{"id":12105,"date":"2020-05-05T23:16:45","date_gmt":"2020-05-05T20:16:45","guid":{"rendered":"https:\/\/www.synevo.ro\/shop\/11-deoxicorticosteron\/"},"modified":"2025-02-07T12:38:02","modified_gmt":"2025-02-07T10:38:02","slug":"11-deoxicorticosteron","status":"publish","type":"product","link":"https:\/\/old.synevo.md\/ru\/shop\/11-deoxicorticosteron\/","title":{"rendered":"11-\u0414\u0435\u0437\u043e\u0301\u043a\u0441\u0438\u043a\u043e\u0301\u0440\u0442\u0438\u043a\u043e\u0441\u0442\u0435\u0440\u043e\u0301\u043d"},"content":{"rendered":"<p>Determinarea seric\u0103 a 11-Deoxicorticosteron seric este recomandat\u0103 \u00een evaluarea suspiciunii de tumor\u0103 suprarenalian\u0103 adrenocorticoida voluminoas\u0103.<\/p>\n<p>Este un hormon steroid produs de glanda suprarenala, cu activitate mineralocorticoida, fiind un precuror al aldosteronului. DOC este produs de tumorile suprarenale pure, care sunt foarte rare \u0219i de obicei voluminoase \u0219i maligne. Exista si adenoame adrenocorticoide benigne care produc DOC. Unele neoplasme suprarenale co-secreta androgeni \u0219i estrogeni \u00een plus fa\u021b\u0103 de DOC si pot provoca virilizare la femei sau feminizarea la b\u0103rba\u021bi. Prezentarea clinic\u0103 tipic\u0103 ar fi aceea a debutului relativ rapid al unei hipertensiuni arteriale marcate, asociate cu hipokaliemie \u0219i niveluri sc\u0103zute de aldosteron \u0219i renin\u0103 \u00een s\u00e2nge. Un nivel ridicat de DOC plasmatic sau tetrahidrodeoxicorticosteron urinar \u0219i o tumor\u0103 suprarenal\u0103 voluminoasa observat\u0103 la CT confirm\u0103 diagnosticul. Secre\u021bia de aldosteron este de obicei suprimat\u0103.<\/p>","protected":false},"excerpt":{"rendered":"<p>11-\u0434\u0435\u0437\u043e\u043a\u0441\u0438\u043a\u043e\u0440\u0442\u0438\u0437\u043e\u043b (\u043a\u043e\u0440\u0442\u043e\u0434\u043e\u043a\u0441\u043e\u043d, \u043a\u043e\u0440\u0442\u0435\u043a\u0441\u043e\u043b\u043e\u043d, 11-\u0434\u0435\u043e\u043a\u0441\u0438\u043a\u043e\u0440\u0442\u0438\u0437\u043e\u043b) \u2013 \u043d\u0435\u043f\u043e\u0441\u0440\u0435\u0434\u0441\u0442\u0432\u0435\u043d\u043d\u044b\u0439 \u043f\u0440\u0435\u0434\u0448\u0435\u0441\u0442\u0432\u0435\u043d\u043d\u0438\u043a \u043a\u043e\u0440\u0442\u0438\u0437\u043e\u043b\u0430. \u042d\u0442\u043e\u0442 \u0433\u043e\u0440\u043c\u043e\u043d \u043e\u0442\u043d\u043e\u0441\u0438\u0442\u0441\u044f \u043a \u0433\u043b\u044e\u043a\u043e\u043a\u043e\u0440\u0442\u0438\u043a\u043e\u0438\u0434\u0430\u043c. \u041e\u043d \u0443\u0447\u0430\u0441\u0442\u0432\u0443\u0435\u0442 \u0432 \u0442\u0435\u0445 \u0436\u0435 \u043e\u0431\u043c\u0435\u043d\u043d\u044b\u0445 \u043f\u0440\u043e\u0446\u0435\u0441\u0441\u0430\u0445, \u0447\u0442\u043e \u0438 \u043a\u043e\u0440\u0442\u0438\u0437\u043e\u043b, \u043d\u043e \u0435\u0433\u043e \u0434\u0435\u0439\u0441\u0442\u0432\u0438\u0435 \u0441\u043b\u0430\u0431\u0435\u0435. \u041c\u043e\u0436\u0435\u0442 \u043d\u0430\u043a\u0430\u043f\u043b\u0438\u0432\u0430\u0442\u044c\u0441\u044f \u0432 \u043e\u0440\u0433\u0430\u043d\u0438\u0437\u043c\u0435 \u043f\u0440\u0438 \u043d\u0435\u0434\u043e\u0441\u0442\u0430\u0442\u043e\u0447\u043d\u043e\u0441\u0442\u0438 11\u2013\u0431\u0435\u0442\u0430-\u0433\u0438\u0434\u0440\u043e\u043a\u0441\u0438\u043b\u0430\u0437\u044b (\u0432\u0440\u043e\u0436\u0434\u0435\u043d\u043d\u0430\u044f \u0433\u0438\u043f\u0435\u0440\u043f\u043b\u0430\u0437\u0438\u044f \u043d\u0430\u0434\u043f\u043e\u0447\u0435\u0447\u043d\u0438\u043a\u043e\u0432).<\/p>","protected":false},"featured_media":0,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[917],"product_tag":[],"class_list":{"0":"post-12105","1":"product","2":"type-product","3":"status-publish","5":"product_cat-markeri-suprarenalieni","7":"first","8":"instock","9":"sold-individually","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/product\/12105","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/comments?post=12105"}],"wp:attachment":[{"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/media?parent=12105"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/product_brand?post=12105"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/product_cat?post=12105"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/product_tag?post=12105"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}