{"id":10200,"date":"2020-04-23T03:59:28","date_gmt":"2020-04-23T00:59:28","guid":{"rendered":"https:\/\/www.synevo.ro\/product\/enterovirusuri-arn\/"},"modified":"2025-01-30T15:14:32","modified_gmt":"2025-01-30T13:14:32","slug":"enterovirusuri-arn","status":"publish","type":"product","link":"https:\/\/old.synevo.md\/ru\/shop\/enterovirusuri-arn\/","title":{"rendered":"\u0420\u041d\u041a-\u044d\u043d\u0442\u0435\u0440\u043e\u0432\u0438\u0440\u0443\u0441\u044b"},"content":{"rendered":"<p><strong><em>\u041e\u0431\u0449\u0430\u044f \u0438\u043d\u0444\u043e\u0440\u043c\u0430\u0446\u0438\u044f <\/em><\/strong><\/p>\n<p>Clasificarea conventionala a enterovirusurilor cuprinde virusurile <em>polio<\/em>, <em>Coxsackie<\/em> si <em>ECHO<\/em><\/p>\n<p>(enteric cytopathogenic human orphan). Intre aceste subgenuri nu exista diferente semnificative, toate determinand in mod obisnuit infectii subclinice (inaparente) ale tractului digestiv, dar si un spectru larg de alte sindroame<sup>2<\/sup>. Ca urmare a strategiilor eficiente de vaccinare, virusurile polio salbatice 1-3 circula numai intr-un numar restrans de tari in curs de dezvoltare<sup>3<\/sup>.<\/p>\n<p>La randul lor, virusurile non-polio includ:<\/p>\n<p style=\"padding-left: 30px;\">-<span style=\"text-decoration: underline;\">virusuri Coxsackie A<\/span>, 23 serotipuri: 1-22 si 24;<\/p>\n<p style=\"padding-left: 30px;\">-<span style=\"text-decoration: underline;\">virusuri Coxsackie B<\/span>, 6 serotipuri: 1-6;<\/p>\n<p style=\"padding-left: 30px;\">-<span style=\"text-decoration: underline;\">Echovirusuri<\/span>, 29 serotipuri: 1-9,11-27, 29-31;<\/p>\n<p style=\"padding-left: 30px;\">-<span style=\"text-decoration: underline;\">Enterovirusuri \u201cnoi\u201d<\/span>: toate enterovirusurile descoperite din 1970 au fost incluse in genul enterovirus serotipurile 68-71 (virusul hepatitei A denumit initial enterovirus 72 a fost reclasificat ca hepadnavirus)<sup>1;3<\/sup>.<\/p>\n<p>Infectiile SNC induse de enterovirusuri includ:<\/p>\n<p style=\"padding-left: 30px;\">\u25cf <em><span style=\"text-decoration: underline;\">Meningita aseptica<\/span><\/em>: enterovirusurile constituie cea mai frecventa cauza de meningita aseptica (80-92%); serotipurile implicate sunt variabile iar manifestarile clinice depind de statusul imun al gazdei; tabloul clinic include invariabil cefalee si fotofobie; iritatia meningee dureaza &gt; 6 saptamani la 50% dintre pacienti dar anomaliile neurologice sunt rare si evolutia bolii este buna la pacientii imunocompetenti;<\/p>\n<p style=\"padding-left: 30px;\">\u25cf <em><span style=\"text-decoration: underline;\">Encefalita enterovirala<\/span><\/em>: este mai putin frecventa dar mai grava decat meningita aseptica; este caracterizata prin afectare focala similara encefalitei herpetice; adultii imunodeprimati si copiii cu agammaglobulinemie sunt susceptibili sa dezvolte meningita cronica sau meningoencefalita;<\/p>\n<p style=\"padding-left: 30px;\">\u25cf <em><span style=\"text-decoration: underline;\">Sindromul paralitic<\/span><\/em>: este asociat clasic cu virusurile polio; un sindrom similar poate fi indus de enterovirusurile 70\/71 si de virusul Coxsackie A7.