin PCR) confirm\u0103 diagnosticul \u015fi cuantific\u0103 num\u0103rul de copii virale \u00een s\u00e2nge (viremie). Aproape to\u0163i pacien\u0163ii cu infec\u0163ie cronic\u0103 au ARN-VHC detectabil\u00a0\u00een s\u00e2nge4;5<\/sup>.<\/span><\/p>\n

Recomand\u0103ri pentru determinarea anti-HCV<\/em><\/strong><\/span><\/p>\n

\u2022\u00a0 diagnosticul de infec\u0163ie acut\u0103\/cronic\u0103 sau \u00een antecedente cu virusul hepatitei C;<\/span><\/div>\n
\u2022\u00a0 screening-ul produselor de s\u00e2nge \u015fi al donatorilor;<\/span><\/div>\n
\u2022\u00a0 screening-ul prenatal, \u00een scopul prevenirii transmiterii infec\u0163iei la f\u0103t1;4<\/sup>.<\/span><\/div>\n

Preg\u0103tire pacient <\/em><\/strong>\u2013 \u00e0 jeun (pe nem\u00e2ncate)3<\/sup>.<\/span><\/p>\n

Specimen recoltat <\/em><\/strong>\u2013 s\u00e2nge venos3<\/sup>.<\/span><\/p>\n

Recipient de recoltare <\/em><\/strong>\u2013 vacutainer f\u0103r\u0103 anticoagulant cu\/f\u0103r\u0103 gel separator3<\/sup>.<\/span><\/p>\n

Prelucrare necesar\u0103 dup\u0103 recoltare <\/em><\/strong>\u2013 se separ\u0103 serul prin centrifugare. Se lucreaz\u0103 imediat, dac\u0103 acest lucru nu este posibil, serul se p\u0103streaz\u0103 la 2-8\u00b0C sau la -20\u00b0C3<\/sup>.<\/span><\/p>\n

Volum prob\u0103<\/em><\/strong> \u2013 minim 0.5 mL ser3<\/sup><\/span><\/p>\n

Cauze de respingere a probei <\/em><\/strong>\u2013 specimen hemolizat; specimen expus la temperaturi ridicate; specimen contaminat bacterian; specimen care con\u0163ine azida de sodiu3<\/sup>.<\/span><\/p>\n

Stabilitate prob\u0103 <\/em><\/strong>\u2013 serul este stabil 5 zile<\/em> la 2-8\u00b0C; timp \u00eendelungat<\/em> la -20\u00b0C; evita\u0163i decongelarea\/recongelarea3<\/sup>.<\/span><\/p>\n

Metod\u0103 <\/em><\/strong>- imunochimic\u0103 cu detec\u0163ie prin electrochemiluminiscen\u0163\u0103 (ECLIA)<\/span>.<\/span><\/p>\n

Testul utilizeaz\u0103 antigene derivate dintr-o protein\u0103 structural\u0103 (core) \u015fi 2 proteine non-structurale (NS3 si NS4) ale VHC; NS3 \u2013 antigenul imunodominant VHC \u2013 este ob\u0163inut prin recombinare genetic\u0103 \u015fi este \u201cre\u00eenf\u0103\u015furat\u201d pentru a se ob\u0163ine o activitate imunologic\u0103 crescut\u0103; testul prezint\u0103 o sensibilitate mare fa\u0163\u0103 de toate cele 6 genotipuri provenite din arii geografice diferite3<\/sup>.<\/span><\/p>\n

Valori de referin\u0163\u0103 <\/em><\/strong>\u2013 anti-HCV negativ3<\/sup>.<\/span><\/p>\n

Limite \u015fi interferen\u0163e<\/em><\/strong><\/span><\/p>\n

Rezultate fals negative pot fi \u00eent\u00e2lnite la imunodeprima\u0163i (HIV pozitivi), pacien\u0163i cu insuficien\u0163\u0103 renal\u0103, crioglobulinemie mixt\u0103 esen\u0163ial\u0103, \u00een caz de congel\u0103ri \u015fi decongel\u0103ri repetate sau depozitare prelungit\u0103 a e\u015fantioanelor de s\u00e2nge.<\/span><\/p>\n

