{"id":10141,"date":"2020-04-23T03:57:47","date_gmt":"2020-04-23T00:57:47","guid":{"rendered":"https:\/\/www.synevo.ro\/product\/anticorpi-anti-miocard\/"},"modified":"2024-11-27T16:49:12","modified_gmt":"2024-11-27T14:49:12","slug":"anticorpi-anti-miocard","status":"publish","type":"product","link":"https:\/\/old.synevo.md\/ru\/shop\/anticorpi-anti-miocard\/","title":{"rendered":"\u0410\u043d\u0442\u0438\u043c\u0438\u043e\u043a\u0430\u0440\u0434\u0438\u0430\u043b\u044c\u043d\u044b\u0435 \u0430\u043d\u0442\u0438\u0442\u0435\u043b\u0430"},"content":{"rendered":"

\u041e\u0431\u0449\u0430\u044f \u0438\u043d\u0444\u043e\u0440\u043c\u0430\u0446\u0438\u044f<\/em><\/strong><\/p>\n

Anticorpii anti-miocard sunt autoanticorpi \u00eendrepta\u0163i \u00eempotriva fibrelor musculare cardiace. De\u015fi ace\u015ftia pot fi utiliza\u0163i pentru diferen\u0163ierea cardiomiopatiilor mediate imun de alte cauze de miocardit\u0103, prezen\u0163a lor poate fi eviden\u0163iat\u0103 la majoritatea pacien\u0163ilor care au suferit chirurgie cardiac\u0103 (by-pass al arterelor coronare) sau infarct miocardic.<\/p>\n

\u00cen numeroase afec\u0163iuni reumatismale s-au constatat depozite de imunoglobuline \u00een mu\u015fchiul cardiac suger\u00e2nd implicarea mecanismului autoimun. Pot fi afectate membrana bazal\u0103 sarcolemal\u0103, fibrele \u015fi vasele, individual sau \u00eempreun\u0103.<\/p>\n

Autoanticorpii apar, de obicei, dup\u0103 o interven\u0163ie chirurgical\u0103 cardiac\u0103, dar pot fi prezen\u0163i \u015fi \u00eenainte de aceasta. La 30% dintre persoanele cu infarct miocardic \u015fi 70% dintre cei care au fost supu\u015fi unei interven\u0163ii chirurgicale anticorpii antimiocard vor ap\u0103rea \u00een termen de 2-3 s\u0103pt\u0103m\u00e2ni \u015fi r\u0103m\u00e2n persisten\u0163i \u00een ser p\u00e2n\u0103 la 3-8 s\u0103pt\u0103m\u00e2ni. Semnifica\u0163ia clinic\u0103 a acestei constat\u0103ri nu este cert\u0103, autoanticorpii put\u00e2nd fi g\u0103si\u0163i, de asemenea, la pacien\u0163ii care sufer\u0103 de diverse afec\u0163iuni reumatice, cum ar fi reumatismul articular acut. De\u015fi prezen\u0163a anticorpilor nu poate diagnostica afec\u0163iunile cardiace, exist\u0103 o leg\u0103tur\u0103 \u00eentre prezen\u0163a acestor anticorpi \u015fi deteriorarea mu\u015fchiului cardiac, dar cantitatea de anticorpi prezen\u0163i \u00een ser nu este direct propor\u0163ional\u0103 cu leziunile existente1;3;4<\/sup>. \u00a0<\/em><\/strong><\/p>\n

Recomand\u0103ri pentru determinarea anticorpilor anti-miocard <\/em><\/strong>\u2013 utilitate \u00een diagnosticul cardiomiopatiilor2<\/sup>.<\/p>\n

Preg\u0103tire pacient<\/em><\/strong> \u2013 \u00e0 jeun (pe nem\u00e2ncate)1<\/sup>.<\/p>\n

Specimen recoltat<\/em><\/strong> \u2013 s\u00e2nge venos3<\/sup>.<\/p>\n

Recipient de recoltare <\/em><\/strong>-<\/em> vacutainer f\u0103r\u0103 anticoagulant cu\/f\u0103r\u0103 gel separator1<\/sup>.<\/p>\n

Prelucrare necesar\u0103 dup\u0103 recoltare<\/em><\/strong> - <\/em>se separ\u0103 serul prin centrifugare1<\/sup>.<\/p>\n

Cantitate recoltat\u0103 <\/em><\/strong>\u2013 1 mL1<\/sup>.<\/p>\n

Cauze\u00a0 de respingere a probei<\/em><\/strong> - <\/em>specimen intens hemolizat\/lipemic\/contaminat bacterian1<\/sup>.<\/p>\n

Stabilitate prob\u0103 <\/em><\/strong>\u2013 serul separat este stabil 7 zile<\/em> la 2-4\u00b0C \u015fi 1 lun\u0103 <\/em>la -20\u00b0C1<\/sup>.<\/p>\n

Metod\u0103<\/em><\/strong> \u2013 imunofluorescen\u0163a indirect\u01031<\/sup>.<\/p>\n