<\/p>\n<p>Nou-nascutii infectati cu enterovirusuri prezinta o morbiditate si o mortalitate mare. In bolile febrile afectarea meningiana se produce in 70% din cazuri<sup>1<\/sup>.<\/p>\n<p>Diferentierea enterovirusurilor de alti agenti patogeni care determina infectii SNC este importanta pentru management-ul corect al pacientilor.<\/p>\n<p>Clasic, diagnosticul se stabileste prin izolarea virusului in culturi de celule, care dureaza in medie 6 zile. La ora actuala se considera ca detectarea ARN-ului viral reprezinta cea mai sensibila si rapida metoda de diagnostic a infectiilor SNC cauzate de enterovirusuri<sup>5<\/sup>.<\/p>\n<p>In scop epidemiologic ARN-ul viral mai poate fi depistat in probe provenite din tractul respirator superior precum si din materii fecale<sup>4<\/sup>.<\/p>\n<p><strong><em>Recomandari pentru determinarea Enterovirusuri \u2013 ARN <\/em><\/strong>\u2013 diagnosticul rapid al infectiilor SNC cauzate de enterovirusuri<sup>5<\/sup>.<\/p>\n<p><strong><em>Pregatire pacient<\/em><\/strong> \u2013 nu este necesara<sup>4<\/sup>.<\/p>\n<p><strong><em>Specimen recoltat<\/em><\/strong> \u2013 a) lichid cefalorahidian recoltat prin punctie lombara; b) exsudat faringian sau nazofaringian; c) materii fecale sau tampon rectal; d) sange EDTA<sup>4<\/sup>.<\/p>\n<p><strong><em>Recipient de recoltare<\/em><\/strong>\u00a0\u2013 a) recipient steril; b) tampon uscat; c) coprorecoltor fara mediu de transport sau tampon simplu; d) vacutainer ce contine EDTA ca anticoagulant<sup>4<\/sup>.<\/p>\n<p><strong><em>Cantitate recoltata <\/em><\/strong>\u2013 a) minimum 2 mL; c) 5 g; d) minimum 2 mL<sup>4<\/sup>.<\/p>\n<p><strong><em>Prelucrare necesara dupa recoltare <\/em><\/strong>\u2013 probele <strong>nu<\/strong> vor fi centrifugate<sup>4<\/sup>.<\/p>\n<p><strong><em>Stabilitate proba <\/em><\/strong>\u2013 probele sunt stabile <em>48 ore <\/em>la 2-4\u00b0C inainte de extractia acizilor nucleici<sup>4<\/sup>.<\/p>\n<p><strong><em>Metoda<\/em><\/strong> - <span style=\"text-decoration: underline;\">Real-time PCR Light-Cycler<\/span>: reactie de polimerizare in lant cu detectie in timp real a produsului PCR\u00a0 acumulat, prin masurarea fluorescentei emise (test calitativ); testul poate detecta toate tipurile de enterovirusuri<sup>4<\/sup>.<\/p>\n<p><strong><em>Valori de referinta <\/em><\/strong>\u2013 Enterovirusuri \u2013 ARN nedetectabil<sup>4<\/sup>.<\/p>\n<p><strong><em>Limita de detectie<\/em><\/strong> \u2013 10 copii\/proba<sup>4<\/sup>.<\/p>\n<p><strong><em>Interpretarea rezultatelor<\/em><\/strong><\/p>\n<p>Detectia Enterovirusuri-ARN in diverse produse patologice sustine diagnosticul clinic de infectie cauzata de un tip de enterovirusuri<sup>5<\/sup>.<\/p>\n<p><strong><em>Limite si interferente<\/em><\/strong><\/p>\n<p>Un rezultat negativ nu exclude posibilitatea unei infectii SNC cu enterovirusuri<sup>5<\/sup>.<\/p>\n<p><span style=\"font-size: small;\">\u00a0<\/span><\/p>\n<p><span style=\"font-size: small;\">\u0411\u0438\u0431\u043b\u0438\u043e\u0433\u0440\u0430\u0444\u0438\u044f<\/span><\/p>\n<p><span style=\"font-size: small;\">1. ARUP Laboratories. Test Directory: Coxsackie B Virus Antibodies; Echovirus Antibodies. <\/span><a href=\"http:\/\/www.aruplab.com\" rel=\"nofollow noopener\" target=\"_blank\"><span style=\"font-size: small;\">www.aruplab.com<\/span><\/a><span style=\"font-size: small;\"> 2015. Ref Type: Internet Communication.