Rezultate fals pozitive, chiar \u015fi pentru testele de genera\u0163ia a 3-a, pot s\u0103 apar\u0103 \u00een boli autoimune (80% dintre cazurile de hepatit\u0103 cronic\u0103 activ\u0103 autoimun\u0103), poliarterit\u0103 nodoas\u0103, prezen\u0163a de factor reumatoid, hipergamaglobulinemie, paraproteinemie, transfer pasiv de anticorpi, anticorpi antisuperoxid dismutaz\u0103 (o enzim\u0103 uman\u0103 utilizat\u0103 \u00een procesul de clonare)5<\/sup>.<\/span><\/p>\n

Detectarea anticorpilor anti-HCV nu permite distinc\u0163ia dintre o infec\u0163ie curent\u0103 \u015fi o infec\u0163ie \u00een antecedente. Pentru confirmarea diagnosticului de infec\u0163ie activ\u0103 cu virusul hepatitei C este necesar\u0103 efectuarea ARN-VHC4<\/sup>.<\/span><\/p>\n

\u00centr-un procent redus de cazuri se poate ob\u0163ine un rezultat slab pozitiv pentru anti-HCV<\/span> (analizorul indic\u0103 o valoare apropiat\u0103 de valoarea cut-off a pozitivit\u0103\u0163ii); \u00een aceste cazuri este folosit\u0103 \u015fi o metod\u0103 alternativ\u0103 de testare (ELISA). Laboratorul va comunica astfel de situa\u0163ii, cu recomandarea de a se verifica specificitatea anticorpilor anti-HCV prin testul de confirmare Western blot3<\/sup>.<\/span><\/p>\n

\u00a0<\/span><\/p>\n

\u0411\u0438\u0431\u043b\u0438\u043e\u0433\u0440\u0430\u0444\u0438\u044f<\/span><\/strong><\/div>\n
<\/div>\n
1. Ann M. Gronowski. Screening and Diagnosis of Congenital Infections. In Handbook of Clinical Laboratory Testing During Pregnancy. Totowa, NJ: Humana Press ed. 2004, 257.<\/span><\/div>\n
2. Georg M. Lauer, Bruce D.Walker. Hepatitis C Virus Infection. In N Engl J Med 345, 41-50. 2001. Ref Type: Journal (Full).<\/span><\/div>\n
3. Laborator Synevo. Referin\u0163ele specifice tehnologiei de lucru utilizate 2010. Ref Type: Catalog.<\/span><\/div>\n
4. Lothar Thomas. Hepatitis C. In Clinical Laboratory Diagnostics \u2013 Use and Assessment of Clinical Laboratory Results. TH-Books Verlagsgesellschaft mbH, Frankfurt \/Main, Germany, 1 Ed., 1998, 1273-1276.<\/span><\/div>\n
5. Wallach J. Afec\u0163iuni hepatobiliare \u015fi pancreatice. \u00cen Interpretarea testelor de diagnostic. Editura Stiin\u0163elor Medicale, Rom\u00e2nia, Ed. 7, 2001, 316-323.<\/span><\/div>","protected":false},"excerpt":{"rendered":"

Anti-HBs (\u0430\u043d\u0442\u0438\u0442\u0435\u043b\u0430 \u043a HBs-\u0430\u043d\u0442\u0438\u0433\u0435\u043d\u0443 \u0432\u0438\u0440\u0443\u0441\u0430 \u0433\u0435\u043f\u0430\u0442\u0438\u0442\u0430 B) \u2013 \u043f\u043e\u043a\u0430\u0437\u0430\u0442\u0435\u043b\u044c \u043d\u0430\u043b\u0438\u0447\u0438\u044f \u0437\u0430\u0449\u0438\u0442\u043d\u043e\u0433\u043e \u0438\u043c\u043c\u0443\u043d\u0438\u0442\u0435\u0442\u0430 \u043f\u0440\u043e\u0442\u0438\u0432 \u0432\u0438\u0440\u0443\u0441\u0430 \u0433\u0435\u043f\u0430\u0442\u0438\u0442\u0430 \u0412.<\/p>\n