Valori de referin\u0163\u0103 <\/em><\/strong>\u2013 <1\/10. Rezultatele sunt comunicate sub form\u0103 de titru1<\/sup>. \u00a0<\/em><\/strong><\/p>\n

\u00a0<\/em><\/strong><\/p>\n

\u0411\u0438\u0431\u043b\u0438\u043e\u0433\u0440\u0430\u0444\u0438\u044f<\/span><\/strong><\/p>\n

1. David J. Bylund, Robert M. Nakamura. Organ-Specific Autoimmune Diseases. In Henry\u2019s Clinical Diagnosis and Management by Laboratory Methods, Saunders-Elsevier, 21st Edition, 958.<\/span><\/span><\/div>\n
2. Laborator Synevo. Referin\u0163e specifice tehnologiei de lucru utilizate 2010. Ref Type: Catalog.<\/span><\/div>\n
3. Laboratory Corporation of America. Directory of Services and Interpretive Guide. Antimyocardial Antibodies, Quantitative. www.labcorp.com 2010. Ref Type: Internet Communication.<\/span><\/div>\n
4. www.healthline.com\/galecontent\/antimyocardial-antibody-test.<\/span><\/div>","protected":false},"excerpt":{"rendered":"

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\u0418\u043d\u0442\u0435\u0440\u043f\u0440\u0435\u0442\u0430\u0446\u0438\u044f\u00a0\u0440\u0435\u0437\u0443\u043b\u044c\u0442\u0430\u0442\u043e\u0432<\/b><\/td>\n<\/tr>\n
\u041f\u043e\u0432\u044b\u0448\u0435\u043d\u0438\u0435\u00a0\u0443\u0440\u043e\u0432\u043d\u044f<\/b><\/td>\n<\/tr>\n
\u00b7\u00a0\u041c\u0438\u043e\u043a\u0430\u0440\u0434\u0438\u0442;<\/p>\n

\u00b7\u00a0\u0434\u0438\u043b\u0430\u0442\u0430\u0446\u0438\u043e\u043d\u043d\u0430\u044f\u00a0\u043a\u0430\u0440\u0434\u0438\u043e\u043c\u0438\u043e\u043f\u0430\u0442\u0438\u044f\u00a0(\u043f\u0440\u0438\u00a0\u043f\u0440\u043e\u0433\u0440\u0435\u0441\u0441\u0438\u0440\u043e\u0432\u0430\u043d\u0438\u0438\u00a0\u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u044f\u00a0\u0443\u0440\u043e\u0432\u0435\u043d\u044c\u00a0\u0430\u043d\u0442\u0438\u0442\u0435\u043b\u00a0\u043c\u043e\u0436\u0435\u0442\u00a0\u0441\u043d\u0438\u0436\u0430\u0442\u044c\u0441\u044f);<\/p>\n

\u00b7\u00a0\u0441\u043e\u0441\u0442\u043e\u044f\u043d\u0438\u0435\u00a0\u043f\u043e\u0441\u043b\u0435\u00a0\u043e\u043f\u0435\u0440\u0430\u0446\u0438\u0439\u00a0\u043d\u0430\u00a0\u0441\u0435\u0440\u0434\u0446\u0435;<\/p>\n

\u00b7\u00a0\u043b\u0451\u0433\u043e\u0447\u043d\u043e\u0435\u00a0\u0441\u0435\u0440\u0434\u0446\u0435;<\/p>\n

\u00b7\u00a0\u0438\u0448\u0435\u043c\u0438\u0447\u0435\u0441\u043a\u0430\u044f\u00a0\u0431\u043e\u043b\u0435\u0437\u043d\u044c\u00a0\u0441\u0435\u0440\u0434\u0446\u0430\u00a0(\u0440\u0435\u0434\u043a\u043e);<\/p>\n

\u00b7\u00a0\u0434\u0440\u0443\u0433\u0438\u0435\u00a0\u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u044f\u00a0\u0441\u0435\u0440\u0434\u0446\u0430\u00a0(\u0440\u0435\u0434\u043a\u043e);<\/p>\n

\u00b7\u00a0\u0437\u0434\u043e\u0440\u043e\u0432\u044b\u0435\u00a0\u043b\u044e\u0434\u0438\u00a0(\u0440\u0435\u0434\u043a\u043e)<\/td>\n<\/tr>\n<\/tbody>\n<\/table>","protected":false},"featured_media":0,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[933,928],"product_tag":[],"class_list":{"0":"post-10141","1":"product","2":"type-product","3":"status-publish","5":"product_cat-autoanticorpi-in-afectiuni-endocrine-cardiace-renale","6":"product_cat-markeri-boli-autoimune","8":"first","9":"instock","10":"sold-individually","11":"shipping-taxable","12":"purchasable","13":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/product\/10141","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/comments?post=10141"}],"wp:attachment":[{"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/media?parent=10141"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/product_brand?post=10141"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/product_cat?post=10141"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/old.synevo.md\/ru\/wp-json\/wp\/v2\/product_tag?post=10141"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}