<\/span><\/p>\n<p><span style=\"font-size: small;\">2. Costin Cernescu. Picornaviridae. In Virusologie medicala, Editura medicala ,Bucuresti, 2003, 136.<\/span><\/p>\n<p><span style=\"font-size: small;\">3. John F. Modlin. Introduction to the Enteroviruses and Parechoviruses. In Mandelll, Douglas and Bennett\u2019s Principles and Practice of INFECTIOUS DISEASES, Seventh Edition, 2009, 2337-2342.<\/span><\/p>\n<p><span style=\"font-size: small;\">4. Laborator Synevo. Referintele specifice tehnologiei de lucru utilizate 2015. Ref Type: Catalog.<\/span><\/p>\n<p><span style=\"font-size: small;\">5. Mayo Clinic. Mayo Medical Laboratories. Test Catalog: Enterovirus, Molecular Detection, PCR, Spinal Fluid. www.mayomedicallaboratories.com. Ref Type: Internet Communication.<\/span><\/p>","protected":false},"excerpt":{"rendered":"<p><strong>\u041e\u0431\u0449\u0430\u044f \u0438\u043d\u0444\u043e\u0440\u043c\u0430\u0446\u0438\u044f<\/strong><\/p>\n<p>\u041e\u0431\u044b\u0447\u043d\u0430\u044f \u043a\u043b\u0430\u0441\u0441\u0438\u0444\u0438\u043a\u0430\u0446\u0438\u044f \u044d\u043d\u0442\u0435\u0440\u043e\u0432\u0438\u0440\u0443\u0441\u043e\u0432 \u0432\u043a\u043b\u044e\u0447\u0430\u0435\u0442 \u0432\u0438\u0440\u0443\u0441\u044b \u043f\u043e\u043b\u0438\u043e\u043c\u0438\u0435\u043b\u0438\u0442\u0430, \u041a\u043e\u043a\u0441\u0430\u043a\u0438 \u0438 \u042d\u0445\u043e (\u043a\u0438\u0448\u0435\u0447\u043d\u0430\u044f \u0446\u0438\u0442\u043e\u043f\u0430\u0442\u043e\u0433\u0435\u043d\u043d\u0430\u044f \u0447\u0435\u043b\u043e\u0432\u0435\u0447\u0435\u0441\u043a\u0430\u044f \u0441\u0438\u0440\u043e\u0442\u0430). \u041c\u0435\u0436\u0434\u0443 \u044d\u0442\u0438\u043c\u0438 \u0432\u0438\u0440\u0443\u0441\u0430\u043c\u0438 \u043d\u0435\u0442 \u0441\u0443\u0449\u0435\u0441\u0442\u0432\u0435\u043d\u043d\u044b\u0445 \u0440\u0430\u0437\u043b\u0438\u0447\u0438\u0439, \u0432\u0441\u0435 \u0438\u0437 \u043a\u043e\u0442\u043e\u0440\u044b\u0445 \u043e\u0431\u044b\u0447\u043d\u043e \u043e\u043f\u0440\u0435\u0434\u0435\u043b\u044f\u044e\u0442 \u0441\u0443\u0431\u043a\u043b\u0438\u043d\u0438\u0447\u0435\u0441\u043a\u0438\u0435 (\u0432\u043d\u0435\u0448\u043d\u0438\u0435) \u0438\u043d\u0444\u0435\u043a\u0446\u0438\u0438 \u043f\u0438\u0449\u0435\u0432\u0430\u0440\u0438\u0442\u0435\u043b\u044c\u043d\u043e\u0433\u043e \u0442\u0440\u0430\u043a\u0442\u0430, \u0430 \u0442\u0430\u043a\u0436\u0435 \u0448\u0438\u0440\u043e\u043a\u0438\u0439 \u0441\u043f\u0435\u043a\u0442\u0440 \u0434\u0440\u0443\u0433\u0438\u0445 \u0441\u0438\u043d\u0434\u0440\u043e\u043c\u043e\u0432. \u0412 \u0440\u0435\u0437\u0443\u043b\u044c\u0442\u0430\u0442\u0435 \u044d\u0444\u0444\u0435\u043a\u0442\u0438\u0432\u043d\u044b\u0445 \u0441\u0442\u0440\u0430\u0442\u0435\u0433\u0438\u0439 \u0432\u0430\u043a\u0446\u0438\u043d\u0430\u0446\u0438\u0438 \u0434\u0438\u043a\u0438\u0435 \u043f\u043e\u043b\u0438\u043e\u043c\u0438\u0435\u043b\u0438\u0442\u043d\u044b\u0435 \u0432\u0438\u0440\u0443\u0441\u044b 1-3 \u0446\u0438\u0440\u043a\u0443\u043b\u0438\u0440\u0443\u044e\u0442 \u0442\u043e\u043b\u044c\u043a\u043e \u0432 \u043e\u0433\u0440\u0430\u043d\u0438\u0447\u0435\u043d\u043d\u043e\u043c \u043a\u043e\u043b\u0438\u0447\u0435\u0441\u0442\u0432\u0435 \u0440\u0430\u0437\u0432\u0438\u0432\u0430\u044e\u0449\u0438\u0445\u0441\u044f \u0441\u0442\u0440\u0430\u043d.