Anti-HBs-\u0430\u043d\u0442\u0438\u0442\u0435\u043b\u0430 \u043f\u043e\u044f\u0432\u043b\u044f\u044e\u0442\u0441\u044f \u0432 \u0444\u0430\u0437\u0435 \u0432\u044b\u0437\u0434\u043e\u0440\u043e\u0432\u043b\u0435\u043d\u0438\u044f \u043f\u043e\u0441\u043b\u0435 \u043e\u0441\u0442\u0440\u043e\u0433\u043e \u0433\u0435\u043f\u0430\u0442\u0438\u0442\u0430 \u0412, \u043e\u0431\u044b\u0447\u043d\u043e \u0447\u0435\u0440\u0435\u0437 3-4 \u043c\u0435\u0441\u044f\u0446\u0430 \u043f\u043e\u0441\u043b\u0435 \u044d\u043b\u0438\u043c\u0438\u043d\u0430\u0446\u0438\u0438 HBsAg (\u0442\u0430\u043a \u043d\u0430\u0437\u044b\u0432\u0430\u0435\u043c\u0430\u044f \u0444\u0430\u0437\u0430 \u00ab\u043e\u043a\u043d\u0430\u00bb). \u041f\u0440\u043e\u0434\u043e\u043b\u0436\u0438\u0442\u0435\u043b\u044c\u043d\u043e\u0441\u0442\u044c \u0444\u0430\u0437\u044b \u043e\u043a\u043d\u0430 \u043c\u043e\u0436\u0435\u0442 \u0432\u0430\u0440\u044c\u0438\u0440\u043e\u0432\u0430\u0442\u044c \u043e\u0442 1 \u043c\u0435\u0441 \u0434\u043e 1 \u0433\u043e\u0434\u0430, \u0432 \u0437\u0430\u0432\u0438\u0441\u0438\u043c\u043e\u0441\u0442\u0438 \u043e\u0442 \u0441\u043e\u0441\u0442\u043e\u044f\u043d\u0438\u044f \u0438\u043c\u043c\u0443\u043d\u043d\u043e\u0439 \u0441\u0438\u0441\u0442\u0435\u043c\u044b \u0431\u043e\u043b\u044c\u043d\u043e\u0433\u043e. \u0412 \u044d\u0442\u043e\u0442 \u043f\u0435\u0440\u0438\u043e\u0434 \u00ab\u043e\u043a\u043d\u0430\u00bb \u0432\u0430\u0436\u043d\u043e \u043e\u0431\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u0442\u044c \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u0430 \u043d\u0430 anti-HBc IgM.<\/p>\n