<\/p>\n<p>\u0412 \u0441\u0432\u043e\u044e \u043e\u0447\u0435\u0440\u0435\u0434\u044c, \u0432\u0438\u0440\u0443\u0441\u044b, \u043d\u0435 \u043e\u0442\u043d\u043e\u0441\u044f\u0449\u0438\u0435\u0441\u044f \u043a \u043f\u043e\u043b\u0438\u043e\u043c\u0438\u0435\u043b\u0438\u0442\u0443, \u0432\u043a\u043b\u044e\u0447\u0430\u044e\u0442:<\/p>\n<ul>\n<li>&#8211; \u0432\u0438\u0440\u0443\u0441\u044b \u041a\u043e\u043a\u0441\u0430\u043a\u0438 \u0410, 23 \u0441\u0435\u0440\u043e\u0442\u0438\u043f\u0430: 1-22 \u0438 24;<\/li>\n<li>\u0432\u0438\u0440\u0443\u0441\u044b \u041a\u043e\u043a\u0441\u0430\u043a\u0438 B, 6 \u0441\u0435\u0440\u043e\u0442\u0438\u043f\u043e\u0432: 1-6;<\/li>\n<li>\u042d\u0445\u043e\u0432\u0438\u0440\u0443\u0441\u044b, 29 \u0441\u0435\u0440\u043e\u0442\u0438\u043f\u043e\u0432: 1-9, 11-27, 29-31;<\/li>\n<li>\u201c\u041d\u043e\u0432\u044b\u0435 &#8221; \u044d\u043d\u0442\u0435\u0440\u043e\u0432\u0438\u0440\u0443\u0441\u044b: \u0432\u0441\u0435 \u044d\u043d\u0442\u0435\u0440\u043e\u0432\u0438\u0440\u0443\u0441\u044b, \u043e\u0431\u043d\u0430\u0440\u0443\u0436\u0435\u043d\u043d\u044b\u0435 \u0441 1970 \u0433\u043e\u0434\u0430, \u0431\u044b\u043b\u0438 \u0432\u043a\u043b\u044e\u0447\u0435\u043d\u044b \u0432 \u0440\u043e\u0434 \u044d\u043d\u0442\u0435\u0440\u043e\u0432\u0438\u0440\u0443\u0441\u043e\u0432 \u0441\u0435\u0440\u043e\u0442\u0438\u043f\u044b 68-71 (\u0432\u0438\u0440\u0443\u0441 \u0433\u0435\u043f\u0430\u0442\u0438\u0442\u0430 \u0410 \u043f\u0435\u0440\u0432\u043e\u043d\u0430\u0447\u0430\u043b\u044c\u043d\u043e \u043d\u0430\u0437\u044b\u0432\u0430\u043b\u0441\u044f \u044d\u043d\u0442\u0435\u0440\u043e\u0432\u0438\u0440\u0443\u0441 72 \u0431\u044b\u043b \u0440\u0435\u043a\u043b\u0430\u0441\u0441\u0438\u0444\u0438\u0446\u0438\u0440\u043e\u0432\u0430\u043d \u043a\u0430\u043a \u0433\u0435\u043f\u0430\u0434\u043d\u0430\u0432\u0438\u0440\u0443\u0441)<\/li>\n<\/ul>\n<p>\u0418\u043d\u0444\u0435\u043a\u0446\u0438\u0438 \u0426\u041d\u0421, \u0432\u044b\u0437\u0432\u0430\u043d\u043d\u044b\u0435 \u044d\u043d\u0442\u0435\u0440\u043e\u0432\u0438\u0440\u0443\u0441\u0430\u043c\u0438, \u0432\u043a\u043b\u044e\u0447\u0430\u044e\u0442:<\/p>\n<p>\u25cf \u0410\u0441\u0435\u043f\u0442\u0438\u0447\u0435\u0441\u043a\u0438\u0439 \u043c\u0435\u043d\u0438\u043d\u0433\u0438\u0442: \u044d\u043d\u0442\u0435\u0440\u043e\u0432\u0438\u0440\u0443\u0441\u044b \u044f\u0432\u043b\u044f\u044e\u0442\u0441\u044f \u043d\u0430\u0438\u0431\u043e\u043b\u0435\u0435 \u0447\u0430\u0441\u0442\u043e\u0439 \u043f\u0440\u0438\u0447\u0438\u043d\u043e\u0439 \u0430\u0441\u0435\u043f\u0442\u0438\u0447\u0435\u0441\u043a\u043e\u0433\u043e \u043c\u0435\u043d\u0438\u043d\u0433\u0438\u0442\u0430 (80-92%); \u0432\u043e\u0432\u043b\u0435\u0447\u0435\u043d\u043d\u044b\u0435 \u0441\u0435\u0440\u043e\u0442\u0438\u043f\u044b \u044f\u0432\u043b\u044f\u044e\u0442\u0441\u044f \u043f\u0435\u0440\u0435\u043c\u0435\u043d\u043d\u044b\u043c\u0438, \u0438 \u043a\u043b\u0438\u043d\u0438\u0447\u0435\u0441\u043a\u0438\u0435 \u043f\u0440\u043e\u044f\u0432\u043b\u0435\u043d\u0438\u044f \u0437\u0430\u0432\u0438\u0441\u044f\u0442 \u043e\u0442 \u0438\u043c\u043c\u0443\u043d\u043d\u043e\u0433\u043e \u0441\u0442\u0430\u0442\u0443\u0441\u0430 \u0445\u043e\u0437\u044f\u0438\u043d\u0430; \u043a\u043b\u0438\u043d\u0438\u0447\u0435\u0441\u043a\u0430\u044f \u043a\u0430\u0440\u0442\u0438\u043d\u0430 \u043d\u0435\u0438\u0437\u043c\u0435\u043d\u043d\u043e \u0432\u043a\u043b\u044e\u0447\u0430\u0435\u0442 \u0433\u043e\u043b\u043e\u0432\u043d\u0443\u044e \u0431\u043e\u043b\u044c \u0438 \u0441\u0432\u0435\u0442\u043e\u0431\u043e\u044f\u0437\u043d\u044c; \u043c\u0435\u043d\u0438\u043d\u0433\u0435\u0430\u043b\u044c\u043d\u043e\u0435 \u0440\u0430\u0437\u0434\u0440\u0430\u0436\u0435\u043d\u0438\u0435 \u0434\u043b\u0438\u0442\u0441\u044f &gt; 6 \u043d\u0435\u0434\u0435\u043b\u044c \u0443 50% \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u043e\u0432, \u043d\u043e \u043d\u0435\u0432\u0440\u043e\u043b\u043e\u0433\u0438\u0447\u0435\u0441\u043a\u0438\u0435 \u043d\u0430\u0440\u0443\u0448\u0435\u043d\u0438\u044f \u0440\u0435\u0434\u043a\u0438, \u0438 \u0440\u0430\u0437\u0432\u0438\u0442\u0438\u0435 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u044f \u0445\u043e\u0440\u043e\u0448\u0435\u0435 \u0443 \u0438\u043c\u043c\u0443\u043d\u043e\u043a\u043e\u043c\u043f\u0435\u0442\u0435\u043d\u0442\u043d\u044b\u0445 \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u043e\u0432.;<\/p>\n<p>\u25cf \u042d\u043d\u0442\u0435\u0440\u043e\u0432\u0438\u0440\u0443\u0441\u043d\u044b\u0439 \u044d\u043d\u0446\u0435\u0444\u0430\u043b\u0438\u0442 : \u043e\u043d \u043c\u0435\u043d\u0435\u0435 \u0440\u0430\u0441\u043f\u0440\u043e\u0441\u0442\u0440\u0430\u043d\u0435\u043d, \u043d\u043e \u0431\u043e\u043b\u0435\u0435 \u0441\u0435\u0440\u044c\u0435\u0437\u0435\u043d, \u0447\u0435\u043c \u0430\u0441\u0435\u043f\u0442\u0438\u0447\u0435\u0441\u043a\u0438\u0439 \u043c\u0435\u043d\u0438\u043d\u0433\u0438\u0442; \u043e\u043d \u0445\u0430\u0440\u0430\u043a\u0442\u0435\u0440\u0438\u0437\u0443\u0435\u0442\u0441\u044f \u043e\u0447\u0430\u0433\u043e\u0432\u044b\u043c \u043f\u043e\u0440\u0430\u0436\u0435\u043d\u0438\u0435\u043c, \u0430\u043d\u0430\u043b\u043e\u0433\u0438\u0447\u043d\u044b\u043c \u0433\u0435\u0440\u043f\u0435\u0442\u0438\u0447\u0435\u0441\u043a\u043e\u043c\u0443 \u044d\u043d\u0446\u0435\u0444\u0430\u043b\u0438\u0442\u0443; \u0443 \u0432\u0437\u0440\u043e\u0441\u043b\u044b\u0445 \u0441 \u043e\u0441\u043b\u0430\u0431\u043b\u0435\u043d\u043d\u044b\u043c \u0438\u043c\u043c\u0443\u043d\u0438\u0442\u0435\u0442\u043e\u043c \u0438 \u0434\u0435\u0442\u0435\u0439 \u0441 \u0430\u0433\u0430\u043c\u043c\u0430\u0433\u043b\u043e\u0431\u0443\u043b\u0438\u043d\u0435\u043c\u0438\u0435\u0439, \u0432\u0435\u0440\u043e\u044f\u0442\u043d\u043e, \u0440\u0430\u0437\u043e\u0432\u044c\u0435\u0442\u0441\u044f \u0445\u0440\u043e\u043d\u0438\u0447\u0435\u0441\u043a\u0438\u0439 \u043c\u0435\u043d\u0438\u043d\u0433\u0438\u0442 \u0438\u043b\u0438 \u043c\u0435\u043d\u0438\u043d\u0433\u043e\u044d\u043d\u0446\u0435\u0444\u0430\u043b\u0438\u0442;<\/p>\n<p>\u25cf \u041f\u0430\u0440\u0430\u043b\u0438\u0442\u0438\u0447\u0435\u0441\u043a\u0438\u0439 \u0441\u0438\u043d\u0434\u0440\u043e\u043c: \u043a\u043b\u0430\u0441\u0441\u0438\u0447\u0435\u0441\u043a\u0438 \u0441\u0432\u044f\u0437\u0430\u043d \u0441 \u0432\u0438\u0440\u0443\u0441\u0430\u043c\u0438 \u043f\u043e\u043b\u0438\u043e\u043c\u0438\u0435\u043b\u0438\u0442\u0430; \u043f\u043e\u0434\u043e\u0431\u043d\u044b\u0439 \u0441\u0438\u043d\u0434\u0440\u043e\u043c \u043c\u043e\u0436\u0435\u0442 \u0431\u044b\u0442\u044c \u0432\u044b\u0437\u0432\u0430\u043d \u044d\u043d\u0442\u0435\u0440\u043e\u0432\u0438\u0440\u0443\u0441\u0430\u043c\u0438 70\/71 \u0438 \u0432\u0438\u0440\u0443\u0441\u043e\u043c \u041a\u043e\u043a\u0441\u0430\u043a\u0438 A7.<\/p>\n<p>\u0423 \u043d\u043e\u0432\u043e\u0440\u043e\u0436\u0434\u0435\u043d\u043d\u044b\u0445, \u0438\u043d\u0444\u0438\u0446\u0438\u0440\u043e\u0432\u0430\u043d\u043d\u044b\u0445 \u044d\u043d\u0442\u0435\u0440\u043e\u0432\u0438\u0440\u0443\u0441\u0430\u043c\u0438, \u043d\u0430\u0431\u043b\u044e\u0434\u0430\u0435\u0442\u0441\u044f \u0432\u044b\u0441\u043e\u043a\u0430\u044f \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u0435\u043c\u043e\u0441\u0442\u044c \u0438 \u0441\u043c\u0435\u0440\u0442\u043d\u043e\u0441\u0442\u044c. \u041f\u0440\u0438 \u043b\u0438\u0445\u043e\u0440\u0430\u0434\u043e\u0447\u043d\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u044f\u0445 \u043c\u0435\u043d\u0438\u043d\u0433\u0438\u0430\u043b\u044c\u043d\u043e\u0435 \u043f\u043e\u0440\u0430\u0436\u0435\u043d\u0438\u0435 \u0432\u043e\u0437\u043d\u0438\u043a\u0430\u0435\u0442 \u0432 70% \u0441\u043b\u0443\u0447\u0430\u0435\u0432.<\/p>\n<p>\u0414\u0438\u0444\u0444\u0435\u0440\u0435\u043d\u0446\u0438\u0430\u0446\u0438\u044f \u044d\u043d\u0442\u0435\u0440\u043e\u0432\u0438\u0440\u0443\u0441\u043e\u0432 \u043e\u0442 \u0434\u0440\u0443\u0433\u0438\u0445 \u043f\u0430\u0442\u043e\u0433\u0435\u043d\u043e\u0432, \u0432\u044b\u0437\u044b\u0432\u0430\u044e\u0449\u0438\u0445 \u0438\u043d\u0444\u0435\u043a\u0446\u0438\u0438 \u0426\u041d\u0421, \u0432\u0430\u0436\u043d\u0430 \u0434\u043b\u044f \u043f\u0440\u0430\u0432\u0438\u043b\u044c\u043d\u043e\u0433\u043e \u0432\u0435\u0434\u0435\u043d\u0438\u044f \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u043e\u0432.<\/p>\n<p>\u041a\u043b\u0430\u0441\u0441\u0438\u0447\u0435\u0441\u043a\u0438 \u0434\u0438\u0430\u0433\u043d\u043e\u0437 \u0443\u0441\u0442\u0430\u043d\u0430\u0432\u043b\u0438\u0432\u0430\u0435\u0442\u0441\u044f \u043f\u0443\u0442\u0435\u043c \u0432\u044b\u0434\u0435\u043b\u0435\u043d\u0438\u044f \u0432\u0438\u0440\u0443\u0441\u0430 \u0432 \u043a\u043b\u0435\u0442\u043e\u0447\u043d\u044b\u0445 \u043a\u0443\u043b\u044c\u0442\u0443\u0440\u0430\u0445, \u0447\u0442\u043e \u0437\u0430\u043d\u0438\u043c\u0430\u0435\u0442 \u0432 \u0441\u0440\u0435\u0434\u043d\u0435\u043c 6 \u0434\u043d\u0435\u0439. \u0412 \u043d\u0430\u0441\u0442\u043e\u044f\u0449\u0435\u0435 \u0432\u0440\u0435\u043c\u044f \u0441\u0447\u0438\u0442\u0430\u0435\u0442\u0441\u044f, \u0447\u0442\u043e \u043e\u0431\u043d\u0430\u0440\u0443\u0436\u0435\u043d\u0438\u0435 \u0432\u0438\u0440\u0443\u0441\u043d\u043e\u0439 \u0420\u041d\u041a \u044f\u0432\u043b\u044f\u0435\u0442\u0441\u044f \u043d\u0430\u0438\u0431\u043e\u043b\u0435\u0435 \u0447\u0443\u0432\u0441\u0442\u0432\u0438\u0442\u0435\u043b\u044c\u043d\u044b\u043c \u0438 \u0431\u044b\u0441\u0442\u0440\u044b\u043c \u043c\u0435\u0442\u043e\u0434\u043e\u043c \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0438 \u0438\u043d\u0444\u0435\u043a\u0446\u0438\u0439 \u0426\u041d\u0421, \u0432\u044b\u0437\u0432\u0430\u043d\u043d\u044b\u0445 \u044d\u043d\u0442\u0435\u0440\u043e\u0432\u0438\u0440\u0443\u0441\u0430\u043c\u0438.<\/p>\n<p>\u0412 \u044d\u043f\u0438\u0434\u0435\u043c\u0438\u043e\u043b\u043e\u0433\u0438\u0447\u0435\u0441\u043a\u0438\u0445 \u0446\u0435\u043b\u044f\u0445 \u0432\u0438\u0440\u0443\u0441\u043d\u0430\u044f \u0420\u041d\u041a \u0432\u0441\u0435 \u0435\u0449\u0435 \u043c\u043e\u0436\u0435\u0442 \u0431\u044b\u0442\u044c \u043e\u0431\u043d\u0430\u0440\u0443\u0436\u0435\u043d\u0430 \u0432 \u043e\u0431\u0440\u0430\u0437\u0446\u0430\u0445 \u0438\u0437 \u0432\u0435\u0440\u0445\u043d\u0438\u0445 \u0434\u044b\u0445\u0430\u0442\u0435\u043b\u044c\u043d\u044b\u0445 \u043f\u0443\u0442\u0435\u0439, \u0430 \u0442\u0430\u043a\u0436\u0435 \u0438\u0437 \u0444\u0435\u043a\u0430\u043b\u0438\u0439.<\/p>\n<p>\u0420\u0435\u043a\u043e\u043c\u0435\u043d\u0434\u0430\u0446\u0438\u0438 \u043f\u043e \u043e\u043f\u0440\u0435\u0434\u0435\u043b\u0435\u043d\u0438\u044e \u044d\u043d\u0442\u0435\u0440\u043e\u0432\u0438\u0440\u0443\u0441\u043e\u0432-\u0420\u041d\u041a-\u0431\u044b\u0441\u0442\u0440\u0430\u044f \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0430 \u0438\u043d\u0444\u0435\u043a\u0446\u0438\u0439 \u0426\u041d\u0421, \u0432\u044b\u0437\u0432\u0430\u043d\u043d\u044b\u0445 \u044d\u043d\u0442\u0435\u0440\u043e\u0432\u0438\u0440\u0443\u0441\u0430\u043c\u0438.<\/p>\n<p><strong>\u041f\u043e\u0434\u0433\u043e\u0442\u043e\u0432\u043a\u0430 \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u0430<\/strong> &#8211; \u043d\u0435 \u0442\u0440\u0435\u0431\u0443\u0435\u0442\u0441\u044f.<\/p>\n<p><strong>\u0421\u043e\u0431\u0440\u0430\u043d\u043d\u044b\u0439 \u043e\u0431\u0440\u0430\u0437\u0435\u0446<\/strong> \u2013 \u0430) \u0441\u043f\u0438\u043d\u043d\u043e\u043c\u043e\u0437\u0433\u043e\u0432\u0430\u044f \u0436\u0438\u0434\u043a\u043e\u0441\u0442\u044c, \u0441\u043e\u0431\u0440\u0430\u043d\u043d\u0430\u044f \u043f\u0440\u0438 \u043b\u044e\u043c\u0431\u0430\u043b\u044c\u043d\u043e\u0439 \u043f\u0443\u043d\u043a\u0446\u0438\u0438; \u0431) \u044d\u043a\u0441\u0441\u0443\u0434\u0430\u0442 \u0433\u043b\u043e\u0442\u043a\u0438 \u0438\u043b\u0438 \u043d\u043e\u0441\u043e\u0433\u043b\u043e\u0442\u043a\u0438; \u0432) \u0444\u0435\u043a\u0430\u043b\u0438\u0438 \u0438\u043b\u0438 \u0440\u0435\u043a\u0442\u0430\u043b\u044c\u043d\u044b\u0439 \u0431\u0443\u0444\u0435\u0440; \u0433) \u043a\u0440\u043e\u0432\u044c EDTA.