Anti-HBs-\u0430\u043d\u0442\u0438\u0442\u0435\u043b\u0430 \u043e\u0441\u043e\u0431\u0435\u043d\u043d\u043e \u0432\u0430\u0436\u043d\u044b \u0432 \u043e\u0431\u0435\u0441\u043f\u0435\u0447\u0435\u043d\u0438\u0438 \u0438\u043c\u043c\u0443\u043d\u043d\u043e\u0439 \u0437\u0430\u0449\u0438\u0442\u044b \u043f\u0440\u043e\u0442\u0438\u0432 \u0434\u0430\u043d\u043d\u043e\u0433\u043e \u0432\u0438\u0440\u0443\u0441\u0430, \u043f\u043e\u044d\u0442\u043e\u043c\u0443 \u043a\u043e\u043b\u0438\u0447\u0435\u0441\u0442\u0432\u0435\u043d\u043d\u043e\u0435 \u043e\u043f\u0440\u0435\u0434\u0435\u043b\u0435\u043d\u0438\u0435 \u0430\u043d\u0442\u0438-HBs-\u0430\u043d\u0442\u0438\u0442\u0435\u043b \u043e\u0431\u044b\u0447\u043d\u043e \u0438\u0441\u043f\u043e\u043b\u044c\u0437\u0443\u044e\u0442 \u0432 \u043a\u043e\u043d\u0442\u0440\u043e\u043b\u0435 \u044d\u0444\u0444\u0435\u043a\u0442\u0438\u0432\u043d\u043e\u0441\u0442\u0438 \u0438\u043c\u043c\u0443\u043d\u0438\u0442\u0435\u0442\u0430 \u043f\u0440\u0438 \u0432\u0430\u043a\u0446\u0438\u043d\u0430\u0446\u0438\u0438 \u043f\u0440\u043e\u0442\u0438\u0432 \u0433\u0435\u043f\u0430\u0442\u0438\u0442\u0430 \u0412. \u0421\u043e \u0432\u0440\u0435\u043c\u0435\u043d\u0435\u043c, \u0442\u0438\u0442\u0440 \u0430\u043d\u0442\u0438\u0442\u0435\u043b \u0441\u043d\u0438\u0436\u0430\u0435\u0442\u0441\u044f \u0432\u043f\u043b\u043e\u0442\u044c \u0434\u043e \u043d\u0435\u043e\u0431\u043d\u0430\u0440\u0443\u0436\u0435\u043d\u0438\u044f. \u0418\u043d\u043e\u0433\u0434\u0430 \u0432\u043e\u0437\u043c\u043e\u0436\u043d\u043e \u043f\u043e\u0436\u0438\u0437\u043d\u0435\u043d\u043d\u0430\u044f \u0446\u0438\u0440\u043a\u0443\u043b\u044f\u0446\u0438\u044f anti-HBs \u0430\u043d\u0442\u0438\u0442\u0435\u043b. \u041f\u043e\u044f\u0432\u043b\u0435\u043d\u0438\u0435 \u0430\u043d\u0442\u0438-HBs \u043d\u0430 \u0444\u043e\u043d\u0435 \u043a\u043b\u0438\u043d\u0438\u0447\u0435\u0441\u043a\u043e\u0433\u043e \u0443\u043b\u0443\u0447\u0448\u0435\u043d\u0438\u044f \u0443 \u0431\u043e\u043b\u044c\u043d\u043e\u0433\u043e \u0433\u0435\u043f\u0430\u0442\u0438\u0442\u043e\u043c \u0412 \u0438 \u0438\u0441\u0447\u0435\u0437\u043d\u043e\u0432\u0435\u043d\u0438\u0435 HBsAg \u044f\u0432\u043b\u044f\u0435\u0442\u0441\u044f \u0445\u043e\u0440\u043e\u0448\u0438\u043c \u043f\u0440\u043e\u0433\u043d\u043e\u0441\u0442\u0438\u0447\u0435\u0441\u043a\u0438\u043c \u043f\u0440\u0438\u0437\u043d\u0430\u043a\u043e\u043c, \u0438 \u043f\u043e\u043a\u0430\u0437\u0430\u0442\u0435\u043b\u0435\u043c \u0432\u044b\u0437\u0434\u043e\u0440\u043e\u0432\u043b\u0435\u043d\u0438\u044f.<\/p>\n

\u041f\u0440\u0438 \u0445\u0440\u043e\u043d\u0438\u0447\u0435\u0441\u043a\u043e\u043c \u0442\u0435\u0447\u0435\u043d\u0438\u0438 \u0433\u0435\u043f\u0430\u0442\u0438\u0442\u0430 \u0412 \u0432\u043e\u0437\u043c\u043e\u0436\u043d\u043e \u043f\u0430\u0440\u0430\u043b\u043b\u0435\u043b\u044c\u043d\u043e\u0435 \u043e\u043f\u0440\u0435\u0434\u0435\u043b\u0435\u043d\u0438\u0435 \u043f\u043e\u0432\u0435\u0440\u0445\u043d\u043e\u0441\u0442\u043d\u043e\u0433\u043e \u0430\u043d\u0442\u0438\u0433\u0435\u043d\u0430 \u0438 \u0430\u043d\u0442\u0438\u0442\u0435\u043b \u043a \u043d\u0435\u043c\u0443. \u041e\u0431\u043d\u0430\u0440\u0443\u0436\u0435\u043d\u0438\u0435 \u0430\u043d\u0442\u0438-HBs \u0432 \u043e\u0441\u0442\u0440\u043e\u0439 \u0444\u0430\u0437\u0435 \u0433\u0435\u043f\u0430\u0442\u0438\u0442\u0430 \u0412 \u043f\u0430\u0440\u0430\u043b\u043b\u0435\u043b\u044c\u043d\u043e \u0441 HBsAg \u0441\u0432\u0438\u0434\u0435\u0442\u0435\u043b\u044c\u0441\u0442\u0432\u0443\u0435\u0442 \u043e \u043d\u0435\u0431\u043b\u0430\u0433\u043e\u043f\u0440\u0438\u044f\u0442\u043d\u043e\u043c \u043f\u0440\u043e\u0433\u043d\u043e\u0437\u0435 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u044f.<\/p>\n

\u041f\u043e\u043a\u0430\u0437\u0430\u043d\u0438\u044f \u043a \u043d\u0430\u0437\u043d\u0430\u0447\u0435\u043d\u0438\u044e \u0430\u043d\u0430\u043b\u0438\u0437\u0430:<\/p>\n

    \n
  1. \u041f\u043e\u0434\u0433\u043e\u0442\u043e\u0432\u043a\u0430 \u043a \u0432\u0430\u043a\u0446\u0438\u043d\u0430\u0446\u0438\u0438;<\/li>\n
  2. \u041f\u043e\u0434\u0442\u0432\u0435\u0440\u0436\u0434\u0435\u043d\u0438\u0435 \u044d\u0444\u0444\u0435\u043a\u0442\u0438\u0432\u043d\u043e\u0441\u0442\u0438 \u0432\u0430\u043a\u0446\u0438\u043d\u0430\u0446\u0438\u0438;<\/li>\n
  3. \u0412\u044b\u044f\u0432\u043b\u0435\u043d\u0438\u0435 HBs-\u0430\u043d\u0442\u0438\u0433\u0435\u043d\u0430;<\/li>\n
  4. \u041a\u043b\u0438\u043d\u0438\u0447\u0435\u0441\u043a\u0430\u044f \u043a\u0430\u0440\u0442\u0438\u043d\u0430 \u0432\u0438\u0440\u0443\u0441\u043d\u043e\u0433\u043e \u0433\u0435\u043f\u0430\u0442\u0438\u0442\u0430, \u0432 \u043e\u0442\u0441\u0443\u0442\u0441\u0442\u0432\u0438\u0435 \u043c\u0430\u0440\u043a\u0435\u0440\u043e\u0432 \u0434\u0440\u0443\u0433\u0438\u0445 \u0432\u0438\u0440\u0443\u0441\u043d\u044b\u0445 \u0433\u0435\u043f\u0430\u0442\u0438\u0442\u043e\u0432 \u0438 HBsAg<\/li>\n<\/ol>","protected":false},"featured_media":0,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[924],"product_tag":[],"class_list":{"0":"post-9135","1":"product","2":"type-product","3":"status-publish","5":"product_cat-markeri-virali","7":"first","8":"instock","9":"sold-individually","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/product\/9135","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/comments?post=9135"}],"wp:attachment":[{"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/media?parent=9135"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/product_brand?post=9135"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/product_cat?post=9135"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/product_tag?post=9135"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}