<\/p>\n<p><strong>\u041a\u043e\u043d\u0442\u0435\u0439\u043d\u0435\u0440 \u0434\u043b\u044f \u0441\u0431\u043e\u0440\u0430<\/strong>-\u0430) \u0441\u0442\u0435\u0440\u0438\u043b\u044c\u043d\u044b\u0439 \u043a\u043e\u043d\u0442\u0435\u0439\u043d\u0435\u0440; 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\u0442\u0435\u0441\u0442 \u043c\u043e\u0436\u0435\u0442 \u043e\u0431\u043d\u0430\u0440\u0443\u0436\u0438\u0442\u044c \u0432\u0441\u0435 \u0442\u0438\u043f\u044b \u044d\u043d\u0442\u0435\u0440\u043e\u0432\u0438\u0440\u0443\u0441\u043e\u0432.<\/p>\n<p><strong>\u0420\u0435\u0444\u0435\u0440\u0435\u043d\u0442\u043d\u044b\u0435 \u0437\u043d\u0430\u0447\u0435\u043d\u0438\u044f<\/strong>-\u044d\u043d\u0442\u0435\u0440\u043e\u0432\u0438\u0440\u0443\u0441\u044b-\u043d\u0435\u043e\u0431\u043d\u0430\u0440\u0443\u0436\u0438\u043c\u0430\u044f \u0420\u041d\u041a.<\/p>\n<p><strong>\u041f\u0440\u0435\u0434\u0435\u043b \u043e\u0431\u043d\u0430\u0440\u0443\u0436\u0435\u043d\u0438\u044f<\/strong> &#8211; 10 \u0434\u0435\u0442\u0435\u0439 \/ \u043f\u0440\u043e\u0431\u0430.<\/p>\n<p><strong>\u0418\u043d\u0442\u0435\u0440\u043f\u0440\u0435\u0442\u0430\u0446\u0438\u044f \u0440\u0435\u0437\u0443\u043b\u044c\u0442\u0430\u0442\u043e\u0432<\/strong><\/p>\n<p>\u041e\u0431\u043d\u0430\u0440\u0443\u0436\u0435\u043d\u0438\u0435 \u044d\u043d\u0442\u0435\u0440\u043e\u0432\u0438\u0440\u0443\u0441\u043e\u0432-\u0420\u041d\u041a \u0432 \u0440\u0430\u0437\u043b\u0438\u0447\u043d\u044b\u0445 \u043f\u0430\u0442\u043e\u043b\u043e\u0433\u0438\u0447\u0435\u0441\u043a\u0438\u0445 \u043f\u0440\u043e\u0434\u0443\u043a\u0442\u0430\u0445 \u043f\u043e\u0434\u0434\u0435\u0440\u0436\u0438\u0432\u0430\u0435\u0442 \u043a\u043b\u0438\u043d\u0438\u0447\u0435\u0441\u043a\u0438\u0439 \u0434\u0438\u0430\u0433\u043d\u043e\u0437 \u0438\u043d\u0444\u0435\u043a\u0446\u0438\u0438, \u0432\u044b\u0437\u0432\u0430\u043d\u043d\u043e\u0439 \u0442\u0438\u043f\u043e\u043c \u044d\u043d\u0442\u0435\u0440\u043e\u0432\u0438\u0440\u0443\u0441\u043e\u0432.<\/p>\n<p>\u041e\u0442\u0440\u0438\u0446\u0430\u0442\u0435\u043b\u044c\u043d\u044b\u0439 \u0440\u0435\u0437\u0443\u043b\u044c\u0442\u0430\u0442 \u043d\u0435 \u0438\u0441\u043a\u043b\u044e\u0447\u0430\u0435\u0442 \u0432\u043e\u0437\u043c\u043e\u0436\u043d\u043e\u0441\u0442\u0438 \u0437\u0430\u0440\u0430\u0436\u0435\u043d\u0438\u044f \u0426\u041d\u0421 \u044d\u043d\u0442\u0435\u0440\u043e\u0432\u0438\u0440\u0443\u0441\u0430\u043c\u0438.<\/p>","protected":false},"featured_media":0,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[971],"product_tag":[],"class_list":{"0":"post-10200","1":"product","2":"type-product","3":"status-publish","5":"product_cat-teste-moleculare-pentru-diagnosticul-infectiilor","7":"first","8":"instock","9":"sold-individually","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/product\/10200","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/comments?post=10200"}],"wp:attachment":[{"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/media?parent=10200"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/product_brand?post=10200"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/product_cat?post=10200"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/product_tag?post=10200"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}